3D printed nitric oxide-releasing poly(acrylic acid)/F127/cellulose nanocrystal hydrogels

Abstract

Hydrogels have been used as matrices for the topical delivery of nitric oxide (NO) for obtaining vasodilation, wound healing and analgesic actions. More recently, supramolecular hydrogels comprised of poly(acrylic acid)...

Nanocellulose-based hydrogels for drug delivery

“…The pore structure, arrangement and hardness of the hydrogel were improved, leading to significant rigidity, swelling and well-performed drug loading/release behavior. Recently, Santos et al 83 used CNCs, PAA and Pluronic F-127 as raw materials to prepare 3D printable semi-interpenetrating hydrogels with high fidelity through PAA photopolymerization (Fig. 6b).…”

The Next Frontier of 3D Bioprinting: Bioactive Materials Functionalized by Bacteria

“…The source can be divided into two types of network precursors: synthetic polymers and natural biological macromolecules. [ 25 ] The former mainly originates from the chemical industry, such as Pluronic, [ 28 ] polyethylene glycol, [ 29 ] and polyvinyl alcohol, [ 30 ] and its physical properties are easy to adjust, but its biocompatibility is poor.…”

Electrochemical generation of nitric oxide for medical applications

“…nanoparticles and hydrogels can be quite useful in woundhealing applications. [72][73][74][75] We have reported the adaptation of our E-NOgen technology within silicone-rubber patches that can controllably release NO directionally from one surface of the patch (Figure 2c). 76 The device consists of a 10-40 × 10-40 × 5-10 mm patch (several dimensions were fabricated/tested) made from polydimethylsiloxane (PDMS) housing, a cheap and flexible material.…”