3D printed deformable sensors

Zhu, Zhijie; Park, Hyun Soo; McAlpine, Michael C.

doi:10.1126/sciadv.aba5575

Cited by 139 publications

(102 citation statements)

References 45 publications

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“…To deal with those issues, a latest research proposed a novel printing procedure to fabricate an electrical-impedance-tomography strain sensor on an ex-vivo breathing lung. The authors integrate a visual sensing system with a 3D printer to track the time-varying 3D geometry of the lung (Zhu et al, 2020 ). The method presented in the abovementioned research could aid modern medical treatments in myriad ways, such as printing electrode arrays for neural interfaces and printing bioscaffolds with engineered cells for tissue regeneration.…”

Section: Discussion and Future Directionsmentioning

confidence: 99%

COVID-19 Pandemic Spurs Medical Telerobotic Systems: A Survey of Applications Requiring Physiological Organ Motion Compensation

Cheng

Tavakoli

2020

Front. Robot. AI

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The coronavirus disease 2019 (COVID-19) pandemic has resulted in public health interventions such as physical distancing restrictions to limit the spread and transmission of the novel coronavirus, causing significant effects on the delivery of physical healthcare procedures worldwide. The unprecedented pandemic spurs strong demand for intelligent robotic systems in healthcare. In particular, medical telerobotic systems can play a positive role in the provision of telemedicine to both COVID-19 and non-COVID-19 patients. Different from typical studies on medical teleoperation that consider problems such as time delay and information loss in long-distance communication, this survey addresses the consequences of physiological organ motion when using teleoperation systems to create physical distancing between clinicians and patients in the COVID-19 era. We focus on the control-theoretic approaches that have been developed to address inherent robot control issues associated with organ motion. The state-of-the-art telerobotic systems and their applications in COVID-19 healthcare delivery are reviewed, and possible future directions are outlined.

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Section: Discussion and Future Directionsmentioning

confidence: 99%

COVID-19 Pandemic Spurs Medical Telerobotic Systems: A Survey of Applications Requiring Physiological Organ Motion Compensation

Cheng

Tavakoli

2020

Front. Robot. AI

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“…Although the reported sensor fabrication was not a bioprinting process, this approach has great potential to be adapted for in situ bioprinting. 187 Moreover, near-infrared light has been used for in situ bioprinting due to its enhanced penetration depth into skin. 189,190 Chen et al formulated GelMA-based bioinks supplemented with a nanoinitiator to cross-linking the GelMA under 980 nm near-infrared light.…”

Section: Emerging Approachesmentioning

confidence: 99%

Complex 3D bioprinting methods

Guvendiren

2021

APL Bioengineering

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3D bioprinting technology is evolving in complexity to enable human-scale, high-resolution, and multi-cellular constructs to better mimic the native tissue microenvironment. The ultimate goal is to achieve necessary complexity in the bioprinting process to biomanufacture fully-functional tissues and organs to address organ shortage and lack of patient-specific disease models. In this Review, we presented an in-depth overview of complex 3D bioprinting approaches including evolution of complex bioprinting, from simple gel-casting approach to multi-material bioprinting to omnidirectional bioprinting approaches, and emerging bioprinting approaches, including 4D bioprinting and in situ bioprinting technologies.

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“…These drawbacks are driving research boundaries of 3D printing to address new challenges and prior limitations. Recently, 3D printing has been utilized for in situ printing of deformable sensors right onto soft tissues and organs to accommodate its movement and expansions [115]. This flexibility in the applications of 3D printing materials with different characteristics expose the power of this technique in exploring what has been previously limited to sophisticated equipment and complex fabrication facilities.…”

Section: Challenges and Future Perspectivesmentioning

confidence: 99%

3D-Printed Immunosensor Arrays for Cancer Diagnostics

Sharafeldin

Kadimisetty

Bhalerao

et al. 2020

Sensors

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Detecting cancer at an early stage of disease progression promises better treatment outcomes and longer lifespans for cancer survivors. Research has been directed towards the development of accessible and highly sensitive cancer diagnostic tools, many of which rely on protein biomarkers and biomarker panels which are overexpressed in body fluids and associated with different types of cancer. Protein biomarker detection for point-of-care (POC) use requires the development of sensitive, noninvasive liquid biopsy cancer diagnostics that overcome the limitations and low sensitivities associated with current dependence upon imaging and invasive biopsies. Among many endeavors to produce user-friendly, semi-automated, and sensitive protein biomarker sensors, 3D printing is rapidly becoming an important contemporary tool for achieving these goals. Supported by the widely available selection of affordable desktop 3D printers and diverse printing options, 3D printing is becoming a standard tool for developing low-cost immunosensors that can also be used to make final commercial products. In the last few years, 3D printing platforms have been used to produce complex sensor devices with high resolution, tailored towards researchers’ and clinicians’ needs and limited only by their imagination. Unlike traditional subtractive manufacturing, 3D printing, also known as additive manufacturing, has drastically reduced the time of sensor and sensor array development while offering excellent sensitivity at a fraction of the cost of conventional technologies such as photolithography. In this review, we offer a comprehensive description of 3D printing techniques commonly used to develop immunosensors, arrays, and microfluidic arrays. In addition, recent applications utilizing 3D printing in immunosensors integrated with different signal transduction strategies are described. These applications include electrochemical, chemiluminescent (CL), and electrochemiluminescent (ECL) 3D-printed immunosensors. Finally, we discuss current challenges and limitations associated with available 3D printing technology and future directions of this field.

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3D printed deformable sensors

Cited by 139 publications

References 45 publications

COVID-19 Pandemic Spurs Medical Telerobotic Systems: A Survey of Applications Requiring Physiological Organ Motion Compensation

COVID-19 Pandemic Spurs Medical Telerobotic Systems: A Survey of Applications Requiring Physiological Organ Motion Compensation

Complex 3D bioprinting methods

3D-Printed Immunosensor Arrays for Cancer Diagnostics

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