3D powder printed calcium phosphate implants for reconstruction of cranial and maxillofacial defects

Klammert, Uwe; Gbureck, Uwe; Vorndran, Elke; Rödiger, Jan; Meyer-Marcotty, Philipp; Kübler, Alexander C.

doi:10.1016/j.jcms.2010.01.009

Cited by 194 publications

(133 citation statements)

References 22 publications

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“…Calcium phosphate bind to living bone, giving these materials advantages as bone scaffold material. Klammert et al 35 fabricated brushite (di CaP dihydrate) and monetite (di CaP anhydrous) 3D scaffolds to demonstrate the capability of 3DP for reconstruction of cranial defects and concluded that 3DP implants complied with the geometric requirements and provided an adequate fit. These investigators fabricated anatomically shaped scaffolds using CAD files generated by scanning a human cadaver skull having specific cranial defects.…”

Section: In Vitro and In Vivo Testing Of 3dp Bone Scaffoldsmentioning

confidence: 99%

3D Printing of Personalized Artificial Bone Scaffolds

Jariwala

Lewis

Bushman

et al. 2015

3D Printing and Additive Manufacturing

131

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Section: In Vitro and In Vivo Testing Of 3dp Bone Scaffoldsmentioning

confidence: 99%

3D Printing of Personalized Artificial Bone Scaffolds

Jariwala

Lewis

Bushman

et al. 2015

3D Printing and Additive Manufacturing

131

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“…Additionally, additive manufacturing enables the incorporation of drugs/proteins as well as cells during scaffold [32] manufacturing to produce very complex architecture similar to bone [37][38][39]. Therefore, additive manufacturing methodology is widely used for the formation of biological bone scaffolds.…”

Section: Formation Methods Of Bone Scaffoldsmentioning

confidence: 99%

Application of 3D printing technology in bone tissue engineering

Wang

Wei

et al. 2018

Bio-des. Manuf.

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“…For ARCAM A1 the resolution is ±0.4 mm based on the information in the user's manual. Irrespective of the above, compressive strength, endurance and elastic modulus can be optimized to ensure the long term success of the implant [1,[29][30][31][32]. Vascularization is another aspect that merits consideration during design, because vascularization promotes diffusion of nutrients that is necessary for cell proliferation and differentiation.…”

Section: Design Considerationsmentioning

confidence: 99%

Advancements in three-dimensional titanium alloy mesh scaffolds fabricated by electron beam melting for biomedical devices: mechanical and biological aspects

Nune

Misra

2017

Sci. China Mater.

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We elucidate here the process-structure-property relationships in three-dimensional (3D) implantable titanium alloy biomaterials processed by electron beam melting (EBM) that is based on the principle of additive manufacturing. The conventional methods for processing of biomedical devices including freeze casting and sintering are limited because of the difficulties in adaptation at the host site and difference in the micro/macrostructure, mechanical, and physical properties with the host tissue. In this regard, EBM has a unique advantage of processing patient-specific complex designs, which can be either obtained from the computed tomography (CT) scan of the defect site or through a computeraided design (CAD) program. This review introduces and summarizes the evolution and underlying reasons that have motivated 3D printing of scaffolds for tissue regeneration. The overview comprises of two parts for obtaining ultimate functionalities. The first part focuses on obtaining the ultimate functionalities in terms of mechanical properties of 3D titanium alloy scaffolds fabricated by EBM with different characteristics based on design, unit cell, processing parameters, scan speed, porosity, and heat treatment. The second part focuses on the advancement of enhancing biological responses of these 3D scaffolds and the influence of surface modification on cell-material interactions. The overview concludes with a discussion on the clinical trials of these 3D porous scaffolds illustrating their potential in meeting the current needs of the biomedical industry.

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3D powder printed calcium phosphate implants for reconstruction of cranial and maxillofacial defects

Cited by 194 publications

References 22 publications

3D Printing of Personalized Artificial Bone Scaffolds

3D Printing of Personalized Artificial Bone Scaffolds

Application of 3D printing technology in bone tissue engineering

Advancements in three-dimensional titanium alloy mesh scaffolds fabricated by electron beam melting for biomedical devices: mechanical and biological aspects

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