3D Bio-Cad modeling of human mandible and fabrication by rapid-prototyping technology

Abstract

The purpose of this study is to prepare a model of the human mandible in accordance with anatomical structure and fabricated by rapid-prototyping (RP) technology. In this study, a computed tomographic (CT) scan of a dentate mandible was obtained with a 0.3 mm voxel resolution with capability to export to DICOM format. The data were cleaned; edited and separated 'mask' generated for cortical bone, cancellous bone, and teeth using Mimics 10.01 and Geomagic 11.0 software. The data were imported to Solidworks from Geomagic and converted to the solid model and fabricated by 3D rapid-prototyping technique. The mandible structure was divided into layers and then an average Young's modulus value was calculated for each layer of cortical bone and cancellous bone using the basis of CT density as in previously published protocols. In this study, the procedure of obtaining bio-CAD model of mandible methodology has nine phases: computed tomography (CT), 2D segmentation, calculating 3D object from scanned data, reverse engineering interface, point cloud data processing, surface reconstruction, solid model reconstruction, obtaining bio-CAD model, and fabricating the model using RP technology. The average Young's Modulus value of cortical bone and cancellous bone was calculated 30100.88 MPa, and 685.42 MPa, respectively. As a result, according to expert review, examination of the anatomical structure, and literature survey, we concluded that the development of 3D human mandible model can be used to conduct research on human mandible.

Sex and age biological variation of the mandible in a Portuguese population- a forensic and medico-legal approaches with three-dimensional analysis

“…We can consider as limitations of the study the existence of different methods to evaluate the structural mandibular bone, without a standardization of landmarks [40]. The study material (CBCT), carried out in the living, with standardized parameterization in its acquisition (exposure times and values) made the construction of a 3D anatomical and geometric model of a human mandible a complex procedure [28,48]. In addition, regarding the literature cited, the characterization of the age range is older than our sample.…”

Evaluation of Biodegradable Fixation System for Mandibular Angulus Fracture by Using Finite Element Method

“…Bio-CAD modeling In this study, according to the procedure previously reported by Sun et al, an image based bio-CAD modeling process was utilized [6], which involves following three major steps: (1) noninvasive image acquisition, (2) imaging process and three dimensional reconstructions (3DR) to form voxel-based volumetric image representation, and (3) construction of CAD-based model. * corresponding author; e-mail: selimh@marmara.edu.tr Furthermore, the obtained bio-CAD model was fabricated using rapid prototyping technology.…”

Computational Simulation as an Innovative Approach in Personalized Medicine

“…The existing process chain without considering the biomechanical simulation includes the image acquisition, the image post-processing and the rapid prototyping [4,5]. The image raw data acquired using CT or MRI are segmented, visualized and transferred in a suitable data format by image post-processing.…”

“…According to Sun et al [8], the CT number can be correlated to the density, for example, of the bone by a linear interpolation using relations available in published literature. The determined density can then be related to the so-called Young's modulus E. The heterogeneous elasticity, for example, of the cancellous and cortical bone, can in turn be defined by the following relationships [5]:…”