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Anacona, J.R.; Azocar, Mary; Nusetti, Osmar; Rodríguez-Barbarín, Cecilia

doi:10.1023/a:1022557523959

Cited by 24 publications

(15 citation statements)

References 22 publications

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“…Although it is quite difficult to comment on the molecular structure of these compounds without X-ray crystal structure analysis, a number of cobalt(II) structures have been described as tetrahedral [40][41][42][43][44]. The two pyrazoline ligands are bidentate in complexes of the type (C 15 H 12 N 2 OX) 2 Co and monodentate in the addition complexes, and tetrahedral geometry around cobalt(II) is proposed.…”

Section: Resultsmentioning

confidence: 99%

Synthesis, spectral and biological investigations of 5(2′-hydroxyphenyl)-3-(4-substituted-phenyl) pyrazolinates of cobalt(II) and their addition complexes with N, P donor ligands

Sharma¹,

Sharma²,

Tripathi

2009

Journal of Coordination Chemistry

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5(2 0 -Hydroxyphenyl)-3-(4-substituted-phenyl)pyrazolinates of cobalt(II) of the type (C 15 H 12 N 2 OX) 2 Co [here substituted group X is -H, -Cl, -CH 3 or -OCH 3 ] have been synthesized by reaction of anhydrous cobalt(II)chloride with the sodium salt of the pyrazolines in 1 : 2 molar ratio. Their addition complexes with N and P donor ligands [2, 2 0 -bipyridine, 1, 10-phenanthroline and triphenylphosphine] were prepared in 1 : 1 molar ratio. The newly synthesized complexes were characterized by elemental analyses, molecular weight measurement, magnetic susceptibility, IR, electronic, 31 P NMR and FAB mass spectra. All complexes are amorphous as determined by XRD. Tetrahedral geometry around cobalt(II) has been suggested, confirming the presence of two pyrazoline bidentate ligands, cobalt(II)5-(2 0 -hydroxyphenyl)-3-(4-substituted-phenyl)pyrazolinates. Upon ligand addition, pyrazoline changes to monodentate. The bidentate and monodentate behavior of pyrazoline ligands was confirmed by IR spectral data. The metal complexes and their adducts exhibit good antibacterial and antifungal activity, better than the pyrazolines.

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Section: Resultsmentioning

confidence: 99%

Synthesis, spectral and biological investigations of 5(2′-hydroxyphenyl)-3-(4-substituted-phenyl) pyrazolinates of cobalt(II) and their addition complexes with N, P donor ligands

Sharma¹,

Sharma²,

Tripathi

2009

Journal of Coordination Chemistry

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“…Although the SOD activity is not higher than some already reported, it presents higher percentages of SOD activity than the [Co(quinoline) 2 (SH) 2 ] complex [22] and appears to be a promising SOD mimic. …”

Section: Resultsmentioning

confidence: 50%

“…The other two classes of SODs that contain iron or manganese have received less attention and their structures have only been recently described [14][15][16]. However, some iron [4,17,18], manganese [4,17,19], ruthenium [20] and cobalt [21] SOD mimics have been reported and some show marked SOD activity and seem to retain it in living cells [22,23].…”

Section: Introductionmentioning

confidence: 99%

Synthesis, crystal structure and superoxide dismutase activity of [pyrrolidinium][Co(sulfathiazole)₃(pyrrolidine)]

Anacona

Loroño

Azocar

et al. 2009

Journal of Coordination Chemistry

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Synthesis, crystal structure and superoxide dismutase activity of [pyrrolidinium] [Co(sulfathiazole) 3 (pyrrolidine)], Journal of Coordination Chemistry, 62:6, 951-957,The preparation, spectroscopic properties and crystal structure of [pyrrolidinium] [Co(sulfathiazole) 3 (pyrrolidine)] are reported. The X-ray structure reveals tetrahedral geometry around cobalt. Three sulfathiazole ligands (each in a ,N-binding mode) occupy three positions, while the remaining position is occupied by a disordered pyrrolidine. A pyrrolidinium is also disordered. The superoxide dismutase mimetic activity of the complex was investigated using the indirect xanthine-xanthine oxidase-nitroblue tetrazolium method and compared to that of the native enzyme.

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“…The manganese(II) mixed complexes tested in this work have been shown to compete successfully with NBT toward the superoxide ion. Although the SOD activity is not higher than some already reported, they present higher percentages of SOD activity than the [Co(quinoline) 2 (SH) 2 ] complex [26] (which it does not go beyond 60% inhibition) and appear to be promising SOD mimics.…”

Section: Resultsmentioning

confidence: 53%

“…The other two classes of SODs that contain iron or manganese have received less attention and their structures have only been recently described [18][19][20] . However, some iron 8,21,22 , manganese 8,21,23 , ruthenium 24 and cobalt 25 SOD mimics have been reported and some of them show a marked SOD activity and seem to retain it in living cells 26,27 .…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Characterization and Superoxide Dismutase Actwity of the Manganese(ii) Mixed Ligand Complexes Containing Sulfathiazole

Anacona

Dı́az

2008

J. Chil. Chem. Soc.

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Manganese(II) metal ion and sulfathiazole (Hstz) react with pyrrolidine (pyrro), piperidine (pipe) and ethylenediamine (en) to form the following mixed ligand complexes : [Mn(stz) 2 (pyrro) 2 ], [Mn(stz) 2 (pipe) 2 ] and [Mn(stz) 2 (en) 2 ] which were characterized by physicochemical and spectroscopic methods. Their spectra indicated that the sulfathiazole is probably acting as a monoanionic unidentate chelating agent. The superoxide dismutase mimetic activity of the complexes was investigated using the indirect xanthine-xanthine oxidase-nitroblue tetrazolium method and compared to that of the native enzyme.

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Cited by 24 publications

References 22 publications

Synthesis, spectral and biological investigations of 5(2′-hydroxyphenyl)-3-(4-substituted-phenyl) pyrazolinates of cobalt(II) and their addition complexes with N, P donor ligands

Synthesis, spectral and biological investigations of 5(2′-hydroxyphenyl)-3-(4-substituted-phenyl) pyrazolinates of cobalt(II) and their addition complexes with N, P donor ligands

Synthesis, crystal structure and superoxide dismutase activity of [pyrrolidinium][Co(sulfathiazole)₃(pyrrolidine)]

Synthesis, Characterization and Superoxide Dismutase Actwity of the Manganese(ii) Mixed Ligand Complexes Containing Sulfathiazole

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Untitled

Cited by 24 publications

References 22 publications

Synthesis, spectral and biological investigations of 5(2′-hydroxyphenyl)-3-(4-substituted-phenyl) pyrazolinates of cobalt(II) and their addition complexes with N, P donor ligands

Synthesis, spectral and biological investigations of 5(2′-hydroxyphenyl)-3-(4-substituted-phenyl) pyrazolinates of cobalt(II) and their addition complexes with N, P donor ligands

Synthesis, crystal structure and superoxide dismutase activity of [pyrrolidinium][Co(sulfathiazole)3(pyrrolidine)]

Synthesis, Characterization and Superoxide Dismutase Actwity of the Manganese(ii) Mixed Ligand Complexes Containing Sulfathiazole

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Synthesis, crystal structure and superoxide dismutase activity of [pyrrolidinium][Co(sulfathiazole)₃(pyrrolidine)]