An automatic flow-through system for exploration of the human bioaccessibility of endocrine disrupting compounds from microplastics

Abstract

This article reports on the first attempt towards investigating the leaching rates in the human gastrointestinal (GI) tract of plastic-borne contaminants that can be ingested accidentally using physiologically relevant body...

Bisphenols and Their Interaction with GPER-1: The Invisible Enemy Behind Breast Cancer and Its Societal Impact

“…In fact, BPA is widely present in the environment, with one of its main sources being the containers used to store water and food. As a result, the main route of exposure to BPA is through ingestion [11,43], although the possibility of dermal absorption and even inhalation has also been observed [44]. In this regard, the oral bioaccessibility of polyethylene microplastics in humans has recently been investigated, finding that phthalates and BPA show the highest fractions of gastric and intestinal bioaccessibility [11].…”

“…In this regard, the oral bioaccessibility of polyethylene microplastics in humans has recently been investigated, finding that phthalates and BPA show the highest fractions of gastric and intestinal bioaccessibility [11]. In addition, the release rates of contaminants present in plastics in the human gastrointestinal tract have been evaluated, with a significant release of BPA from high-density polyethylene (HDPE) pellets being observed [43].…”

A microscopic survey on microplastics in beverages: the case of beer, mineral water and tea

“…10 The information is important, and may have implications in filling the knowledge gap of microplastic ingestion, 4 food production and traceability 11 and health risk assessment. 12…”