Aneurysmal bone cysts in the spine, causing neurological compromise: safety and clinical efficacy of sclerotherapy utilizing sodium Tetradecyl sulfate foam

Dalili, Danoob; Parker, Jack; Mirzaian, Arya; Teh, James; Bratby, Mark; Mansour, Ramy; Reynolds, Jeremy

doi:10.1007/s00256-021-03793-w

Cited by 5 publications

(3 citation statements)

References 32 publications

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“…A meta-analysis by Cruz et al including 10 studies (294 patients) utilizing either polidocanol, Ethibloc, Doxycycline, calcitonin and steroid or calcium sulfate, reported recurrence-free survival of 94% at final follow-up (mean = 41.1, range = 23–58 months) [ 27 ]. However, 68 of 294 patients had complications including injection site induration, skin necrosis and fractures.…”

Section: Percutaneous Proceduresmentioning

confidence: 99%

“…Selective arterial embolization as primary treatment has been described for cases in hard to reach locations like the pubic bone [ 40 ], sacrum and spine [ 41 ▪ ]. In the Cruz et al study, SAE with either N-2-butyl-cyanoacrylate or PVA particles showed an 18% recurrence rate and a complication rate of only 3% including skin necrosis, sciatic nerve paresthesia and artery pseudoaneurysms [ 27 ].…”

Section: Percutaneous Proceduresmentioning

confidence: 99%

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The treatment of aneurysmal bone cysts

Geloven

Sande²,

Heijden³

2022

Current Opinion in Pediatrics

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Purpose of reviewAneurysmal bone cysts are rare, locally aggressive bone tumors. Optimal treatment of ABCs is still matter of debate as therapies including sclerotherapy, selective arterial embolization and systemic treatment with denosumab are increasingly utilized, in addition to or instead of traditional curettage. The purpose of this review is to discuss current concepts and difficulties in diagnosing and treating primary ABCs, based on latest available literature.Recent findingsIn diagnostics, multiple new fusion partners of USP-6 have been described on next-generation sequencing specifically for primary ABCs. In a recent systematic review, failure rates of percutaneous injections and surgery were comparable. In a literature review, the use of denosumab seemed effective but resulted in multiple cases of severe hypercalcemia in children.SummaryAccurately diagnosing primary ABC is crucial for treatment decisions. Curettage remains a valid treatment option, especially with adjuvant burring, autogenous bone grafting and phenolization. Percutaneous sclerotherapy represents a solid alternative to surgery, with polidocanol showing good results in larger studies. Systematic therapy with denosumab exhibits favorable results but should be reserved in the pediatric population for unresectable lesions, as it may result in severe hypercalcemia in children. When selecting a treatment option, localization, stability and safety should be considered.

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Section: Percutaneous Proceduresmentioning

confidence: 99%

Section: Percutaneous Proceduresmentioning

confidence: 99%

The treatment of aneurysmal bone cysts

Geloven

Sande²,

Heijden³

2022

Current Opinion in Pediatrics

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show abstract

“…STS is extensively used not only for fundamental studies but also for many applications in industry, including detergency and cosmetics [7], as well as pharmaceutics and medicine [8][9][10][11][12]. It is used throughout the world as a remarkable active ingredient (or additive) for foaming [13,14] and wetting agents [15], stabilizers for dispersion [16], emulsifying agents for emulsions [17], antiseptics [18], and detergents [19].…”

Section: Introductionmentioning

confidence: 99%