Impact of BMGIM Music Therapy on Emotional State in Patients with Inflammatory Bowel Disease: A Randomized Controlled Trial

Abstract

Background. Patients with inflammatory bowel disease (IBD) have a high prevalence of emotional disturbances which worsen the symptoms of the disease. As a therapeutic alternative that is part of a comprehensive care alongside medication, the Bonny Method of Guided Imagery and Music (BMGIM) music-assisted therapy has achieved promising emotional improvements in patients with chronic diseases. The objective of the study was to determine the impact of a treatment based on a BMGIM group adaptation on patients with inflammatory bowel disease (IBD) and their emotional state, therefore analyzing state of mind, quality of life, anxiety, depression, immunocompetence as a marker of well-being, and levels of acute and chronic stress. Methods. Longitudinal, prospective, quantitative, and experimental study including 43 patients with IBD divided into an intervention group (22 patients), who received eight sessions over eight weeks, and a control group (21 patients). A saliva sample was taken from each patient before and after each session in order to determine cortisol and IgA levels. Similarly, a hair sample was taken before the first and after the last session to determine the cumulative cortisol level. All molecules were quantified using the ELISA immunoassay technique. In addition, patients completed several emotional state questionnaires: HADS, MOOD, and CCVEII. Results. An improvement was observed in the following states of mind: sadness, fear, anger, and depression. No significant effect was observed in state of mind in terms of happiness or anxiety, in the levels of cortisol in hair, and in patients’ perceived quality of life. A reduction in cortisol was observed in saliva, although this did not significantly affect the IgA titer. Conclusions. BMGIM seems to improve the emotional state of patients with IBD.

Do interventions for mood improve inflammatory biomarkers in inflammatory bowel disease?: a systematic review and meta-analysis

“…This left 28 unique RCTs 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 of 1789 participants ( Fig. 1 ).…”

“…Detailed study characteristics are presented in Supplementary Table S4 . 22 arms from 20 studies trialled psychological therapy, 28 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 40 , 41 , 43 , 44 , 46 , 49 , 50 , 51 , 52 , 54 , 55 3 studies trialled antidepressants 42 , 45 , 53 and 6 arms from 5 studies trialled exercise interventions. 29 , 30 , 39 , 47 , 48 Details of intervention format and content, based on TIDieR guidance, are reported in Supplementary Table S5 .…”

“…Risk of Bias was low in 4 (14%) studies, 41 , 45 , 49 , 50 high in 18 (64%) studies 29 , 30 , 31 , 33 , 34 , 35 , 36 , 38 , 39 , 44 , 46 , 47 , 48 , 51 , 52 , 53 , 54 , 55 and showed some concerns in 6 (21%) studies. 28 , 32 , 37 , 40 , 42 , 43 For one high risk study, only an abstract was available, 35 so downgrading this study based on limited information may be unreasonable. Bias arose mostly from inadequate reporting of results: 5 (19%) studies failed to report on all inflammatory outcomes described in protocols or trial registrations 29 , 39 , 44 , 46 , 48 and 9 (33%) were not prospectively registered.…”

Influencia de la música en la neuroquímica positiva: una visión general

“…Distribución de los estudios seleccionados por revista científica 30 Revista de Investigación en Musicoterapia, 6, 2022, pp. 19-45. https://doi.org/10.15366/rim2022.6.002 de niveles el cortisol medidos, en este caso, a través de la saliva (Beck et al, 2015;March-Luján et al, 2021).…”

Comprehensive Management of Inflammatory Bowel Disease: What’s Next

“…March-Luján et al examined the impact of this method on the psychological aspects of IBD patients by using questionnaires and saliva samples of cortisol and IgA levels before and after sessions. Their results demonstrated significant improvements in psychopathologic variables of states of mind (sadness, fear, anger and depression) along with a reduction in saliva cortisol levels, indicating a positive influence on acute physiological stress levels [ 8 ].…”