2022
DOI: 10.1016/j.htct.2020.12.009
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Maternal and perinatal outcomes in pregnant women with sickle cell disease: an update

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Cited by 12 publications
(8 citation statements)
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“…This study reports that pregnancy complications are more frequent in HbSS than other genotypes. These findings are matched with the reports of several studies ( 6 , 15 , 57 , 58 ). The outcomes of pregnancy in the HbSS genotype were worse than HbAA and HbAS.…”
Section: Discussionsupporting
confidence: 92%
See 1 more Smart Citation
“…This study reports that pregnancy complications are more frequent in HbSS than other genotypes. These findings are matched with the reports of several studies ( 6 , 15 , 57 , 58 ). The outcomes of pregnancy in the HbSS genotype were worse than HbAA and HbAS.…”
Section: Discussionsupporting
confidence: 92%
“…Contrary to the existing developments in health care, especially in taking care of pregnant women over the past 4 decades, the maternal and fetal morbidity and mortality rate is high. The therapeutic interventions to improve pregnancy-related outcomes are restricted in women with SCD, particularly in those with the HbSS genotype ( 57 ).…”
Section: Discussionmentioning
confidence: 99%
“…Like perinatal mortality rates, stillbirth rates are variable from studies and constitute the burden of perinatal mortality in these pregnant women. On the other hand, authors in Brazil 20,30 reported lower stillbirths rates of 17‰ and 2.71‰ respectively. These low rates would be due to intensive follow-up of pregnant women.…”
Section: Discussionmentioning
confidence: 94%
“…According to many authors, the limit used was 28WA. 7,15,17,30 The risk of stillbirth is higher in pregnant women with sickle cell disease, [12][13][14][15]19 and these stillbirth rates, although variable depending on the country, remain high especially in countries with limited resources. Beyond the environmental and socio-economic factors, in term of physiology, pregnancy induces significant changes described above, causing chronic hypoxia and an unfavorable fetal prognosis.…”
Section: Discussionmentioning
confidence: 99%
“…Pregnancy in women with SCD results in an increased incidence of maternal and perinatal complications, such as pre-eclampsia, preterm labour, intrauterine growth restriction (IUGR), and abortions ( Sousa et al 2022 ). Additionally, pregnancy aggravates the pre-existing anaemia in women with SCD, leading to an increased incidence of severe anaemia and frequent need for blood transfusion ( Smith-Whitley 2019 ).…”
Section: Pregnancy Complicationsmentioning
confidence: 99%