337 Cerebrospinal Fluid Flow Quantification of the Cerebral Aqueduct in Children and Adults with Two-Dimentional Cine Phase-Contrast Cine MR Imaging

Fan, HC; Giiang, LH; Ty, Huang; Juan, CJ; Cy, Chen; Sj, Chen

doi:10.1136/archdischild-2012-302724.0337

Cited by 9 publications

(13 citation statements)

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“…The observation that the final volumes are much higher than normal implies that the absorptive mechanism works less well in these patients in comparison to normal subjects and it thus appears that successful ventriculostomy produces a state of compensated communicating hydrocephalus 43 . In a study of children where a third ventriculostomy was performed to treat obstruction, and the stoma was judged to be patent, the mean stroke volume across the stoma was 185 µL 44 compared to the normal aqueduct stroke volume for children of 15 µL 45 . Such a hyperdynamic flow is similar to that found in the aqueduct in communicating hydrocephalus.…”

Section: Discussionmentioning

confidence: 99%

Dilatation of the bridging cerebral cortical veins in childhood hydrocephalus suggests a malfunction of venous impedance pumping

Bateman

Subramanian

2022

Sci Rep

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Dogs with a naturally occurring form of hydrocephalus have an elevated transmural venous pressure leading to cortical vein dilatation. The purpose of this study is to discover if there is vein dilatation in childhood hydrocephalus and to estimate the pressure required to maintain any enlargement found. Children with hydrocephalus between the ages of 4 and 15 years were compared with a control group. Magnetic resonance venography (MRV) and flow quantification were performed. The arterial inflow, sagittal sinus and straight sinus venous outflow were measured and the outflow percentages compared to the inflow were calculated. The cross-sectional area of the veins were measured. There were a total of 18 children with hydrocephalus, compared to 72 age and sex matched control MRV’s and 22 control flow quantification studies. In hydrocephalus, the sagittal sinus venous return was reduced by 12.9%, but the straight sinus flow was not significantly different. The superficial territory veins were 22% larger than the controls but the vein of Galen was unchanged. There is evidence of a significant increase in the superficial vein transmural pressure in childhood hydrocephalus estimated to be approximately 4 mmHg. An impedance pump model is suggested to explain these findings.

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Section: Discussionmentioning

confidence: 99%

Dilatation of the bridging cerebral cortical veins in childhood hydrocephalus suggests a malfunction of venous impedance pumping

Bateman

Subramanian

2022

Sci Rep

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“…To evaluate pathological CSF flow, it is necessary to know the normal data. To the best of our knowledge, there are very few insufficient studies that include normal aqueductal CSF flow data of a pediatric population (12)(13)(14).…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Evaluation of aqueductal cerebrospinal fluid flow dynamics with phase-contrast cine magnetic resonance imaging in normal pediatric cases

2016

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“…Cerebrospinal fluid (CSF) surrounds the brain and spinal cord, providing support and protection against external stress [1,2]. Normal CSF pressure ranges from 5 to 15 mmHg in adults and 10 to 100 mmHg in children under six years old [2].…”

Section: Introductionmentioning

confidence: 99%

The Role of Phase-Contrast MRI in Diagnosing Cerebrospinal Fluid Flow Abnormalities

BR,

Sharma,

Polaka

et al. 2024

Cureus

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BackgroundCerebrospinal fluid (CSF) dynamics play a crucial role in maintaining the homeostasis of the central nervous system (CNS). Any disruption in CSF flow can lead to various congenital and acquired conditions, impacting neurological function and overall health. This study aims to analyze the significance of phase-contrast MRI in evaluating abnormalities in CSF flow and its diagnostic utility in various CSF-related disorders. Phase contrast MRI has emerged as a valuable tool for evaluating CSF dynamics non-invasively by examining CSF flow characteristics such as pulsatile flow patterns, hyperdynamic or hypodynamic flow, and disruptions in CSF circulation. Alterations in CSF pulsatility and stroke volume can indicate changes in intracranial compliance, vascular resistance, or CSF production and absorption rates. The findings of this study will advance our understanding of CSF physiology and its relevance in neurological pathologies, potentially leading to improved patient outcomes and management approaches.

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337 Cerebrospinal Fluid Flow Quantification of the Cerebral Aqueduct in Children and Adults with Two-Dimentional Cine Phase-Contrast Cine MR Imaging

Abstract: Abstracts diet isocaloric to the Lf (n=6) and a Sham group (n=3

Cited by 9 publications

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Dilatation of the bridging cerebral cortical veins in childhood hydrocephalus suggests a malfunction of venous impedance pumping

Dilatation of the bridging cerebral cortical veins in childhood hydrocephalus suggests a malfunction of venous impedance pumping

Evaluation of aqueductal cerebrospinal fluid flow dynamics with phase-contrast cine magnetic resonance imaging in normal pediatric cases

The Role of Phase-Contrast MRI in Diagnosing Cerebrospinal Fluid Flow Abnormalities

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