Cellulose Nanocrystals for Skin Barrier Protection by Preparing a Versatile Foundation Liquid

Abstract

Most of the foundation liquids in the market need makeup removers for cleaning, while the excessive use of makeup removers might lead to skin barrier damage, which would further lead to many kinds of dermatosis, such as skin sensitivity, facial telangiectasia, rosacea, acne, as well as various cosmetic contact dermatitis. Inspired by the protective effect of fiber-rich diet on the intestinal mucosal mechanical barrier, a novel hemp/cellulose nanocrystals (CNCs)-based foundation liquid featuring easy-wiping property has been constructed, which will effectively solve the post-makeup skin cleaning problems. In this experiment, the formula of the foundation liquid can be obtained through hemp/CNCs instead of mineral oil and titanium oxide, which are considered to have undesirable local tolerance, sensitizing potential, and are environmental pollutants, to create a moisture barrier. Industrial hemp is a hot issue in cosmetic research, and a great quantity of discarded industrial hemp stalk is available to be used to produce hemp/CNCs through grinding and acidification. The graft technique is adapted to obtain hemp/CNCs-g-polylactic acid (PLA). By replacing the hydroxyl group on the side of hemp/CNCs, hemp/CNCs-g-PLA reduces the intermolecular hydrogen bonding, resulting in a higher dispersion in the oil phase. The hemp/CNCs-g-PLA has excellent performance in terms of biological compatibility, water resistance, and non-penetration into the skin. With basic features of a foundation liquid to alleviate discoloration, age spots, and skin roughness, the foundation liquid based on hemp/CNCs-g-PLA provides a novel characteristic of easy-wiping, which helps to avoid the damage to the skin barrier caused by excessive cleansing.

Nanocelluloses as skin biocompatible materials for skincare, cosmetics, and healthcare: Formulations, regulations, and emerging applications

“…Due to their high flexibility, the CNFs sheets favorably serve as face masks providing a good fitting and comfortable feeling on the skin and lips (Perugini et al, 2018). Moreover, peeling films can be formed as a separate freestanding layer with a good affinity to the skin (Tang et al, 2021). The formation of a coherent film with CNFs is enhanced by avoiding cracking and the film remains transparent due to the thin fibril diameters.…”

“…Aqueous CNCs suspensions are compatible with skincare products and are added at a typical dilution factor of 50. Inspired by the protective effect of a fiber-rich diet on the intestinal mucosal mechanical barrier, a novel hemp/CNCs-based foundation liquid has been recently formulated (Figure 6), which effectively solves the post-makeup skin cleaning problems (Tang et al, 2021). The basic features provide easy removal of the foundation through simple wiping, which avoids skin damage caused by excessive cleansing.…”

Self-Assembly of Cellulose Nanocrystals and Organic Colored Pigments as Reinforcement Matrix of Lipstick for Enhancing SPF

“…Inspired by plant pigmentation as natural filters to protect themselves against overexposure to UV, binding of AN to CNC was designed and prepared. Our previous study has applied CNC in foundation liquid [19]. Herein, we formulated traditional rouge from nontransparent minerals and plants such as clove and cinnabar (Figure 1(a)).…”

“…CNC extracted using acid hydrolysis of hemp stem was added into anthocyanin liquid at 0.15 g/mL and then stirred at 60 °C for 30 min. Then, the cellulose was centrifuged at 2000 rpm for 15 min [19]. The precipitation was grafting CNC-AN homogenate and eventually freeze-dried.…”

Natural Biomaterials from Biodiversity for Healthcare Applications

“…Recently, bacterial cellulose has gained interest as an ecofriendly alternative to synthetic polymers in the cosmetic industry. [210,249] It is mainly used as a 3D support matrix for skinmasks and delivery of bioactive substances. Regarding the effects of the silk sericin-releasing bacterial nanocellulose gel on the skin, the gel was less adhesive than the commercially available paper mask; however, it showed good adhesion to the skin and improved skin moisture (hydration effect) comparable to those of the vegetable extract mask formulation.…”