The prevalence and associated factors of nonadherence to antihypertensive medication in secondary healthcare

Pinhati, Renata Romanholi; Ferreira, Renato Erothildes; Carminatti, Moisés; Tavares, Paula Liziero; Marsicano, Elisa Oliveira; Sertório, Emiliana Spadarotto; Colugnati, Fernando Antônio Basile; Paula, Rogério Baumgratz de; Sanders-Pinheiro, Hélady

doi:10.1007/s11255-020-02755-w

Cited by 5 publications

(5 citation statements)

References 35 publications

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“…Seven of the included studies reported a consistent trend: a higher number of prescribed hypertensive medications correlated with lower medication adherence. 13,16,20,23,24,28,29 This aligns with robust evidence from a nationwide study conducted in the Republic of Korea, which aimed to investigate the impact of the number of medications and age on antihypertensive medication adherence. The study demonstrated a significant decline in adherence when nine or more total medications were taken, irrespective of age.…”

Section: Discussionsupporting

confidence: 56%

“…38 Similarly, five studies included in our review established a substantial association between financial status and medication adherence. 13,16,20,21,28 Specifically, a study by Macquart de Terline et al demonstrated that older hypertensive patients with a lower wealth index were more likely to exhibit lower adherence to antihypertensive medications. 13 Likewise, Akkara et al identified that individuals with a low socioeconomic level were seven times more likely to demonstrate poor compliance with medication use compared to those with a high socioeconomic level.…”

Section: Selfefficacymentioning

confidence: 99%

“…[43][44][45] Two studies included in our review specifically identified health literacy as a predictive factor for medication adherence among older adults with hypertension. 18,28 First, the study by Heizomi et al explored gender-based associations of health literacy with self-reported medication adherence among patients with primary hypertension, revealing a significant correlation between health literacy and medication adherence. 18 Similarly, a cross-sectional study by Pinhati et al reported that nonadherence was associated with low health literacy.…”

mentioning

confidence: 99%

“…18 Similarly, a cross-sectional study by Pinhati et al reported that nonadherence was associated with low health literacy. 28 In light of these findings, it is recommended that the association between health literacy and medication adherence be further confirmed through interventional studies. Such confirmation would solidify health literacy as a formal mitigating strategy for medication adherence and other public health goals.…”

mentioning

confidence: 99%

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Medication Adherence of Older Adults with Hypertension: A Systematic Review

Ruksakulpiwat,

Schiltz,

Irani

et al. 2024

PPA

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Hypertension (HTN) significantly increases the risk of stroke and heart disease, which are the leading causes of death and disability globally, particularly among older adults. Antihypertensive medication is a proven treatment for blood pressure control and preventing complications. However, medication adherence rates in older adults with HTN are low. In this review, we systematically identified factors influencing medication adherence in older adults with HTN. Methods: We applied the PRISMA guidelines and conducted systematic searches on PubMed, MEDLINE, and Google Scholar in July 2022 to identify preliminary studies reporting factors influencing medication adherence among older adults with HTN. The convergent integrated analysis framework suggested by the Joanna Briggs Institute for systematic reviews was adopted for data synthesis. Results: Initially, 448 articles were identified, and after title and abstract screening, 16 articles qualified for full-text review. During this phase, three articles were excluded for reporting on irrelevant populations or focusing on issues beyond the review's aim, leaving thirteen studies in the final review. After data synthesis, fifteen themes were extracted from the key findings of the included studies. The most prevalent themes included the number of medications used (53.9%, n=7 studies), financial status (38.5%, n=5), sex (38.5%, n=5), age (30.1%, n=4), duration of disease (23.1%, n=3), comorbidities (23.1%, n=3), and health compliance (23.1%, n=3). Other themes, such as education, health literacy, health belief, medication belief, perception of illness, patient-physician relationship, selfefficacy, and social support, were also identified. Conclusion:The findings of this review highlight critical areas for developing innovative, evidence-based programs to improve medication adherence in hypertensive older adults. Insights from this review can contribute to improving medication adherence and preventing future health complications.

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Section: Discussionsupporting

confidence: 56%

Section: Selfefficacymentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Medication Adherence of Older Adults with Hypertension: A Systematic Review

Ruksakulpiwat,

Schiltz,

Irani

et al. 2024

PPA

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“… 14 Previous studies have found factors that impact medication adherence. For example, financial problems, 15 , 16 education, 17 , 18 social support, 19–21 health literacy, 22 , 23 or sociodemographic factors such as age 24 , 25 and gender. 22 , 24 , 26 Thus, it is essential to understand the factors that influence medication adherence comprehensively.…”

Section: Introductionmentioning

confidence: 99%

Utilizing Social Determinants of Health Model to Understand Barriers to Medication Adherence in Patients with Ischemic Stroke: A Systematic Review

Ruksakulpiwat,

Benjasirisan,

Ding

et al. 2023

PPA

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Introduction Ischemic strokes and their recurrence create an immense disease burden globally. Therefore, preventing recurrent strokes by promoting medication adherence is crucial to reduce morbidity and mortality. In addition, understanding the barriers to medication adherence related to the social determinants of health (SDoH) could promote equity among persons with ischemic stroke. Objective To explore the barriers to medication adherence among patients with ischemic stroke through the SDoH. Methods This systematic review included studies published between January 2018 and December 2022 identified through PubMed, MEDLINE, Web of Science, and CINAHL Plus Full Text. The descriptions of the studies were systematically summarized and discussed based on the SDoH from the US Healthy People 2030 initiative. Results Eight studies met the inclusion criteria and were included in this review. The most common barrier to adherence was inappropriate medication beliefs, medication side effects, and patient-physician relationship, which relate to the dimensions of healthcare access and quality. Health literacy and health perception, dependent on education access and quality, frequently influenced adherence. Other social determinants, such as financial strain and social and community context, were found to alter adherence behaviors. No study addressed the neighborhood and built environment domain. We found that cognitive impairment is another factor that impacts adherence outcomes among stroke patients. Conclusion Multifaceted approaches are needed to address the SDoH to improve medication adherence among patients with ischemic stroke. This review emphasized strategies, including patient education, provider-patient communication, social support, health literacy, technology, and policy advocacy to enhance adherence.

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Salt taste threshold and contributory factors of chronic kidney disease patients: a cross-sectional study

Liao²,

Liao³

et al. 2022

Int Urol Nephrol

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The prevalence and associated factors of nonadherence to antihypertensive medication in secondary healthcare

Cited by 5 publications

References 35 publications

Medication Adherence of Older Adults with Hypertension: A Systematic Review

Medication Adherence of Older Adults with Hypertension: A Systematic Review

Utilizing Social Determinants of Health Model to Understand Barriers to Medication Adherence in Patients with Ischemic Stroke: A Systematic Review

Salt taste threshold and contributory factors of chronic kidney disease patients: a cross-sectional study

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