Colorimetric determination of cysteine based on inhibition of GSH-Au/Pt NCs as peroxidase mimic

Enhancing the catalytic performance of MOF-polymer@AuNP-based nanozymes for colorimetric detection of serum l-cysteine

“…L-Cys is an important amino acid in the human system that affects various physiological activities. 23 However, fluctuation in L-Cys levels can have harmful effects on various tissues. 22,24,25 Therefore, quantitative and qualitative testing for L-Cys is increasingly important for human health.…”

Engineering single-atom catalysts toward biomedical applications

“…This is exactly why great effort has been recently devoted to design the SACs as one of the promising alternatives to conventional nanocatalysts. For example, by carefully sorting out the relevant literature about the Pt-based catalysts at different scales, 26,243,244 we find that the POD-like catalytic activity of Pt-SACs was above 1.5 and 4.2 times higher than that of Pt nanoclusters and Pt nanoparticles, respectively (Fig. 14a-c).…”

Michael addition–elimination–cyclization based turn-on fluorescence (MADELCY TOF) probes for cellular cysteine imaging and estimation of blood serum cysteine and aminoacylase-1

“…Traditionally, the most commonly used approaches for Cys detection in biological samples have relied on analytical platforms including HPLC, 23–26 electrochemical and capillary electrophoresis, 27–30 and calorimetry, 31–34 whereas those for estimating ACY-1 levels have employed mass spectrometry and ELISA. 18,19,35,36 These approaches entail the use of expensive instrumentation and technically convoluted experimental procedures that limit their widespread use.…”

“…19 Therefore, approaches for the precise estimation of the cellular and blood serum ACY-1 are being actively pursued for the early diagnoses of these diseased states and monitoring their progression. [18][19][20][21][22] Traditionally, the most commonly used approaches for Cys detection in biological samples have relied on analytical platforms including HPLC, [23][24][25][26] electrochemical and capillary electrophoresis, [27][28][29][30] and calorimetry, [31][32][33][34] whereas those for estimating ACY-1 levels have employed mass spectrometry and ELISA. 18,19,35,36 These approaches entail the use of expensive instrumentation and technically convoluted experimental procedures that limit their widespread use.…”