Platelet-rich plasma has a place in the treatment of androgenetic alopecia

Hooper, Deirdre

doi:10.1016/j.jaad.2020.11.030

Cited by 2 publications

(3 citation statements)

References 5 publications

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“…Many clinical studies have shown that PRP is beneficial for treating hair loss. 13,14 However, there has been no unified standard for the preparation process of PRP. Due to the multifold enrichment of platelets that secrete GFs after PRP injection, the heterogeneity of GFs may lead to inconsistent clinical responses.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of platelet‐rich plasma plus basic fibroblast growth factor combined with minoxidil in the treatment of androgenetic alopecia: A randomized controlled trial

Liu

Chen

et al. 2023

J of Cosmetic Dermatology

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Background Platelet‐rich plasma plus basic fibroblast growth factor (PRPF) has been confirmed to be a safe and valuable therapy for androgenetic alopecia (AGA). However, the efficacy of PRPF combined with minoxidil treatment remains unknown. Objective To assess the efficacy of combined PRPF and minoxidil treatment for AGA. Methods In this prospective, randomized controlled trial, 75 patients with AGA were randomly divided into three groups and were administered the following treatments: Group 1, direct intradermal PRPF injection; Group 2, topical minoxidil 5% twice daily; and Group 3, PRPF injection combined with minoxidil. The PRPF injection was performed three times, 1 month apart. Hair growth parameters were evaluated using a trichoscope until the sixth month of the study. Patient satisfaction and side effects were recorded during the follow‐up. Results All patients showed improvements (p < 0.05) in hair count, terminal hair, and decrease in telogen hair ratio after treatment. The efficacy of PRPF complex therapy revealed significant improvements (p < 0.05) in hair count, terminal hair and growth rate, compared with monotherapy. Limitations Small sample size, short follow‐up time and lack of quantification of GFs in PRPF. Conclusion The effect of complex therapy exceed both the effects of PRPF monotherapy and minoxidil treatment, which can be a beneficial AGA treatment strategy.

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Section: Discussionmentioning

confidence: 99%

“…Owing to the limited effective treatment of AGA, PRP is gradually becoming an effective alternative therapy. Many clinical studies have shown that PRP is beneficial for treating hair loss 13,14 . However, there has been no unified standard for the preparation process of PRP.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of platelet‐rich plasma plus basic fibroblast growth factor combined with minoxidil in the treatment of androgenetic alopecia: A randomized controlled trial

Liu

Chen

et al. 2023

J of Cosmetic Dermatology

View full text Add to dashboard Cite

show abstract

“…1 , 2 At present, there are many treatments for AGA, such as the oral administration of finasteride tablets, the topical application of minoxidil and hair transplant surgery, etc. 3 In recent years, the injection of platelet‐rich plasma (PRP) 4 , 5 or autologous fat 6 and even novel drug delivery systems have emerged. 7 Although the treatment methods are constantly improving, AGA can still not be cured effectively.…”

Section: Introductionmentioning

confidence: 99%