The role of dietary salt and alcohol use reduction in the management of hypertension

Wake, Addisu Dabi

doi:10.1080/14779072.2021.1850266

Cited by 11 publications

(14 citation statements)

References 164 publications

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“…Alcohol and salt are the most important causes for HBP and increased cardiovascular risk worldwide [ 30 ]. Chronic alcohol and salt abuse is the cause of cardiovascular, renal, and liver dysfunction as well as oxidative stress and dyslipidemias associated with atherosclerosis that contributes to the pathogenesis of hypertension.…”

Section: Discussionmentioning

confidence: 99%

“…According to Wake (2021), alcohol or its metabolic derivatives act on the cardiovascular system or on the blood pressure regulation systems. This is achieved through a decrease in nitric oxide in the vascular endothelium due to inhibition of endothelial nitric oxide synthase [ 30 ]. This leads to inflammatory/oxidative damage to the vascular endothelium and therefore to vasoconstriction which increases vascular resistance and leads to HBP [ 30 ].…”

Section: Discussionmentioning

confidence: 99%

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Preventive Potential of the Aqueous Extract of the Mixture of Bidens pilosa (Asteraceae) and Cymbopogon citratus (Poaceae) Aerial Parts on Hypertension Induced by a Chronic Salt and Alcohol Consumption on the Rats

Tcheutchoua

Bilanda

Dzeufiet

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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High blood pressure (HBP) is currently one of the main risk factors for cardiovascular and kidney diseases. Nowadays, populations make extensive use of alternative medicine for their health problems. Bidens pilosa (B. pilosa) and Cymbopogon citratus (C. citratus) are used individually in the traditional treatment of cardiovascular disorders. This study assessed the effects of the mixture of these two plants aqueous extract on HBP in rats. Male rats (42) were divided into 7 groups of 6 rats each. Normotensive rats received only distilled water and formed group 1. The other animals received ethanol + salt preceded by distilled water (10 mL/kg; group 2) and spironolactone (10 mg/kg; group 3); the aqueous extracts of the mixture (100 and 200 mg/kg; groups 4 and 5) isolated plants B. pilosa (200 mg/kg; group 6) and C. citratus (200 mg/kg; group 7). Animals were treated for 7 weeks during which water consumption and urine volume were assessed; then, hemodynamic parameters were recorded, and rats were sacrificed. Serum and some organs (liver, kidney, heart, and aorta) were used to evaluate biochemical parameters. Ingestion of ethanol + salt leads to a significant increase in urinary volume and water intake that were significantly prevented by the extracts from the mixture and isolated plants. Ethanol + salt solution significantly increased the blood pressure, heart rate, triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-chol), very-low-density lipoprotein cholesterol (VLDL-chol), atherogenic indices, liver and kidney function parameters, and malondialdehyde (MDA) levels. However, the levels of high-density lipoprotein cholesterol (HDL-chol), albumin, reduced glutathione (GSH), catalase, and superoxide dismutase (SOD) activity were significantly reduced. The extracts of the mixture and isolated plants significantly prevented all these variations with a more pronounced action for the lowest dose of the mixture on the lipid profile, oxidative stress, and kidney function. These observations confirm the beneficial effects of B. pilosa and C. citratus to manage hypertension.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Preventive Potential of the Aqueous Extract of the Mixture of Bidens pilosa (Asteraceae) and Cymbopogon citratus (Poaceae) Aerial Parts on Hypertension Induced by a Chronic Salt and Alcohol Consumption on the Rats

Tcheutchoua

Bilanda

Dzeufiet

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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“…A decrease in the frequency of alcohol consumption could lead to a considerable depletion in the risk of all-cause and cardiovascular death for older people with hypertension [17,18]. Moreover, this would be more important after lockdown, given that Browne et al [19] reported that older people with hypertension would be more vulnerable to a cardiometabolic disturbance cascade during the COVID-19 pandemic, which may potentially increase their risk of cardiovascular and metabolic diseases.…”

Section: E P U B a H E A D O F P R I N T 10mentioning

confidence: 99%

The medium-term consequences of a COVID-19 lockdown on lifestyle among Spanish older people with hypertension, pulmonary disease, cardiovascular disease, musculoskeletal disease, depression, and cancer

et al. 2022

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Funding SourcesThis research is part of the Project funded by the Junta de Comunidades de Castilla-La Mancha, entitled: "Impacto del confinamiento domiciliario del COVID-19 sobre la salud de los adultos mayores: Un experimento natural en España." (Reference:2020/9024). The TSHA and the EXERNET cohorts were supported by the Biomedical Research Networking Center on Frailty and Healthy Aging (CIBERFES) and FEDER funds from the European Union

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“…Excessive intake will cause diseases such as weakened immunity, hypertension, arteriosclerosis, cerebral infarction, etc. [18][19][20]. A severely reduced Cl − intake can have negative impacts such as chronic heart failure, chronic kidney disease, liver cirrhosis, and so on [21][22][23][24].…”

Section: Sources and Hazards Of Chloride Ionmentioning

confidence: 99%

Review of Chloride Ion Detection Technology in Water

Hu²,

Liu

et al. 2021

Applied Sciences

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The chloride ion (Cl−) is a type of anion which is commonly found in the environment and has important physiological functions and industrial uses. However, a high content of Cl− in water will do harm to the ecological environment, human health and industrial production. It is of great significance to strictly monitor the Cl− content in water. Following the recent development of society and industry, large amounts of domestic sewage and industrial sewage are discharged into the environment, which results in the water becoming seriously polluted by Cl−. The detection of Cl− has gradually become a research focus. This paper introduces the harm of Cl− pollution in the environment and summarizes various Cl− detection methods, including the volumetric method, spectrophotometry method, electrochemical method, ion chromatography, paper-based microfluidic technology, fluorescent molecular probe, and flow injection. The principle and application of each technology are described; their advantages, disadvantages, and applicability are discussed. To goal of this research is to find a more simple, rapid, environmental protection and strong anti-interference detection technology of Cl−.

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The role of dietary salt and alcohol use reduction in the management of hypertension

Cited by 11 publications

References 164 publications

Preventive Potential of the Aqueous Extract of the Mixture of Bidens pilosa (Asteraceae) and Cymbopogon citratus (Poaceae) Aerial Parts on Hypertension Induced by a Chronic Salt and Alcohol Consumption on the Rats

Preventive Potential of the Aqueous Extract of the Mixture of Bidens pilosa (Asteraceae) and Cymbopogon citratus (Poaceae) Aerial Parts on Hypertension Induced by a Chronic Salt and Alcohol Consumption on the Rats

The medium-term consequences of a COVID-19 lockdown on lifestyle among Spanish older people with hypertension, pulmonary disease, cardiovascular disease, musculoskeletal disease, depression, and cancer

Review of Chloride Ion Detection Technology in Water

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