Physio-biochemical, metabolic nitrogen excretion and ion-regulatory assessment in largemouth bass (Micropterus salmoides) following exposure to high environmental iron

Egnew, Nathan; Renukdas, Nilima; Romano, Nicholas; Kelly, Anita M.; Lohakare, J. D.; Bishop, West M.; Lochmann, Rebecca; Sinha, Amit Kumar

doi:10.1016/j.ecoenv.2020.111526

Cited by 7 publications

(3 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Considering the evaluation of glycogen in groups treated with FeCl 3 , the data obtained in the present study indicated a decrease in glycogen content at 14 days (Figure 5C), as well as in the study of Egnew et al (2021), 50 in which there was a decrease in the amount of hepatic glycogen in fish of the species Micropterus salmoides in chronic exposure to high concentration of Fe 3+ these authors considered that the glycogen reserves are the preferential metabolic fuel used in the maintenance of homeostasis to provide the energy demands facing a potentially toxic agent. In this sense, the present study indicated that the longer the time of exposure to toxic agents, the higher were the levels of depletion.…”

Section: Resultssupporting

confidence: 90%

Co‐exposure of iron oxide nanoparticles and glyphosate‐based herbicide promote liver toxicity in guppy (Poecilia reticulata): A histochemical and ultrastructural approach

Martins

Lima-Faria

Guimarães

et al. 2022

Environmental Toxicology

View full text Add to dashboard Cite

Citrate functionalized iron oxide nanoparticles (IONPs) are employed for various purposes-including environmental remediation but the interaction of IONPs with aquatic contaminants is poorly understood. Among those, glyphosate-based herbicides are toxic and affect target organs such as the liver. Evaluations of livers of female Poecilia reticulata by exposures to IONPs at a concentration of 0.3 mg/L were performed with association to: (1) 0.65 mg of glyphosate per litter and (2) 1.3 mg of glyphosate per litter of Roundup Original, and (3) glyphosate P.A at 0.65 mg/L. These associations were carried out progressively, after 7, 14, and 21 days. We detected circulatory disturbances, inflammatory responses, activation of the immune system, regressive changes, and progressive responses with changes in the connective tissue and decreased glycogen reserve from days 14 to 21. Ultrastructural changes in the Disse space and microvilli of hepatocytes indicated decreased contact surface area.In general, the damage was time and concentration dependent, increasing from 7 to 14 days and tending to stabilize from 14 to 21 days. Therefore, herbicide-associated IONPs functioned as xenobiotics inducing intense cellular detoxification processes and activation of hepatic immune responses.

show abstract

Section: Resultssupporting

confidence: 90%

Co‐exposure of iron oxide nanoparticles and glyphosate‐based herbicide promote liver toxicity in guppy (Poecilia reticulata): A histochemical and ultrastructural approach

Martins

Lima-Faria

Guimarães

et al. 2022

Environmental Toxicology

View full text Add to dashboard Cite

show abstract

“…Plasma total iron was determined using an Atomic Absorption Spectrometer (AAS) (Thermo Scienti c iCE 3000 series; USA) following protocols described by Egnew et al (2021). Plasma samples were obtained from heparinized blood collected as described in the previous section by centrifuging at 800 X g for 15…”

Section: Total Plasma Ironmentioning

confidence: 99%

Elevated concentrations of organic and inorganic forms of iron in plant-based diets for channel catfish prevent anemia but damage liver and intestine, respectively, without impacting growth performance

Buyinza

Lochmann

Sinha

et al. 2023

Fish Physiol Biochem

Self Cite

View full text Add to dashboard Cite

We compared the effects of using inorganic and organic forms of iron in plant-based diets on cat sh performance in a feeding trial with cat sh ngerlings (initial weight = 6.1 ± 0.2 g). Five diets supplemented with 0 (basal), 125, 250 mg Fe/kg of either FeSO 4 or iron methionine were formulated. Fish weight gain, feed conversion ratio, hepatosomatic index, and survival were similar among diets. Fish plasma and intestine iron concentration was similar among diets. Fish whole-body total lipid, protein, and dry matter were similar among diets. Ash content was higher in sh fed the basal diet than in other diets. Total liver iron concentration was higher in sh fed diets supplemented with 250 mg Fe/kg in both iron forms than other diets. Hematological parameters were similar among diets. Liver necrosis, in ammation, and vacuolization were highest in sh fed the diet supplemented with 250 mg Fe/kg from organic iron, followed by those fed diets with 250 mg Fe/kg from inorganic iron. Inorganic iron-supplemented diets caused more intestinal in ammation characterized by increased in ammatory cells, swelling of the villi, and thicker lamina propria than the organic iron-supplemented diets or the basal diet. Organic iron at 250 mg/kg resulted in a 0.143$/kg increase in feed cost. Latent iron de ciency and initial signs of anemia developed in cat sh fed the basal diet. Supplemental iron from either form prevented iron de ciency in sh. Organic iron at 125 mg/kg optimized sh performance at a cost comparable to that of sh fed other diets, but without overt negative effects.

show abstract

“…First, elevated concentrations of toxic metals (e.g., Fe, Zn, Ni, Cu, Cd) can be directly absorbed from the water column by aquatic biota, yielding direct toxic effects on producers and consumers. The accumulation of these metals in fish gills, liver, and muscle tissue is known to structurally impair gills, damage DNA, and decrease growth and survival 19,30 . Ultimately, a complete water quality assessment could ascertain if trace metal concentrations exceeded acute and chronic exposure levels for a range of aquatic biota based on water pH, hardness, and DOC concentration 31,32 .…”

Section: Biological Consequences Of Trace Metal Mobilizationmentioning

confidence: 99%

Metal mobilization from thawing permafrost to aquatic ecosystems is driving rusting of Arctic streams

O’Donnell,

Carey,

Koch

et al. 2024

Commun Earth Environ

View full text Add to dashboard Cite

Climate change in the Arctic is altering watershed hydrologic processes and biogeochemistry. Here, we present an emergent threat to Arctic watersheds based on observations from 75 streams in Alaska’s Brooks Range that recently turned orange, reflecting increased loading of iron and toxic metals. Using remote sensing, we constrain the timing of stream discoloration to the last 10 years, a period of rapid warming and snowfall, suggesting impairment is likely due to permafrost thaw. Thawing permafrost can foster chemical weathering of minerals, microbial reduction of soil iron, and groundwater transport of metals to streams. Compared to clear reference streams, orange streams have lower pH, higher turbidity, and higher sulfate, iron, and trace metal concentrations, supporting sulfide mineral weathering as a primary mobilization process. Stream discoloration was associated with dramatic declines in macroinvertebrate diversity and fish abundance. These findings have considerable implications for drinking water supplies and subsistence fisheries in rural Alaska.

show abstract

Physio-biochemical, metabolic nitrogen excretion and ion-regulatory assessment in largemouth bass (Micropterus salmoides) following exposure to high environmental iron

Cited by 7 publications

References 39 publications

Co‐exposure of iron oxide nanoparticles and glyphosate‐based herbicide promote liver toxicity in guppy (Poecilia reticulata): A histochemical and ultrastructural approach

Co‐exposure of iron oxide nanoparticles and glyphosate‐based herbicide promote liver toxicity in guppy (Poecilia reticulata): A histochemical and ultrastructural approach

Elevated concentrations of organic and inorganic forms of iron in plant-based diets for channel catfish prevent anemia but damage liver and intestine, respectively, without impacting growth performance

Metal mobilization from thawing permafrost to aquatic ecosystems is driving rusting of Arctic streams

Contact Info

Product

Resources

About