Metabolome classification via GC/MS and UHPLC/MS of olive fruit varieties grown in Egypt reveal pickling process impact on their composition

Fayek, Nesrin M.; Farag, Mohamed A.; Saber, Fatema R.

doi:10.1016/j.foodchem.2020.127861

Cited by 27 publications

(13 citation statements)

References 30 publications

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“…Similar to other '-omics' disciplines, metabolomics uses different analytical platforms, separately or in combination (two or more techniques) [32,42]. Although several analytical platforms are employed in metabolomics studies, including FT-IR spectroscopy [43][44][45], HPLC [46,47], NMR spectroscopy [48][49][50][51][52][53], and MS [54][55][56][57] combined with gas or liquid chromatography [58][59][60][61][62], MS and NMR are the most common approaches [3,50,[63][64][65]. There is no single optimum analytical technique that can elucidate all metabolites equally.…”

Section: Analytical Techniques In Metabolomicsmentioning

confidence: 99%

Pharmacometabolomics: A New Horizon in Personalized Medicine

Emwas¹,

Szczepski

McKay³

et al. 2021

Metabolomics - Methodology and Applications in Medical Sciences and Life Sciences

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Pharmacology is the predominant first-line treatment for most pathologies. However, various factors, such as genetics, gender, diet, and health status, significantly influence the efficacy of drugs in different patients, sometimes with fatal consequences. Personalized diagnosis substantially improves treatment efficacy but requires a more comprehensive process for health assessment. Pharmacometabolomics combines metabolomic, genomic, transcriptomic and proteomic approaches and therefore offers data that other analytical methods cannot provide. In this way, pharmacometabolomics more accurately guides medical professionals in predicting an individual’s response to selected drugs. In this chapter, we discuss the potentials and the advantages of metabolomics approaches for designing innovative and personalized drug treatments.

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Section: Analytical Techniques In Metabolomicsmentioning

confidence: 99%

Pharmacometabolomics: A New Horizon in Personalized Medicine

Emwas¹,

Szczepski

McKay³

et al. 2021

Metabolomics - Methodology and Applications in Medical Sciences and Life Sciences

View full text Add to dashboard Cite

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“…Olive, a common tree plant in Mediterranean climates, belongs to the Olive genus in the Burseraceae family (Fan et al ., 2022). Olive fruit and its processed products are recognised as functional foods because of their bioactive components, which include fatty acids, polyphenols (such as tyrosol, hydroxytyrosol, hydroxytyrosol acetate, 3,4‐dihydroxyphenyl glycol and oleourine protein), and vitamins (especially α‐tocopherol) (Fayek et al ., 2021). The health benefits of olive polyphenols include antioxidant, anti‐inflammatory, anti‐allergic, antidiabetic, antimutagenic and antibacterial effects (Dziki et al ., 2014; Quirós‐Sauceda et al ., 2014; Wojdyło et al ., 2014).…”

Section: Introductionmentioning

confidence: 99%

Influences of lactic acid bacterial fermentation on the physicochemical properties and biological activities of olive phenols

Lin,

Xiong,

Peng

2024

Int J of Food Sci Tech

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SummaryOlives are a popular fruit in China, often consumed as olive juice beverages due to their richness in phenolic compounds. Fermentation by lactic acid bacteria has been shown to enhance the nutritional and health benefits of fruits and vegetables. However, the effect of fermentation on olive phenolics during in vitro‐simulated digestion has not yet been reported. This study aimed to explore changes in total polyphenol content, antioxidant capacity, xanthine oxidase inhibition, and effects on simulated digestion of olive phenolics before and after fermentation of olive fruits. Fermentation increased the total phenolic content, antioxidant capacity and XO inhibition activity of olive phenolics and these differences were maintained after simulated gastrointestinal digestion. This means that fermented olives should have greater biological activity in general as well as greater human health benefits. Phenolic extracts of fermented olives contained six phenolics with a higher content than unfermented olives after simulated gastrointestinal digestion. These findings help to improve understanding of the benefits of fermentation for producing health‐beneficial functional foods from fruits and vegetables that are rich in phenolic compounds.

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“…under low-N conditions, respectively. Fayek et al (2021), Huang et al (2021), and X. Zhang et al (2021) introduced the application of metabolomics in the study of metabolic characteristics and quality prediction during crop production, including citrus, wine, and olives.…”

Section: Introductionmentioning

confidence: 99%

Effects of different nitrogen application rates on the quality and metabolomics of cigar tobacco

Yang

et al. 2022

Agronomy Journal

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Nitrogen (N) is an essential nutrient element in plants that participates in physiological and biochemical regulation. However, the effects of different N applications on cigar tobacco (Nicotiana tabacum L.) growth are not well known. In this study, the differences in agronomical characteristics and nutritional quality of cigar tobacco leaves at the mature and curing stages under different exogenous N applications were explored. The dry matter accumulation of cigar tobacco leaves increased with increasing N application rates. In the two stages, the nutritional quality of cigar tobacco leaves was similar, but the concentrations of N and Cl were increased. To understand the effect of exogenous N on cigar tobacco metabolism, untargeted metabolomics was applied. Six significantly differential metabolites, including phenylalanine, phosphoserine, glutamate, oxoproline, succinylhomoserine, and homoserine, were identified, and the main metabolic pathways around the tricarboxylic acid cycle were identified. These results provide a better understanding of the effects of exogenous N application on the physiological, biochemical, and metabolic processes of cigar tobacco and provide a reference for fertilization control in cigar tobacco production.

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Metabolome classification via GC/MS and UHPLC/MS of olive fruit varieties grown in Egypt reveal pickling process impact on their composition

Cited by 27 publications

References 30 publications

Pharmacometabolomics: A New Horizon in Personalized Medicine

Pharmacometabolomics: A New Horizon in Personalized Medicine

Influences of lactic acid bacterial fermentation on the physicochemical properties and biological activities of olive phenols

Effects of different nitrogen application rates on the quality and metabolomics of cigar tobacco

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