Identification of active compound combination contributing to anti-inflammatory activity of Xiao-Cheng-Qi Decoction via human intestinal bacterial metabolism

Liu, Xingyan; Li, Li; Li, Xueqing; Yu, Boyang; Liu, Jihua

doi:10.1016/s1875-5364(18)30088-8

Cited by 4 publications

(1 citation statement)

References 49 publications

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“…to promote peristalsis, and increasing the butyl aminobenzene level after metabolism (74). In addition, Liu et al suggested that the anti-inflammatory activity of Xiao-Cheng-Qi-Tang was at least partially mediated by intestinal bacterial metabolism (75).…”

Section: Traditional Herbal Formulationsmentioning

confidence: 99%

Considering traditional Chinese medicine as adjunct therapy in the management of chronic constipation by regulating intestinal flora

Wang,

Qiu,

Chen

et al. 2024

BST

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Chronic constipation is one of the most common gastrointestinal disorders worldwide. Due to changes in diet, lifestyle, and the aging population, the incidence of chronic constipation has increased year by year. It has had an impact on daily life and poses a considerable economic burden. Nowadays, many patients with chronic constipation try to seek help from complementary and alternative therapies, and traditional Chinese medicine (TCM) is often their choice. The intestinal flora play an important role in the pathogenesis of constipation by affecting the body's metabolism, secretion, and immunity. Regulating the intestinal flora and optimizing its composition might become an important prevention and treatment for chronic constipation. TCM has unique advantages in regulating the imbalance of intestinal flora, and its curative effect is precise. Therefore, we reviewed the relationship between intestinal flora and chronic constipation as well as advances in research on TCM as adjunct therapy in the management of chronic constipation by regulating intestinal flora. Some single Chinese herbs and their active ingredients (e.g., Rheum palmatum, Radix Astragalus, and Cistanche deserticola), some traditional herbal formulations (e.g., Jichuan decoction, Zengye decoction, and Zhizhu decoction) and some Chinese patent medicines (e.g., Maren pills and Shouhui Tongbian capsules) that are commonly used to treat chronic constipation by regulating intestinal flora are highlighted and summarized. Moreover, some external forms of TCM, and especially acupuncture, have also been found to improve intestinal movement and alleviate constipation symptoms by regulating intestinal flora. We hope this review can contribute to an understanding of TCM as an adjunct therapy for chronic constipation and that it can provide useful information for the development of more effective constipation therapies.

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Section: Traditional Herbal Formulationsmentioning

confidence: 99%

Considering traditional Chinese medicine as adjunct therapy in the management of chronic constipation by regulating intestinal flora

Wang,

Qiu,

Chen

et al. 2024

BST

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Diosmin: A promising phytochemical for functional foods, nutraceuticals and cancer therapy

Rahman,

Talha Khalil,

Ahsan Shahid

et al. 2024

Food Science & Nutrition

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Diosmin, a potent bioflavonoid derived from citrus fruits, has gained significant attention for its anticancer potential, reflecting a critical need in the ongoing battle against cancer. Amidst increasing cancer incidence, the quest for safer and more effective treatments has brought diosmin to the forefront, given its unique pharmacological profile distinct from other flavonoids. Diosmin's anticancer mechanisms are multifaceted, involving apoptosis induction, angiogenesis inhibition, and metastasis prevention. Extensive research encompassing cellular studies, animal models, and limited clinical trials underscores its efficacy not only against cancer but also in managing chronic venous insufficiency and hemorrhoids, attributing to its anti‐inflammatory properties. Furthermore, diosmin exhibits low toxicity and complements conventional chemotherapy, proposing its utility as an adjunct therapy in cancer treatment protocols. The review delves into the specific anticancer advantages of diosmin, distinguishing it from the broader flavonoid category. It provides a detailed analysis of its implications in preclinical and clinical settings, advocating for its consideration in the oncological therapeutic arsenal. By juxtaposing diosmin with other herbal medicines, the review offers a nuanced perspective on its role within the wider context of natural anticancer agents, emphasizing the need for further clinical research to substantiate its efficacy and safety in oncology.

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Phenolic diversity and antioxidant potential of different varieties of bamboo leaves using LC-ESI-QTOF-MS/MS and LC-ESI-QqQ-MS/MS

Andressa Almeida Farias,

Rodrigues dos Reis,

Rodrigues de Morais

et al. 2024

Food Research International

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Identification of active compound combination contributing to anti-inflammatory activity of Xiao-Cheng-Qi Decoction via human intestinal bacterial metabolism

Cited by 4 publications

References 49 publications

Considering traditional Chinese medicine as adjunct therapy in the management of chronic constipation by regulating intestinal flora

Considering traditional Chinese medicine as adjunct therapy in the management of chronic constipation by regulating intestinal flora

Diosmin: A promising phytochemical for functional foods, nutraceuticals and cancer therapy

Phenolic diversity and antioxidant potential of different varieties of bamboo leaves using LC-ESI-QTOF-MS/MS and LC-ESI-QqQ-MS/MS

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