30-year trends in asthma and the trends in relation to hospitalization and mortality

Pelkonen, Margit; Notkola, Irma‐Leena; Laatikainen, Tiina; Jousilahti, Pekka

doi:10.1016/j.rmed.2018.07.012

Cited by 19 publications

(21 citation statements)

References 36 publications

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“…Similarly, 54 320 adult subjects were examined in seven independent crosssectional population surveys repeated every ve years between 1982 and 2012 in Finland. All-cause mortality decreased between 1982 and 2015, though mortality in asthmatic subjects compared with nonasthmatics was higher from all causes 22 . Another study from Finland looked at a smaller number of patients over the age of 30.…”

Section: Discussionmentioning

confidence: 98%

Developments in asthma incidence and prevalence in Alberta between 1995 and 2015

Bosonea

Sharpe

Wang

et al. 2020

Preprint

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Background: Asthma is a chronic respiratory disease characterized by reversible bronchoconstriction and airway inflammation. According to Statistics Canada in 2014, 8.1% of Canadians aged 12 and older reported having asthma diagnosed by a health care professional. Therefore, in 2014 there were an estimated 274,661 persons with asthma in Alberta. Most epidemiological studies estimate prevalence and incidence using survey-based data, which has limitations. The Ontario Asthma Surveillance Information System (OASIS) group has developed and validated an algorithm for epidemiologic asthma studies using provincial health databases. In Alberta, there are some studies using provincial databases, but most are restricted to Emergency Department visits and do not represent the entire asthma population. Using the validated asthma definition for epidemiologic studies, we performed an analysis of the Alberta Health administrative databases to investigate and report province-wide asthma prevalence, incidence and mortality in Alberta from 1995 to 2015. Methods: Data from administrative databases, provided by Alberta Health, was analyzed to determine age and sex specific prevalence, incidence and mortality of the asthma population. The population cohort was all individuals residing in the province of Alberta, ages 0 to 99 from 1995-2015. Kendall’s Tau coefficient test was used to ascertain whether the observed trends were statistically significant. Results: Between 1995 and 2015, the age-standardized incidence of asthma decreased by more than 50% in both males and females. Prevalence; however, increased 3-fold over the 20 years for both genders from 3.9% to 12.3% (Tau=1.00, p<0.0001) in females and from 3.5% to 11.6% (Tau=1.00, p<0.0001) in males. Thus, in 2015 there were 496,927 people with asthma in Alberta. All-cause mortality in the asthma population decreased over time, in both females (Tau=-0.71, p<0.0001) and males (Tau=-0.69, p=0.0001). For the last several years, all-cause mortality was higher in those with asthma. There were ~7 deaths/1000 in the population with asthma versus ~5 deaths/1000 in those without asthma. Conclusions: The incidence of asthma decreased in both females and males while prevalence continued to increase, but at a slower rate than previously. All-cause mortality in asthma patients was higher than in those without asthma, but both decreased over time.

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Section: Discussionmentioning

confidence: 98%

Developments in asthma incidence and prevalence in Alberta between 1995 and 2015

Bosonea

Sharpe

Wang

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…Similarly, 54,320 adult subjects were examined in seven independent cross-sectional population surveys repeated every 5 years between 1982 and 2012 in Finland. All-cause mortality decreased between 1982 and 2015, though mortality in asthmatic subjects compared with non-asthmatics was higher from all causes [22]. Another study from Finland looked at a smaller number of patients over the age of 30.…”

Section: Discussionmentioning

confidence: 99%

Developments in asthma incidence and prevalence in Alberta between 1995 and 2015

Bosonea

Sharpe

Wang

et al. 2020

Allergy Asthma Clin Immunol

View full text Add to dashboard Cite

Background Asthma is a chronic respiratory disease characterized by reversible bronchoconstriction and airway inflammation. According to Statistics Canada in 2014, 8.1% of Canadians aged 12 and older reported having asthma diagnosed by a health care professional. Therefore, in 2014 there were an estimated 274,661 persons with asthma in Alberta. Most epidemiological studies estimate prevalence and incidence using survey-based data, which has limitations. The Ontario Asthma Surveillance Information System (OASIS) group has developed and validated an algorithm for epidemiologic asthma studies using provincial health databases. In Alberta, there are some studies using provincial databases, but most are restricted to emergency department visits and do not represent the entire asthma population. Using the validated asthma definition for epidemiologic studies, we performed an analysis of the Alberta Health administrative databases to investigate and report province-wide asthma prevalence, incidence and mortality in Alberta from 1995 to 2015. Methods Data from administrative databases, provided by Alberta Health, was analyzed to determine age and sex specific prevalence, incidence and mortality of the asthma population. The population cohort was all individuals residing in the province of Alberta, ages 0 to 99 from 1995–2015. Kendall’s Tau coefficient test was used to ascertain whether the observed trends were statistically significant. Results Between 1995 and 2015, the age-standardized incidence of asthma decreased by more than 50% in both males and females. Prevalence, however, increased threefold over the 20 years (for both genders) from 3.9 to 12.3% (Tau = 1.00, p < 0.0001) in females and from 3.5 to 11.6% (Tau = 1.00, p < 0.0001) in males. Thus, in 2015 there were 496,927 people with asthma in Alberta. All-cause mortality in the asthma population decreased over time, in both females (Tau = − 0.71, p < 0.0001) and males (Tau = − 0.69, p = 0.0001). For the last several years, all-cause mortality was higher in those with asthma. There were ~ 7 deaths/1000 in the population with asthma versus ~ 5 deaths/1000 in those without asthma. Conclusions The incidence of asthma decreased in both females and males while prevalence continued to increase, although at a slower rate than previously. All-cause mortality in asthma patients was higher than in those without asthma, but both decreased over time.

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“…Pelkonen et al, 2018, reported that hospitalized asthmatic patients without airway flow limitations did not have higher mortality than those with chronic obstructive pulmonary disease ( p = 0.001) [ 14 ]. The UK National Review of Asthma Deaths (NRAD) studied 900 deaths of people of all ages in 2012 under ICD-10 code J459.…”

Section: Introductionmentioning

confidence: 99%

Asthma Mortality and Hospitalizations in Mexico from 2010 to 2018: Retrospective Epidemiologic Profile

Carrillo

Méndez-Domínguez

Datta-Banik

et al. 2020

IJERPH

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Acute respiratory infections have been established as the principal cause of disease in the Mexican population from 2000 to 2018; however, even when these diseases may aggravate asthma, there is a lack of epidemiologic evidence on the health outcomes when both conditions coexist. Learning about the asthma hospitalizations trends will help us identify monthly variation of hospitalizations, vulnerable groups, needed services, and improvements in therapeutics and prevention. This study aims to analyze the variation in asthma hospitalizations and mortality during the 2010–2018 period in Mexico. Data were obtained from the General Board of Health Information (DGIS) Open Access datasets, which were analyzed taking hospital discharges and hospital deaths recorded from 2010 to 2018 from all public hospitals nationwide. The binomial logistic regression analyses were performed to determine the association between patient ages, hospitalization month, and mortality. The death rate from asthma in Mexico decreased between 2010 and 2018. Still, the hospital mortality rate shows recent improvement; however, prognosis of hospitalized patients depends on their age, accurate diagnosis, length of hospital stay and occurrence of nosocomial infection.

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30-year trends in asthma and the trends in relation to hospitalization and mortality

Abstract: There was an increasing trend in the prevalence of asthma and a declining trend in hospitalization, especially in asthmatic subjects.

Cited by 19 publications

References 36 publications

Developments in asthma incidence and prevalence in Alberta between 1995 and 2015

Developments in asthma incidence and prevalence in Alberta between 1995 and 2015

Developments in asthma incidence and prevalence in Alberta between 1995 and 2015

Asthma Mortality and Hospitalizations in Mexico from 2010 to 2018: Retrospective Epidemiologic Profile

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