3-Year Outcomes of Transcatheter Mitral Valve Repair in Patients With Heart Failure

Transcatheter mitral valve repair and replacement. Expert consensus statement of the Polish Cardiac Society and the Polish Society of Cardiothoracic Surgeons

“…In contrast, the MITRA-FR study included more patients with severe left ventricular dysfunction and a relatively less severe MR as a major cause of HF. Results of the extended 3-year follow-up of patients in the COAPT study confirmed the effectiveness of TMVR with the Mitr-aClip system in reducing mortality and rehospitalization rates and improving the quality of life [8].…”

JCS/JHFS 2021 Guideline Focused Update on Diagnosis and Treatment of Acute and Chronic Heart Failure

“…A recent work of COAPT with extended follow-up through 36 months demonstrated that there was no loss of effectiveness with Mitra-Clip treatment nor did new safety concerns emerge. 131 In addition, compared with patients who continued treatment with GDMT alone, patients assigned to GDMT alone who crossed over and received a MitraClip experienced fewer subsequent heart failure hospitalizations and deaths, with rates comparable with patients originally treated with the MitraClip. Thus, patients meeting COAPT eligibility criteria might benefit from MitraClip reduction of severe mitral regurgitation even after an extended period of GDMT.…”

JCS/JHFS 2021 Guideline Focused Update on Diagnosis and Treatment of Acute and Chronic Heart Failure

“…A recent work of COAPT with extended follow-up through 36 months demonstrated that there was no loss of effectiveness with MitraClip ® treatment nor did new safety concerns emerge. 131 In addition, compared with patients who continued treatment with GDMT alone, patients assigned to GDMT alone who crossed over and received a MitraClip ® experienced fewer subsequent heart failure hospitalizations and deaths, with rates comparable with patients originally treated with the MitraClip ® . Thus, patients meeting COAPT eligibility criteria might benefit from MitraClip ® reduction of severe mitral regurgitation even after an extended period of GDMT.…”