3-[(Furan-2-yl)carbonyl]-1-(pyrimidin-2-yl)thiourea

Singh, Durga P.; Pratap, Seema; Gupta, Sushil K.; Butcher, Ray J.

doi:10.1107/s1600536812044029

Cited by 3 publications

(3 citation statements)

References 11 publications

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“…The asymmetric unit of the structure contains two molecules, which are linked by a pair of intermolecular N-H•••S hydrogen bonds forming an R 2 2 (8) motif. The main bond lengths are within the ranges obtained for similar compounds (Koch 2001;Pérez et al, 2008, Singh et al 2012c. The C6A-S1A [1.667 (2) Å], C6B-S1B [1.665 2 (Allen et al, 1987).…”

Section: S1 Commentsupporting

confidence: 77%

1-(2-Furoyl)-3-(2-methoxy-4-nitrophenyl)thiourea

Pratap¹,

Singh²,

Gupta³

et al. 2013

Acta Cryst E

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The asymmetric unit of the title compound, C13H11N3O5S, contains two independent molecules, which are linked by a pair of intermolecular N—H⋯S hydrogen bonds, forming an R 2 2(8) ring motif. The central thiourea core forms dihedral angles of 3.02 (12) and 14.00 (10)° with the essentially planar furoyl groups [maximum deviations = 0.030 (2) and 0.057 (2) Å] in the two molecules and dihedral angles of 2.43 (13) and 8.03 (12)° with the benzene rings. The dihedral angles between the furoyl and benzene rings in the two molecules are 3.97 (10) and 5.98 (9)°. The trans–cis geometry of the thiourea group is stabilized by three intramolecular N—H⋯O hydrogen bonds involving carbonyl and methoxy O atoms with the H atom of the cis-thioamide group and between furan O atom and the other thioamide H atom. There is also a weak intramolecular C—H⋯S interaction in each molecule.

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Section: S1 Commentsupporting

confidence: 77%

1-(2-Furoyl)-3-(2-methoxy-4-nitrophenyl)thiourea

Pratap¹,

Singh²,

Gupta³

et al. 2013

Acta Cryst E

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“…N-(Pyrimidin-2-ylcarbamothioyl)furan-2-carboxamide ligand (HL) was prepared from furoyl chloride, potassium thiocyanate, and 2-aminopyrimidine in dry acetone. 27 The reaction of the prepared ligand with dimeric ruthenium precursors [RuCl 2 (η 6 -arene)] 2 precursors (η 6 -arene = pcymene or mesitylene) in a 2:1 molar ratio (Scheme 2) resulted in two different types of new arene Ru(II) complexes, viz., [RuCl(HL)(η 6 -p-cymene)]Cl (1) and [RuCl 2 (L)(η 6mesitylene)](2) in 82 and 76% yield, respectively. The ligand behaves as a neutral N,S-chelate in cationic complex 1 and as a monoanionic N,S-chelate in complex 2.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

Non-Pincer-Type Arene Ru(II) Catalysts for the Direct Synthesis of Azines from Alcohols and Hydrazine under Aerobic Conditions

2020

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An efficient tandem synthetic approach to azines from the coupling of alcohols and hydrazine hydrate catalysed by newly synthesized arene Ru(II) complexes has been described. Two arene ruthenium(II) N-(pyrimidin-2-ylcarbamothioyl)furan-2carboxamide complexes have been fully characterised by analytical and spectral methods. The structures of the complexes have been confirmed with the aid of single-crystal X-ray analysis. The unprecedented coordination modes of N-(pyrimidin-2ylcarbamothioyl)furan-2-carboxamide ligand and the formation of four and six membered N,S-chelate complexes have been observed for the first time. Further, the new Ru(II) complexes act as an efficient catalyst for the synthesis of symmetrical azines. A diverse range of azines was synthesized. The products were isolated in good to excellent yields using a catalyst loading of 0.5 mol %. The catalytic reaction operates under aerobic and mild reaction conditions with the release of water as the only by-product. Plausible mechanism has been proposed and it is believed that the reaction proceeds initially via an aldehyde intermediate.

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“…Currently, their corresponding complexes derivatives played a vital role in a wide range of different areas due to the nature of O, N, S atoms, the delocalized electrons and geometrical structure which effect directly in the behaviour of transition element complexes [2]. These compounds represent privilege chelating ligands in coordination chemistry and their transition element complexes are worthwhile and valuable in various fields such as: magnetic materials, constructional component to synthesis a large set heterocyclic compounds, homogenous catalysis, redox sensor, strong selective of metal complexes in liquidliquid extraction system [3][4][5][6][7]. As well as, the existence of sulfur, nitrogen and oxygen atoms in organic compounds and their complexes earn them and enhance the pharmacological and biological activity as antimicrobial, antifungal, antiviral agents and so on [8][9][10][11][12][13][14][15][16][17][18][19].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Studies Of Novel 3,4-Dichloro-N-((5-ChloroPyridin-2-yl)Carbamothioyl)Benzamide Based On Its Complexes With Copper(II), Cobalt(II), Nickel(II) and Zinc(II) ions

2021

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The synthesis of novel N,Nʹ-disubstituted benzoyl thiourea ligand [3,4-dichloro-N-((5-chloropyridin-2-yl)carbamothioyl) benzamide] (L) is achieved in two steps. First step by refluxing KSCN with 3,4-dichloro benzoyl chloride in CH3CN solvent and the other step by the reaction of the resulting filtrate from the first step with 2-amino-5-chloropyridine. The copper(II), Cobalt(II), Nickel(II) and Zinc(II) chloride and acetate salts were coordinated with L ligand in the 1:1 and 1:2 mole ratios (M:L) in the solvent mixture of DMF/H2O or CHCl3/methanol to form the complexes with structural formulas {[LMCl2] and [L2M](CH3COO)2, M= Copper(II), Cobalt(II), Nickel(II) and Zinc(II) ions}. Two mole ratios of the starting materials, 1:1 and 1:2 (M:L) were experimented to form chloride complexes, the product was with structural formula [LMCl2] while acetate complexes with [L2M](CH3COO)2 formula are resulted with the same conditions. Ligand L and its complexes [LCuCl2], [LCoCl2], [LNiCl2], [LZnCl2], [L2Cu](CH3COO)2, [L2Co](CH3COO)2, [L2Ni](CH3COO)2 and [(L)2Zn](CH3COO)2 have been characterized by mass spectrometry, elemental analysis, magnetic moments, conductivity measurements, solubility test, UVvisible, FTIR, 1 H and 13 C NMR spectroscopies. Electrochemical studies were probed by using cyclic voltammetry technique(CV). The data reflect the quasi-reversible reductive nature for the Copper(II) complexes with one electron transfer process while Nickel(II) and Cobalt(II) complexes exhibited two consecutive irreversible reductive nature. The observed UVvisible, elemental analysis, molar conductivity, magnetic moment measurements and solubility test revealed that the metal ion in the all prepared complexes adopted four coordinated square planar structures and [LCuCl2], [LCoCl2], [LNiCl2], [LZnCl2], are formed as neutral complexes while [L2Cu](CH3COO)2, [L2Co](CH3COO)2, [L2Ni](CH3COO)2 and [(L)2Zn](CH3COO)2 adopted anion complexes. The observed magnetic moments show diamagnetic properties of Zinc(II) and Nickel(II) complexes while Copper(II) and Cobalt(II) appeared as paramagnetic species. FT-IR analysis confirmed the coordination sites between the central metal ion with ligand L through two sites, the nitrogen atom in pyridyl ring and the sulphur atom in C=S group.

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3-[(Furan-2-yl)carbonyl]-1-(pyrimidin-2-yl)thiourea

Cited by 3 publications

References 11 publications

1-(2-Furoyl)-3-(2-methoxy-4-nitrophenyl)thiourea

1-(2-Furoyl)-3-(2-methoxy-4-nitrophenyl)thiourea

Non-Pincer-Type Arene Ru(II) Catalysts for the Direct Synthesis of Azines from Alcohols and Hydrazine under Aerobic Conditions

Electrochemical Studies Of Novel 3,4-Dichloro-N-((5-ChloroPyridin-2-yl)Carbamothioyl)Benzamide Based On Its Complexes With Copper(II), Cobalt(II), Nickel(II) and Zinc(II) ions

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