3-D manipulation of millimeter- and micro-sized objects using an acoustically excited oscillating bubble

Chung, Sang Kug; Cho, Sung Kwon

doi:10.1007/s10404-008-0324-2

Cited by 57 publications

(36 citation statements)

References 20 publications

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“…However, recently there has been a growing trend in harnessing this byproduct for a variety of novel applications (Rife et al 2000;Tsai and Lin 2002;Hilgenfeldt 2003, 2004;Dijkink et al 2006;Marmottant et al 2006;Hettiarachchi et al 2007; Kao et al 2007; Tho et al 2007;Xu and Attinger 2007;Chung and Cho 2008;Ahmed et al 2009a, b;Chung and Cho 2009;Tovar and Lee 2009). The first practical use of trapped air bubbles in a microfluidic device utilized acoustic energy to rapidly mix two fluids within a chamber (Liu et al 2002) for the increase of DNA hybridization (Liu et al 2003a, b).…”

Section: Introductionmentioning

confidence: 99%

Lateral air cavities for microfluidic pumping with the use of acoustic energy

Tovar

Patel

Lee

2011

Microfluid Nanofluid

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An acoustically activated micropump is fabricated and demonstrated using a single step lithography process and an off-chip acoustic energy source. Using angled lateral cavities with trapped air bubbles, acoustic energy is used to oscillate the liquid-air interface to create a fluidic driving force. The angled lateral cavity design allows for fluid rectification from the first-order pulsatile flow of the oscillating bubbles. The fluid rectification is achieved through the asymmetrical flow produced by the oscillating interface generating fluid flow away from the lateral cavity interface. Simulation and experimental results are used to develop a pumping mechanism that is capable of driving fluid at pressures of 350 Pa. This pumping system is then integrated into a stand-alone battery operated system to drive fluid from one chip to another.

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Section: Introductionmentioning

confidence: 99%

Lateral air cavities for microfluidic pumping with the use of acoustic energy

Tovar

Patel

Lee

2011

Microfluid Nanofluid

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“…The capturing of microparticles and various objects using oscillating bubbles was intensively studied by Chung et al. 39,[74][75][76] The effects of the frequency and amplitude of acoustic excitation and AC-EWOD actuation on the capturing of microparticles are quantified with the bubble oscillation amplitude using high-speed imaging. 75 Figure 13 shows the effects of frequency on capturing by AC-EWOD actuation.…”

Section: Microstreaming Flow/radiation Forcementioning

confidence: 99%

Bubble actuation by electrowetting-on-dielectric (EWOD) and its applications: A review

Chung

Rhee

Cho

2010

Int. J. Precis. Eng. Manuf.

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This paper reviews the principles, operations, and applications of bubble-based electrowetting-on-dielectric (EWOD). EWOD has proved to be an efficient tool in digital microfluidics that employs discrete droplets, and various applications that use the principles of EWOD have been developed from lab-on-a-chip to optical systems. Similar to its use with droplets, EWOD can also be applied to gaseous bubbles. This review begins with a discussion of the principles of EWOD for a bubble on an electrode covered with a hydrophobic dielectric layer. It then addresses EWOD actuation and the transportation of a bubble in an aqueous medium, along with a physical explanation of bubble motion. The operation of EWOD is then extended to the on-chip creation/elimination and splitting of bubbles. In particular, micro-mixers and pumps are discussed as potential applications of these operations. Unlike droplets, bubbles can be easily oscillated by external excitation, which provides additional functionalities. By integrating EWOD with external excitation, a number of new advanced applications are introduced, including the capture/separation of particles and the propulsion of objects. In these advanced operations, cavitational microstreaming flows and acoustic radiation forces are mainly responsible for the physical mechanisms. This paper also discusses these advanced operations along with their underlying physics. It is expected that in addition to bubble oscillation, other bubble actuation modes will create new functionalities and new potential applications.

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“…Grilli et al [16] developed a dielectrophoretic method for trapping particles. Chung et al [17] generated a stream by oscillating a bubble for 3D manipulation of microobjects. Nieuwstadt et al [18] applied inertial lift force for sorting particles.…”

Section: Introductionmentioning

confidence: 99%

“…Tatsuno et al [21] analyzed circulatory stream in two dimensions around an oscillating circular cylinder in one direction. Lee et al manipulated multiple micro-objects using twin bubbles attached to a rod [22], and Chung et al and Rogers et al focused on manipulating a single object using acoustically oscillating bubbles [17,23,24]. They utilized the stream made by the oscillating bubbles, which can control the position of the objects.…”

Section: Introductionmentioning

confidence: 99%

Analysis of rotational flow generated by circular motion of an end effector for 3D micromanipulation

et al. 2017

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This paper presents a non-contact manipulation method using rotational flow generated by high speed motion of a glass needle. In order to generate an applicable motion that can precisely control the speed and position of a target object around an end effector, a manipulator actuated by three piezoelectric actuators is proposed. A compact parallel link produces precise three-dimensional motions. To reach the required end-effector frequency and amplitude, which is necessary for generating the rotational flow that can make rotational movement of microbeads having patterned data, the end effector motion is generated by controlling the three piezoelectric actuators at high speed. In this paper, we focus on rotational flow created by two-dimensional circular motion of the end effector mounted on the parallel link. By changing the amplitude and frequency of the circular motion, the generated swirl flow is analyzed in 3D space using 9.6-μm microbeads. We analyzed the velocity toward to the root of the end effector and angular velocity around the end effector by formulating models. From the analyzed data, we verified that the rotational flow has potential to manipulate micro-objects precisely in 3D space.

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3-D manipulation of millimeter- and micro-sized objects using an acoustically excited oscillating bubble

Cited by 57 publications

References 20 publications

Lateral air cavities for microfluidic pumping with the use of acoustic energy

Lateral air cavities for microfluidic pumping with the use of acoustic energy

Bubble actuation by electrowetting-on-dielectric (EWOD) and its applications: A review

Analysis of rotational flow generated by circular motion of an end effector for 3D micromanipulation

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