3 : 4-Dimethoxyphenylethylamine, a normal or abnormal metabolite?

Narasimhachari, N.; Plaut, J.; Himwich, Harold E.

doi:10.1016/0022-3956(72)90029-5

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1972

1981

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Cited by 7 publications

(1 citation statement)

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“…the p-O-methylation product of dopamine. Faurbye and Find (1964) and Narasimhachari et al (1972), however, failed to isolate this dimethylated dopamine metabolite from the urine of chronic schizophrenic patients. A considerable controversy arose in the course of which more than 50 papers have appeared, some confirming but many more challenging the association of 'pink spot' with schizophrenia' or its identification as DMPEA.…”

Section: Theoretical Aspectsmentioning

confidence: 99%

Nicotinic Acid in the Treatment of Schizophrenias

Ban¹

1975

Neuropsychobiology

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Section: Theoretical Aspectsmentioning

confidence: 99%

Nicotinic Acid in the Treatment of Schizophrenias

Ban¹

1975

Neuropsychobiology

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Gas-liquid chromatography and mass spectrometry of biologically active primary amines as their isothiocyanate derivatives

Narasimhachari¹,

Vouros

1974

Biol. Mass Spectrom.

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Abstract-Biologically active primary amines (phenethylamines, amphetamines and tryptamines) form thermally stable isothiocyanate derivatives by reacting with carbon disulfide. Phenolic hydroxyl and indole (NH) nitrogens are further converted to their trimethylsilyl derivatives. The gas chromatographic and mass spectrometric properties of several amines are presented. It is shown that the combined use of gas chromatography and mass spectrometry of these derivatives is well suited for the differentiation of several structural isomers. Fragmentation mechanisms leading to the formation of structurally significant ions are discussed.

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On the Development and Utilization of Assays for Biological Transmethylation Involving S-Adenosylmethionine

Baldessarini

1978

Transmethylations and the Central Nervous System

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3 : 4-Dimethoxyphenylethylamine, a normal or abnormal metabolite?

Cited by 7 publications

References 12 publications

Nicotinic Acid in the Treatment of Schizophrenias

Nicotinic Acid in the Treatment of Schizophrenias

Gas-liquid chromatography and mass spectrometry of biologically active primary amines as their isothiocyanate derivatives

On the Development and Utilization of Assays for Biological Transmethylation Involving S-Adenosylmethionine

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