2α, 3β, 19‐Triacetoxy‐14α‐hydroxy‐5α‐card‐20:22‐enolid: Teilsynthese. Zusätzlicher Beweis für die Struktur des Calotropagenins. Glykoside und Aglykone, 324. Mitteilung

Lardon, A.; Stöckel, K.; Reichstein, T.

doi:10.1002/hlca.19700530122

Cited by 13 publications

(1 citation statement)

References 16 publications

(3 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Chromatographic separation of the chloroform and n -butanol fractions of ethanol extract of Cp on silica gel, Sephadex LH-20, and RP-18 silica yielded one new lignan 7′-methoxy-3′- O -demethyl-tanegool-9- O - β - d -glucopyranoside ( 1 ) ( Figure 1 ) and five known compounds, methyl ferulate ( 2 ), rosmarinic acid ( 3 ), methyl rosmarinate ( 4 ) [ 21 ], methyl 4- β - d -glucopyranosyl-ferulate ( 5 ) [ 22 ], and pinoresinol 4- O -glucoside ( 6 ) [ 23 ] from flowers; four known compounds, β -sitosterol ( 7 ), lupeol ( 8 ), lupeol-3- O -acetate ( 9 ) [ 24 ], and calotropagenin ( 10 ) [ 25 ], from leaves; and flavonoid glycoside kaempferol 3- O - α - l -rhamnopyranosyl-(1→6)- β - d -glucopyranoside ( 11 ) and syringaresinol 4- O -glucoside ( 12 ) from the fruits. Their structures were elucidated by spectroscopic data analysis, including IR, 1D and 2D NMR, and HRESIMS.…”

Section: Resultsmentioning

confidence: 99%

Evaluation of Antiulcer and Cytotoxic Potential of the Leaf, Flower, and Fruit Extracts of Calotropis procera and Isolation of a New Lignan Glycoside

Al‐Taweel

Perveen

Fawzy

et al. 2017

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

Calotropis procera is traditionally used for treating many diseases including ulcers and tumors. It was thus deemed of interest to investigate and compare the antiulcer and cytotoxic activities of C. procera leaf, flower, and fruit extracts in an attempt to verify its traditional uses. Phytochemical studies on the fruits, flowers, and leaves of C. procera, collected from the desert of Saudi Arabia, led to the isolation of one new lignan 7′-methoxy-3′-O-demethyl-tanegool-9-O-β-d-glucopyranoside and five known compounds from the flowers, four compounds from leaves, and a flavonoid glycoside and a lignan glycoside from the fruits. The structures of compounds were determined by spectroscopic techniques. Ethanol extracts of the three parts of C. procera were evaluated for their antiulcer activity and we found that the leaf extract possessed a powerful antiulcer activity which could be considered as a promising drug candidate. All the extracts and the isolated compounds were evaluated for their cytotoxic activity against MCF-7, HCT-116, HepG-2, and A-549 human cancer cell lines. Compound 2 was highly active on all the cell lines, whereas compounds 5 and 11 were more selective on colon and liver cell lines. Compound 10 demonstrated a significant activity on liver and lung cancer cell lines.

show abstract

Section: Resultsmentioning

confidence: 99%

Evaluation of Antiulcer and Cytotoxic Potential of the Leaf, Flower, and Fruit Extracts of Calotropis procera and Isolation of a New Lignan Glycoside

Al‐Taweel

Perveen

Fawzy

et al. 2017

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

show abstract

Reductions by Metal Alkoxyaluminum Hydrides. PartII. Carboxylic Acids and Derivatives, Nitrogen Compounds, and Sulfur Compounds

Málek

1988

Organic Reactions

View full text Add to dashboard Cite

In continuation of the previous review on reductions by metal alkoxyaluminum hydrides, this chapter is devoted to reductions of carboxylic acids and their derivatives, open‐chain and heterocyclic nitrogen compounds, and open‐chain and heterocyclic sulfur compounds by alkoxyaluminum hydrides, metal alkoxyaluminum hydrides, and chiral metal alkoxyaluminohydride complexes. Emphasis is placed on the scope, limitations, and the synthetic utility of metal alkoxyaluminum hydrides. Accepted views on reaction mechanisms are mentioned briefly. Discussion of alternative methods of reduction, particularly those using other metal hydrides or complex metal hydrides, is limited to examples of the most important transformations of functional groups; reducing properties of these hydrides and hydride reagents such as borane–dimethyl sulfide, amine boranes, haloboranes, organoboranes, sodium borohydride–pyridine, sodium borohydride–triphenyl borate, sodium borohydride—transition‐metal complexes, potassium triisopropoxyborohydride, and sodium triacyloxyborohydrides have been reported in several papers and reviews. Monographs and reviews summarize reductions with metal alkoxyaluminum hydrides and asymmetric reductions with chiral lithium alkoxyaluminum hydrides and chiral boron reagents.

show abstract

Conformational Analysis by Photoelectron Spectroscopy

Klessinger¹,

Rademacher²

1979

Angew. Chem. Int. Ed. Engl.

View full text Add to dashboard Cite

The conformation of organic molecules may be determined by means of photoelectron (PE) spectroscopy if there are orbital interactions present which depend on a dihedral angle. Straightforward application of the method requires that all ionization bands of interest can be assigned unambiguously and that inductive effects and secondary orbital interactions do not occur or can be accounted for appropriately. In many cases, this method complements conventional methods of conformational analysis. PE conformational analysis is particularly suited to compounds containing vicinal lone pairs or π systems.

show abstract

2α, 3β, 19‐Triacetoxy‐14α‐hydroxy‐5α‐card‐20:22‐enolid: Teilsynthese. Zusätzlicher Beweis für die Struktur des Calotropagenins. Glykoside und Aglykone, 324. Mitteilung

Cited by 13 publications

References 16 publications

Evaluation of Antiulcer and Cytotoxic Potential of the Leaf, Flower, and Fruit Extracts of Calotropis procera and Isolation of a New Lignan Glycoside

Evaluation of Antiulcer and Cytotoxic Potential of the Leaf, Flower, and Fruit Extracts of Calotropis procera and Isolation of a New Lignan Glycoside

Reductions by Metal Alkoxyaluminum Hydrides. PartII. Carboxylic Acids and Derivatives, Nitrogen Compounds, and Sulfur Compounds

Conformational Analysis by Photoelectron Spectroscopy

Contact Info

Product

Resources

About