2D MXenes for combatting COVID-19 Pandemic: A perspective on latest developments and innovations

Panda, Subhasree; Deshmukh, Kalim; Hussain, Chaudhery Mustansar; Pasha, S. K. Khadheer

doi:10.1016/j.flatc.2022.100377

Cited by 17 publications

(11 citation statements)

References 126 publications

(191 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The advantage of MXenes for targeted drug delivery is their hydrophilicity, which increases the bioavailability of drugs for body tissues [ 81 ], high drug loading capacity [ 82 ], as well as facile encapsulation [ 83 ]. This makes MXenes one of the most promising new materials for biomedicine, including various applications for combating COVID-19 [ 84 ].…”

Section: Potential Applications In Medicinementioning

confidence: 99%

Synthesis, Toxicity Assessment, Environmental and Biomedical Applications of MXenes: A Review

et al. 2022

View full text Add to dashboard Cite

MXenes are a family of two-dimensional (2D) composite materials based on transition metal carbides, nitrides and carbonitrides that have been attracting attention since 2011. Combination of electrical and mechanical properties with hydrophilicity makes them promising materials for biomedical applications. This review briefly discusses methods for the synthesis of MXenes, their potential applications in medicine, ranging from sensors and antibacterial agents to targeted drug delivery, cancer photo/chemotherapy, tissue engineering, bioimaging, and environmental applications such as sensors and adsorbents. We focus on in vitro and in vivo toxicity and possible mechanisms. We discuss the toxicity analogies of MXenes and other 2D materials such as graphene, mentioning the greater biocompatibility of MXenes. We identify existing barriers that hinder the formation of objective knowledge about the toxicity of MXenes. The most important of these barriers are the differences in the methods of synthesis of MXenes, their composition and structure, including the level of oxidation, the number of layers and flake size; functionalization, test concentrations, duration of exposure, and individual characteristics of biological test objects Finally, we discuss key areas for further research that need to involve new methods of nanotoxicology, including predictive computational methods. Such studies will bring closer the prospect of widespread industrial production and safe use of MXene-based products.

show abstract

Section: Potential Applications In Medicinementioning

confidence: 99%

Synthesis, Toxicity Assessment, Environmental and Biomedical Applications of MXenes: A Review

et al. 2022

View full text Add to dashboard Cite

show abstract

“…According to the studies reviewed above, certain AgNPs have been utilized to suppress fungi, bacteria, and viruses in vitro and in vivo [ 103 ]. Researchers have employed this nanoscale material to stop COVID-19 [ 104 ]. On the other hand, other studies argue that AgNPs should be used in clinical trials or even in clinical practice for various therapies.…”

Section: Nanoparticles As a Preventive Strategy In Covid-19mentioning

confidence: 99%

Therapeutic and diagnostic applications of nanoparticles in the management of COVID-19: a comprehensive overview

Gholizadeh

Yasamineh

Amini

et al. 2022

Virol J

View full text Add to dashboard Cite

In December 2019, Coronavirus Disease 2019 (COVID-19) was reported in Wuhan, China. Comprehensive strategies for quick identification, prevention, control, and remedy of COVID-19 have been implemented until today. Advances in various nanoparticle-based technologies, including organic and inorganic nanoparticles, have created new perspectives in this field. These materials were extensively used to control COVID-19 because of their specific attribution to preparing antiviral face masks, various safety sensors, etc. In this review, the most current nanoparticle-based technologies, applications, and achievements against the coronavirus were summarized and highlighted. This paper also offers nanoparticle preventive, diagnostic, and treatment options to combat this pandemic. Graphical Abstract

show abstract

“…MXenes are a new group of 2D nanomaterials, synthesized from their MAX phase counterpart by the selective etching of A layers 5 . They have a chemical formula of M n+1 X n T x , where M is an early transition metal, X is carbon and/or nitrogen, T is surface termination groups like F, O, OH, and so forth, x is the number of surface terminations and the value of n varies from 1 to 4 6 . The hydrophilic surface termination groups, metallic conductivity, and high aspect ratio of MXene make it a promising material for energy storage applications 7 .…”

Section: Introductionmentioning

confidence: 99%

“…5 They have a chemical formula of M n +1 X n T x , where M is an early transition metal, X is carbon and/or nitrogen, T is surface termination groups like F, O, OH, and so forth, x is the number of surface terminations and the value of n varies from 1 to 4. 6 The hydrophilic surface termination groups, metallic conductivity, and high aspect ratio of MXene make it a promising material for energy storage applications. 7 The high metallic conductivity of MXene can be utilized for enhancing the dielectric property of the insulating PVA polymer.…”

Section: Introductionmentioning

confidence: 99%

Dielectric, AC conductivity, and complex impedance spectroscopy studies of Ti₂CT_x MXene reinforced polyvinyl alcohol nanocomposites

Panda¹,

Deshmukh

Pasha³

2023

Polymers for Advanced Techs

Self Cite

View full text Add to dashboard Cite

Herein, Ti2CTx MXene‐Polyvinyl alcohol (PVA) nanocomposite films with different weight percent (wt%) of MXene loadings were successfully prepared using the facile solution casting method. The structural, morphological, optical, thermal, and tensile properties of the nanocomposite films were analyzed using FTIR, XRD, Raman, SEM, UV–Vis spectroscopy, TG‐DTA, mechanical tests, and so forth. The variation in dielectric constant, loss tangent, and AC conductivity of the nanocomposite films was analyzed in the range of 1 Hz to 10 MHz with the variation of temperature (30–150°C) and MXene concentrations (5–20 wt%) using impedance spectroscopy. The nanocomposite films showed a very high dielectric constant in the range of ~105 for lower frequency and very low dielectric loss in the range of 0–1 for higher frequency (100 kHz–10 MHz). The dielectric constant, loss tangent, and AC conductivity values increased at a certain temperature and further decreased with increase in temperature. The increase in filler concentration increased the values of these investigated electrical parameters but at a concentration of 20 wt%, the nanocomposite films reached the percolation limit, and hence a slight reduction in the dielectric properties was noticed. Moreover, the complex impedance spectroscopy studies of the nanocomposite films were also carried out and their corresponding circuit diagrams were fitted according to the obtained cole‐cole plots.

show abstract

2D MXenes for combatting COVID-19 Pandemic: A perspective on latest developments and innovations

Cited by 17 publications

References 126 publications

Synthesis, Toxicity Assessment, Environmental and Biomedical Applications of MXenes: A Review

Synthesis, Toxicity Assessment, Environmental and Biomedical Applications of MXenes: A Review

Therapeutic and diagnostic applications of nanoparticles in the management of COVID-19: a comprehensive overview

Dielectric, AC conductivity, and complex impedance spectroscopy studies of Ti₂CT_x MXene reinforced polyvinyl alcohol nanocomposites

Contact Info

Product

Resources

About

2D MXenes for combatting COVID-19 Pandemic: A perspective on latest developments and innovations

Cited by 17 publications

References 126 publications

Synthesis, Toxicity Assessment, Environmental and Biomedical Applications of MXenes: A Review

Synthesis, Toxicity Assessment, Environmental and Biomedical Applications of MXenes: A Review

Therapeutic and diagnostic applications of nanoparticles in the management of COVID-19: a comprehensive overview

Dielectric, AC conductivity, and complex impedance spectroscopy studies of Ti2CTx MXene reinforced polyvinyl alcohol nanocomposites

Contact Info

Product

Resources

About

Dielectric, AC conductivity, and complex impedance spectroscopy studies of Ti₂CT_x MXene reinforced polyvinyl alcohol nanocomposites