2D Detectors for particle physics and for imaging applications

Krüger, H.

doi:10.1016/j.nima.2005.07.037

Cited by 9 publications

(4 citation statements)

References 49 publications

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“…Many (CMOS) pixel imagers were originally developed for high‐energy particle physics applications but are now readily applied to a broader range of imaging applications . Typically, detectors for high‐energy particle physics register individual, charged quanta of radiation with a relatively high spatial and time resolution.…”

Section: Solid‐state Pixel Detectorsmentioning

confidence: 99%

Detection systems for mass spectrometry imaging: A perspective on novel developments with a focus on active pixel detectors

Jungmann

Heeren

2012

Rapid Comm Mass Spectrometry

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Instrumental developments for imaging and individual particle detection for biomolecular mass spectrometry (imaging) and fundamental atomic and molecular physics studies are reviewed. Ion-counting detectors, array detection systems and high mass detectors for mass spectrometry (imaging) are treated. State-of-the-art detection systems for multidimensional ion, electron and photon detection are highlighted. Their application and performance in three different imaging modes -integrated, selected and spectral image detection -are described. Electro-optical and microchannelplate-based systems are contrasted. The analytical capabilities of solid-state pixel detectors -both charge coupled device (CCD) and complementary metal oxide semiconductor (CMOS) chips -are introduced. The Medipix/Timepix detector family is described as an example of a CMOS hybrid active pixel sensor. Alternative imaging methods for particle detection and their potential for future applications are investigated.

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Section: Solid‐state Pixel Detectorsmentioning

confidence: 99%

Detection systems for mass spectrometry imaging: A perspective on novel developments with a focus on active pixel detectors

Jungmann

Heeren

2012

Rapid Comm Mass Spectrometry

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“…Two types of direct electron detection devices are considered in this review: first, a hybrid pixel detector (; Krüger, 2005) and second, a monolithic active pixel sensor (MAPS) based on complementary metal oxide semiconductor (CMOS) technology (Turchetta et al 2001). Both types of detectors have been evaluated for electron microscopy (EM) for a wide range of electron energies and show great potential.…”

Section: Introductionmentioning

confidence: 99%

Electronic detectors for electron microscopy

Faruqi

McMullan

2011

Quart. Rev. Biophys.

104

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Electron microscopy (EM) is an important tool for high-resolution structure determination in applications ranging from condensed matter to biology. Electronic detectors are now used in most applications in EM as they offer convenience and immediate feedback that is not possible with film or image plates. The earliest forms of electronic detector used routinely in transmission electron microscopy (TEM) were charge coupled devices (CCDs) and for many applications these remain perfectly adequate. There are however applications, such as the study of radiation-sensitive biological samples, where film is still used and improved detectors would be of great value. The emphasis in this review is therefore on detectors for use in such applications. Two of the most promising candidates for improved detection are: monolithic active pixel sensors (MAPS) and hybrid pixel detectors (of which Medipix2 was chosen for this study). From the studies described in this review, a back-thinned MAPS detector appears well suited to replace film in for the study of radiation-sensitive samples at 300 keV, while Medipix2 is suited to use at lower energies and especially in situations with very low count rates. The performance of a detector depends on the energy of electrons to be recorded, which in turn is dependent on the application it is being used for; results are described for a wide range of electron energies ranging from 40 to 300 keV. The basic properties of detectors are discussed in terms of their modulation transfer function (MTF) and detective quantum efficiency (DQE) as a function of spatial frequency.

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“…Activity was disappointingly low during the review period in the field of pixellated X-ray detectors. Kruger 28 presented a comprehensive review of two-dimensional X-ray detectors in which he identified the trends to further improve sensor-toelectronics interconnects and signal processing systems and also the way in which detectors for particle physics and medical imaging were already diverging. A straightforward optical CCD coupled to an inexpensive plastic scintillating fibre array was reported by Naseri et al 29 for use in X-ray imaging while Tate and colleagues 30 used simple, commercially available components in a similar arrangement comprising a 1024 by 1024 pixel CCD camera optically coupled to an X-ray sensitive phosphor screen with a standard 35 mm camera lens.…”

Section: Detectorsmentioning

confidence: 99%