Age- and sex-related difference of lipid profile in patients with ischemic stroke in China

Zhao, Pingsen; Liu, Sudong; Zhong, Zhixiong; Liu, Jing

doi:10.1097/md.0000000000010930

Cited by 19 publications

(18 citation statements)

References 31 publications

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“…Our results showed that, there was no significant difference in lipid profile variable between two age groups (younger and older adult). Our results are incontinent with Manjareeka et al [11] and Zhao et al [33]. The contradiction in our findings with other studies is probably due to:(1) the small sample size compared to other studies, (2) most of the subjects who participated in this study, were nearly 40 years old (men40±7, women39±5).…”

Section: Discussioncontrasting

confidence: 91%

“…On the other hand, our results showed that, there was a significant difference in anthropometric indices between two age groups (younger and older adults). Our results are supported by Manjareeka et al [11] and Zhao et al [33]. The difference in anthropometric indices between two age groups is probably due to the fat mass increment related to aging.…”

Section: Discussionsupporting

confidence: 90%

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The Relationship between Anthropometric Indices and Lipid Profiles In-OfficeEmployees

Kushkestani¹,

Parvani²,

Nosrani³

et al. 2020

JSS

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Purpose:The purpose of this study was to investigate the relationship between anthropometric indices and lipid profile in-office employees.Methods: This descriptive study was performed in Tehran, Iran. In total 294 office employees (166 males and 83 females) participated as samples study in this research. Blood samples (TC, TG, HDL-C, LDL-C and LDL-C to HDL-C ratio) were taken from the brachial vein in sitting position and fasting state. Then anthropometric indices includingbody mass index (BMI), waist circumferences (WC) and waist-hip ratio (WHR) were measured and recorded. All statistical analyses were conducted with "SPSS 21". Results: There was a positive and significant correlation between TG and LDL-C/HDL-C ratio with BMI, WC and WHR. There was also a direct and significant correlation between WHR and LDL-C. On the other hand, there was an inverse correlation between HDL with BMI, WC and WHR. Moreover, anthropometric indices (BMI, WC and WHR) were significantly higher in the older group than the younger group. Also, triglycerides, LDL-C and also, BMI, WC and WHR were significantly higher in men than women; but, HDL-C was significantly higher in women. Conclusion: Regarding the association of anthropometric indices with lipid profile and its significant differences across age and gender groups, these parameters can be used to evaluate and screen cardiovascular and metabolic disease-related risk factors.

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Section: Discussioncontrasting

confidence: 91%

Section: Discussionsupporting

confidence: 90%

The Relationship between Anthropometric Indices and Lipid Profiles In-OfficeEmployees

Kushkestani¹,

Parvani²,

Nosrani³

et al. 2020

JSS

View full text Add to dashboard Cite

show abstract

“…Similar to study by Zhao et al, (2018) in which lipid abnormality was more prevalent in nonelderly patients (74% vs. 67%, P<0.05). 9 The proportion of double-abnormality in nonelderly patients was significantly higher than that in elderly patients (27% vs. 21%, P<0.05), whereas no difference was seen. The copper levels were higher in controls, showing imbalance in their levels.…”

Section: Resultsmentioning

confidence: 77%

Role of serum copper and lipid profile in cardiovascular diseases patients of Southern Rajasthan

Dhanak

Sharma

2019

Int J Res Med Sci

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Background: It is clear that deficiencies of some trace elements cause marked alterations in lipid and lipoprotein metabolism. The mechanisms of their effects are not completely obvious and inspite of intense research, the role of these microelements need further elucidation. Thus, the objective of this study is to evaluate the correlations of serum concentrations of trace elements including copper with lipid profile parameters of adult men in Southern Rajasthan.Methods: Present study was conducted in Cardiology and Biochemistry Department in GMCH, Udaipur during the year 2019. A total of 150 MI cases/controls were selected. Blood sample was collected by vein puncture using an aseptic technique. The blood was allowed to settle at 37ºC and then centrifuged at 3000 rpm for 15 min. Serum was then separated and stored at -20ºC until analysis.Results: The study cases had significantly higher lipid values than those of controls (p<0.001). In cases the copper levels are higher than the controls. Copper levels were more in males 95.40±18.93 than in females 86.93±14.54 (p<0.05). Lipid levels were higher in urban population related to rural, TC (238.47 V/s 266.59), TG (219.83 V/s 202.40), HDL (64.39 V/s 54.19) and LDL (131.28 V/s 139.48) (p<0.05). Significant negative correlation was seen in study group between serum copper levels and TC (r=-0.288, p<0.05), TG (r =-0.236, p<0.05), HDL (r=-0.946, p<0.05) and VLDL levels (r=0.102, p<0.05). This indicates that as copper level reduces lipids increases.Conclusions:Our findings indicate the possible effect of Cu level in serum lipid profile and this effect may be due to the role of Cu as an antioxidant. The correlations between the serum concentrations of trace elements with lipid profile in physiological concentrations may not be the same as the changes observed during deficiencies of the trace elements as in hyperlipidemic patients

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“…Similar to the study that of Zhao et al, in which lipid abnormality was more prevalent in nonelderly patients (74% vs. 67%, P<0.05). 12 The proportion of double-abnormality in nonelderly patients was significantly higher than that in elderly patients (27% vs. 21%, P<0.05), whereas no difference was seen. When vitamin C levels were compared between males and females, males had non-significant difference than females (Table 3).…”

Section: Discussionmentioning

confidence: 77%

Role of serum Vitamin-C and lipid profile in cardiovascular diseases patients of Southern Rajasthan

Dhanak

Sharma

2019

Int J Res Med Sci

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Background: Vitamin C's functions as an antioxidant and as an enzyme cofactor are well established, but the ways in which these functions may modify chronic disease risk are less well established. The belief that vitamin C may benefit heart health has stemmed from multiple pieces of evidence and lines of reasoning. Thus, we took the objective of this study to evaluate the correlations of serum concentrations of trace elements including vitamin-C with lipid profile parameters of adult men in Southern Rajasthan.Methods: Present study was conducted in Cardiology and Biochemistry Department in GMCH, Udaipur during the year 2019. A total of 150 MI cases/controls were selected. Blood sample was collected by vein puncture using an aseptic technique. The blood was allowed to settle at 37ºC and then centrifuged at 3000 rpm for 15 min. Serum was then separated and stored at -20ºC until analysis. Vitamin C by NATELSON method on colorimeter.Results: The study cases had significantly higher lipid values than those of controls (p<0.001). In cases the vitamin-C levels were significantly low than the controls. There was significant difference in lipid levels among smokers and nonsmokers. When vitamin C levels were compared there was no statistically significant difference in their levels. There was no significant correlation between serum vitamin C levels and Lipids.Conclusions: The physical characteristics such as diet, residence, smokers, non-smokers, showed significant difference in the controls and cases. Women seemed to have higher proportion of lipid abnormality than men. It is concluded from this study that lower levels of ascorbic acid definitely increase the risk of cardiovascular disease and inclusion of ascorbic acid in the normal diet will control the level of lipids.

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Age- and sex-related difference of lipid profile in patients with ischemic stroke in China

Cited by 19 publications

References 31 publications

The Relationship between Anthropometric Indices and Lipid Profiles In-OfficeEmployees

The Relationship between Anthropometric Indices and Lipid Profiles In-OfficeEmployees

Role of serum copper and lipid profile in cardiovascular diseases patients of Southern Rajasthan

Role of serum Vitamin-C and lipid profile in cardiovascular diseases patients of Southern Rajasthan

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