The effects of medication adherence and health literacy on health‐related quality of life in older people with hypertension

Park, Nam Hee; Song, Mi Sook; Shin, So Young; Jihye, Jeong; Lee, Hyo Young

doi:10.1111/opn.12196

Cited by 57 publications

(65 citation statements)

References 32 publications

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“…The included studies focussed on a wide range of disease areas including pulmonary diseases, osteoporosis, depression, cardiovascular diseases, Parkinson's disease, epilepsy, chronic kidney disease, cancer and diabetes mellitus . Two studies did not measure disease‐specific medication (non‐)adherence .…”

Section: Resultsmentioning

confidence: 99%

“…Two studies did not measure disease‐specific medication (non‐)adherence . Thirty‐six studies were specific to, or provided age stratified analysis for people aged ≥64 years, while the other 30 studies also included middle aged adults (≥50 years) . Thirteen authors of the included texts were contacted via e‐mail for further information, and 8 replied.…”

Section: Resultsmentioning

confidence: 99%

“…Thirteen authors of the included texts were contacted via e‐mail for further information, and 8 replied. In terms of adherence measurement, 54 studies measured medication (non‐)adherence using pharmacy claims data while 11 studies used self‐report methods, consisting of the 4‐item or 8‐item Morisky Medication Adherence Scale, or self‐reported PDC and MEMs was used in 4 studies …”

Section: Resultsmentioning

confidence: 99%

“…Overall, 48 studies were determined to be high quality, 17 were determined to be medium quality and 1 study was deemed to be low quality (Table S8). There was considerable variability with regards to external validity (generalisability), with 15 studies deemed medium quality and 11 studies achieving low quality . This was due to lack of detail on sampling or recruitment procedures or inclusion of specific populations only.…”

Section: Resultsmentioning

confidence: 99%

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The association between medication non‐adherence and adverse health outcomes in ageing populations: A systematic review and meta‐analysis

Walsh

Cahir

Tecklenborg

et al. 2019

Brit J Clinical Pharma

137

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Aims The aim of this systematic review and meta‐analysis was to synthesise the evidence relating to medication non‐adherence and its association with health outcomes in people aged ≥50 years. Methods Seven databases were searched up to February 2019 for observational studies that measured medication (non‐)adherence as a predictor of the following health outcomes in adults aged ≥50 years: healthcare utilisation (hospitalisation, emergency department visits, outpatient visits and general practitioner visits), mortality, adverse clinical events and quality of life. Screening and quality assessment using validated criteria were completed by 2 reviewers independently. Random effects models were used to generate pooled estimates of association using adjusted study results. The full methodological approach was published on PROSPERO (ID: CRD42017077264). Results Sixty‐six studies were identified for qualitative synthesis, with 11 of these studies eligible for meta‐analyses. A meta‐analysis including 3 studies measuring medication non‐adherence in adults aged ≥55 years showed a significant association with all‐cause hospitalisation (adjusted odds ratio 1.17, 95% confidence interval [CI] 1.12, 1.21). A meta‐analysis including 2 studies showed that medication non‐adherence was not significantly associated with an emergency department visit (adjusted odds ratio 1.05, 95% CI 0.90, 1.22). Good adherence was associated with a 21% reduction in long‐term mortality risk in comparison to medication non‐adherence (adjusted hazard ratio 0.79, 95% CI 0.63, 0.98). Conclusion Medication non‐adherence may be significantly associated with all‐cause hospitalisation and mortality in older people. Medication adherence should be monitored and addressed in this cohort to minimise hospitalisation, improve clinical outcomes and reduce healthcare costs.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

The association between medication non‐adherence and adverse health outcomes in ageing populations: A systematic review and meta‐analysis

Walsh

Cahir

Tecklenborg

et al. 2019

Brit J Clinical Pharma

137

View full text Add to dashboard Cite

show abstract

“…Also, the presence of depression and chronic heart disease are associated to lower drug adherence [30]. Therapeutic adherence is higher in patients with better education and better knowledge about their disease, and also with greater economic income [31][32][33]. Adherents present better quality of life, both in their physical and their mental status [34].…”

Section: Resultsmentioning

confidence: 99%

Hypertension: Drug Adherence and Social Factors

de¹,

Paulo²

2018

J Hypertens Manag

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Hypertension literacy: Concept analysis

2023

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AimAnalysis of the concept of hypertension literacy to ensure clarity, reduce ambiguities and promote consistency in usage.DesignWalker and Avant's concept analysis method was adopted.MethodsSearched four electronic databases using keywords combined with the appropriate Boolean operators. After removing duplicates, thirty titles were identified, and ten articles met the basic criteria for inclusion. The analysis was done using a convergent synthesis design to integrate results and transform them into qualitative descriptions.ResultsHypertension literacy's defining attributes were hypertension information search skills, comprehension of numeracy associated with blood pressure and medication and utilization of hypertension prevention information. The identified antecedents were formal education and improved cognitive, social, economic and health‐related experiences. Consequences of hypertension literacy included improved self‐reported and increased health awareness. Hypertension literacy allows nurses to assess and accurately improve knowledge and facilitate people to adopt prevention behaviours.

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The effects of medication adherence and health literacy on health‐related quality of life in older people with hypertension

Abstract: To effectively promote health-related quality of life in vulnerable older people, medication adherence and health literacy of patients should be assessed, and patient-centred intervention strategies that consider their individual differences should be developed.

Cited by 57 publications

References 32 publications

The association between medication non‐adherence and adverse health outcomes in ageing populations: A systematic review and meta‐analysis

The association between medication non‐adherence and adverse health outcomes in ageing populations: A systematic review and meta‐analysis

Hypertension: Drug Adherence and Social Factors

Hypertension literacy: Concept analysis

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