Estimating prevalence and diagnostic test characteristics of bovine cysticercosis in Belgium in the absence of a ‘gold standard’ reference test using a Bayesian approach

Jansen, Famke; Dorny, Pierre; Gabriël, Sarah; Eichenberger, Ramon M.; Berkvens, Dirk

doi:10.1016/j.vetpar.2018.03.013

Cited by 8 publications

(10 citation statements)

References 31 publications

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“…While Ogunremi and Benjamin [11] estimated the sensitivity and specificity of their antibody detecting ELISA (based on excretory secretory antigen) at 92.9% and 90.6%, respectively, this could not be confirmed in a later study, where a sensitivity of 13.8% and a specificity of 92.9% was estimated in animals with low levels of infection [8]. The genus-specific antigen detection ELISA has a high sensitivity (98.7%) for cattle infected with more than 50 viable cysticerci, but the sensitivity reduces significantly when less than 50 cysticerci are present (12.8%) [8,9]. For the detection of human taeniosis cases, the routinely used coprological techniques are also known to have low sensitivities [12] and lack species-specificity.…”

Section: Introductionmentioning

confidence: 81%

“…As an alternative, immuno-diagnostic tools such as enzyme-linked immunosorbent assays (ELISAs) detecting either specific antibodies or circulating antigens have been developed for BCC [10,11]. While Ogunremi and Benjamin [11] estimated the sensitivity and specificity of their antibody detecting ELISA (based on excretory secretory antigen) at 92.9% and 90.6%, respectively, this could not be confirmed in a later study, where a sensitivity of 13.8% and a specificity of 92.9% was estimated in animals with low levels of infection [8]. The genus-specific antigen detection ELISA has a high sensitivity (98.7%) for cattle infected with more than 50 viable cysticerci, but the sensitivity reduces significantly when less than 50 cysticerci are present (12.8%) [8,9].…”

Section: Introductionmentioning

confidence: 99%

“…Diagnosis and control of BCC is primarily based on meat inspection, which involves inspection for cystic lesions using palpation and incision of defined muscles, although the adopted inspection techniques and the final judgments vary greatly throughout the world [3]. Routine meat inspection generally has a low sensitivity (< 15%), especially so for low levels of infection as estimated recently in Belgium (0.76%) [8,9]. As an alternative, immuno-diagnostic tools such as enzyme-linked immunosorbent assays (ELISAs) detecting either specific antibodies or circulating antigens have been developed for BCC [10,11].…”

Section: Introductionmentioning

confidence: 99%

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Identification of risk areas and practices for Taenia saginata taeniosis/cysticercosis in Ethiopia: a systematic review and meta-analysis

et al. 2020

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Background: Bovine cysticercosis (BCC) is an infection of cattle with the metacestode stage of Taenia saginata, the beef tapeworm, which causes taeniosis in humans. BCC is responsible for considerable economic losses in the meat sector worldwide. This systematic review and meta-analysis summarizes the prevalence, risk factors and treatment efforts made so far on T. saginata infections in Ethiopia, providing a detailed analysis of different factors influencing the varying prevalence estimates in Ethiopia to gain more insight into the occurrence and risk factors of T. saginata taeniosis and cysticercosis to date. Methods: A systematic review and meta-analysis was conducted on data collected from published and grey literature accessed through an electronic database and manual search. Results: The literature search resulted in 776 outputs of which 132 conformed to the predefined criteria. The average zonal prevalence of meat inspection-based BCC ranged from 2% in Buno-Bedele to 24.6% in Sidama zone. The pooled prevalence of BCC was influenced by the number of muscle/organs inspected, ranging from 3.4% (95% CI: 1.7-5.1%) using fewer predilection sites to 19.4% (95% CI: 13.3-25.4%) using inspection of a maximum number of predilection sites. None of the tested variables were significantly associated with BCC. Questionnaire-based taeniosis ranged between 19.0% in Halaba special woreda to 70.0% in Gedeo zone and stool test-based taeniosis varied from 0.6% in central Tigray to 10.7% in Gurage zone. Questionnaire-based prevalence of taeniosis was higher in people with a frequent raw beef consumption habit (pooled OR, pOR: 10.5, 95% CI: 6.0-17.9), adults (pOR: 2.5, 95% CI: 1.7-3.6), men (pOR: 2.8, 95% CI: 2.1-3.6), and Christians (pOR: 2.0, 95% CI: 1.4-2.8) compared to less frequent raw beef consumers, younger people, women and Muslims, respectively. Conclusions: This review revealed a widespread but variable occurrence of BCC and taeniosis in Ethiopian regions and zones, urging for harmonized and enhanced detection for improved control of the parasite. Accurate prevalence estimates using more sensitive tests, detailed risk factor analysis, as well as data on financial losses are needed to develop effective control strategies for the Ethiopian epidemiologic condition.

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Section: Introductionmentioning

confidence: 81%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Identification of risk areas and practices for Taenia saginata taeniosis/cysticercosis in Ethiopia: a systematic review and meta-analysis

et al. 2020

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“…However, meat inspection is notorious for its low sensitivity, mainly in carcasses with light infections [87][88][89] which are common in Brazil [7]. According to some studies, the sensitivity of meat inspection ranged from 0.54% [12] up to 2.87% in an enhanced meat inspection system [90] in other countries. The post-mortem inspection for BCC is performed through visual inspection and multiple incisions in muscles (masseters, pterygoids, tongue and heart).…”

Section: How To Control Taenia Saginata In Brazil?mentioning

confidence: 99%

“…The use of serological analyses, such as Ag-ELISA, to detect infected animals also has been suggested but might not be feasible during slaughter [12]. However, serological analyses have been largely carried out, including in Brazil [65][66][67][68] and its use to detect infected animals has improved worldwide [90,95,96], allowing to perform well-designed epidemiological studies.…”

Section: How To Control Taenia Saginata In Brazil?mentioning

confidence: 99%

Systematic review and meta-analysis of bovine cysticercosis in Brazil: current knowledge and way forward

2020

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Background: Taenia saginata taeniosis/cysticercosis has been well studied in several countries. Brazil is one of the most important beef exporting countries and has one of the highest cattle population size in the world. In this country, bovine cysticercosis (BCC) remains the most frequent reported zoonosis detected during post-mortem inspection, resulting in costs for the beef sector and public health. We performed a systematic literature review regarding data about BCC epidemiology in Brazil and meta-analyses for its prevalence in different administrative regions and the distribution over time, and based on this discussed possible control strategies. Methods:A systematic review was conducted to obtain data about BCC in Brazil using the words "bovine cysticercosis" and "Brazil" to construct the search phrase. The inclusion criteria used to select articles were: (i) published from 2000 to 2018; (ii) full text available online in Portuguese or English; and (iii) contain information at least regarding one of the following aspects of BCC in Brazil: prevalence, incidence, spatial distribution, risk-factors, economic burden and measures for control. Results:A set of 42 articles was included, covering the prevalence of BCC in Brazil, ranging between 0.01-18.75%. Prevalence results of 40 articles were included in a meta-analysis per administrative region. The highest prevalence was found in the South (3.4%; 95% CI: 2.0-5.2%), followed by the Southeast (2.7%; 95% CI: 1.9-3.6%), Northeast (1.5%; 95% CI: 0.6-2.7%), Central-western (0.9%; 95% CI: 0.3-1.7%) and North (0.0%; 95% CI: 0.0-0.6%) region. In addition, a reduction in prevalence over time was observed in all the evaluated states except for Alagoas and Pará. Conclusions:Besides the large availability of data, a critical lack of information about BCC epidemiology remains in Brazil. Nevertheless, the available data on prevalence, high risk-areas and risk factors should contribute to a better understanding of transmission and the formulation of recommendations for control. A One Health approach will be required to reduce T. saginata taeniosis/cysticercosis prevalence and the consequent economic burden for the beef sector in Brazil, one of the most important beef exporters in the world.

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Taeniasis and Cysticercosis

Ferrer

Perteguer

2022

Helminth Infections and Their Impact on Global Public Health

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Estimating prevalence and diagnostic test characteristics of bovine cysticercosis in Belgium in the absence of a ‘gold standard’ reference test using a Bayesian approach

Cited by 8 publications

References 31 publications

Identification of risk areas and practices for Taenia saginata taeniosis/cysticercosis in Ethiopia: a systematic review and meta-analysis

Identification of risk areas and practices for Taenia saginata taeniosis/cysticercosis in Ethiopia: a systematic review and meta-analysis

Systematic review and meta-analysis of bovine cysticercosis in Brazil: current knowledge and way forward

Taeniasis and Cysticercosis

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