The absolute bioavailability and the effect of food on a new magnesium lactate dihydrate extended-release caplet in healthy subjects

Dogterom, Peter; Fu, ChauHwei H J; Legg, Thomas J.; Chiou, Yi-Jin; Brandon, Steve

doi:10.1080/03639045.2018.1464020

Cited by 5 publications

(2 citation statements)

References 14 publications

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“…In our study, we selected magnesium sulfate (MgSO4) as the Mg 2+ source since it is less expensive and readily available. Moreover, MgSO4 is also highly soluble (Dogterom et al, 2018). In our study, the concentration of MgSO4 that was added was 200 mg/l.…”

Section: Inoculum Feedstock and Chemicalsmentioning

confidence: 89%

The Effect of Magnesium Sulfate Addition on Volatile Solid Destruction and Chemical Oxygen Demand Reduction of Food Waste Anaerobic Digestion

Hapsari

Tharifa

Moersidik³

et al. 2019

IJTech

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Process instability often occurs in anaerobic digestion (AD) due to inhibitors, such as the high sodium content in food waste. Recent studies have reported that magnesium can reduce the sodium ion's toxicity towards methanogens. This study aimed to analyze the effect of magnesium addition to Volatile Solids Destruction (VSD), Chemical Oxygen Demand (COD) reduction, and biogas production in AD of food waste. The experiment consisted of two phases, the control phase and the experimental phase, without and with MgSO4, respectively. The control phase results were: average COD reduction, VSD, and methane yield up to 80.9%, 87.6%, 340 mL CH4/gr VS/day, respectively. The experimental phase results were: average COD reduction, VSD, and methane yield up to 78.5%, 83.9%, 125 mL CH4/gr VS/day, respectively. Overall, the study's results showed that MgSO4 had a negative impact on VSD and methane yield. The addition of MgSO4 seemed to cause instability in the AD system, which resulted in a decrease in the VSD value and a decrease in the methane concentration.

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Section: Inoculum Feedstock and Chemicalsmentioning

confidence: 89%

The Effect of Magnesium Sulfate Addition on Volatile Solid Destruction and Chemical Oxygen Demand Reduction of Food Waste Anaerobic Digestion

Hapsari

Tharifa

Moersidik³

et al. 2019

IJTech

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“…Magnesium sulfat anhidrat juga dapat larut pada air bersuhu 20 °C sebesar 25,5 gr/100 ml H2O. Sedangkan magnesium sulfat heptahidrat memiliki kelarutan sebesar 71 gr/100 ml H2O pada suhu 20 °C (114)(115)(116)(117)(118) .Magnesium sulfat memiliki nilai konduktivitas (43; 68-71) . Besarnya konduktivitas ditentukan oleh konsentrasi elektrolit.…”

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Analisis Termodinamika Molekul Magnesium Sulphate (MgSO4)

Yuliani¹,

Zainul²

2018

Preprint

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Magnesium sulfat merupakan salah satu garam anorganik dengan rumus kimia MgSO4. Magnesium sulfat ini termasuk senyawa ionik karena terdapat ikatan antara logam magnesium dengan spesi non logam sulfat. Magnesium sulfat bersifat polar, bentuk anhidratnya sangat higroskopik dan mudah memiliki koordinasi dengan air. Umumnya magnesium sulfat terbentuk dalam formasi hidrat MgSO4.xH2O. Penelitian ini bertujuan untuk menganalisis pengaruh sifat termodinamika molekul MgSO4 terhadap interaksi molekuler di dalam senyawa tersebut. Metode yang digunakan ialah pemodelan dengan aplikasi ChemOffice 15.0. Sedangkan untuk data mobilitas ion, konduktivitas, viskositas, kecepatan hanyut dengan menggunakan perhitungan dan data dari hasil review beberapa jurnal penelitian yang berkaitan dengan magnesium sulfat sesuai tahapan yang tertera pada fishbond. Magnesium sulfat memiliki sifat termokimia dalam fasa solid dengan ∆𝐻𝑓,∆𝐺𝑓,𝑆°, 𝑑𝑎𝑛 𝐶𝑝 pada tekanan 1 atm dan suhu 25°C yang masing-masing mempunyai nilai -1284,9 kJ/mol, -1170,7 kJ/mol, 91,6 J/molK dan 96,48 J/molK. Mobilitas ion Mg2+dan SO42- adalah 5,50.10-8m2s-1V-1 dan 8,29.108m2s-1V-1. Panas reaksi standar (ΔHr°) MgSO4 bernilai negatif maka reaksi bersifat eksotermis

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Magnesium

Dharmarajan

Gunturu

2021

Geriatric Gastroenterology

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The absolute bioavailability and the effect of food on a new magnesium lactate dihydrate extended-release caplet in healthy subjects

Abstract: This new magnesium formulation has reasonable bioavailability and might be a valuable addition to the currently available magnesium oral products.

Cited by 5 publications

References 14 publications

The Effect of Magnesium Sulfate Addition on Volatile Solid Destruction and Chemical Oxygen Demand Reduction of Food Waste Anaerobic Digestion

The Effect of Magnesium Sulfate Addition on Volatile Solid Destruction and Chemical Oxygen Demand Reduction of Food Waste Anaerobic Digestion

Analisis Termodinamika Molekul Magnesium Sulphate (MgSO4)

Magnesium

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