Early definitive treatment of partial-thickness alkali burns with tangential excision and biobrane

Kok, Yee Onn; Chong, Si Jack; Basuki, Adi; Tan, Bien Keem

doi:10.5999/aps.2017.00507

Cited by 5 publications

(2 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In full-thickness wounds, Biobrane should be removed from the wound prior to the skin graft. It can be used to cover burns with incomplete skin thickness, skin donor sites or in skin defects caused by diseases such as epidermolysis bullosa [114]. However, there are some side effects of Biobrane such as an increased risk of infection.…”

Section: Class Iii-complex Skin Substitutes (Dermal-epidermal)mentioning

confidence: 99%

Bioengineering Skin Substitutes for Wound Management—Perspectives and Challenges

Kondej,

Zawrzykraj,

Czerwiec

et al. 2024

IJMS

View full text Add to dashboard Cite

Non-healing wounds and skin losses constitute significant challenges for modern medicine and pharmacology. Conventional methods of wound treatment are effective in basic healthcare; however, they are insufficient in managing chronic wound and large skin defects, so novel, alternative methods of therapy are sought. Among the potentially innovative procedures, the use of skin substitutes may be a promising therapeutic method. Skin substitutes are a heterogeneous group of materials that are used to heal and close wounds and temporarily or permanently fulfill the functions of the skin. Classification can be based on the structure or type (biological and synthetic). Simple constructs (class I) have been widely researched over the years, and can be used in burns and ulcers. More complex substitutes (class II and III) are still studied, but these may be utilized in patients with deep skin defects. In addition, 3D bioprinting is a rapidly developing method used to create advanced skin constructs and their appendages. The aforementioned therapies represent an opportunity for treating patients with diabetic foot ulcers or deep skin burns. Despite these significant developments, further clinical trials are needed to allow the use skin substitutes in the personalized treatment of chronic wounds.

show abstract

Section: Class Iii-complex Skin Substitutes (Dermal-epidermal)mentioning

confidence: 99%

Bioengineering Skin Substitutes for Wound Management—Perspectives and Challenges

Kondej,

Zawrzykraj,

Czerwiec

et al. 2024

IJMS

View full text Add to dashboard Cite

show abstract

“…Biobrane TM has also been deployed for temporary coverage of excised deep dermal and full-thickness thermal burns to prepare the wound for autografting, 7 and has reportedly been used for definitive coverage of partial-thickness alkaline burns with good results. 8 The use of Biobrane TM for immediate definitive coverage of thermal burn wounds that have been tangentially excised has not been described in the literature. We reported our experience using this method on four patients with partial-thickness thermal burns.…”

Section: Introductionmentioning

confidence: 99%

Early Experience with Biobranetm for Definitive Coverage of Tangentially Excised Partial-Thickness Thermal Burns

See

Yang

et al. 2021

wjps

Self Cite

View full text Add to dashboard Cite

Biobrane TM is a popular biosynthetic semi-permeable skin substitute conventionally applied onto non-excised partial thickness burn wounds to facilitate healing. The use of Biobrane TM for definitive coverage after excision of partial-thickness thermal burns has not been reported. We highlighted our experience of immediate Biobrane TM application for definitive coverage of tangentially-excised partial thickness thermal burn wounds in four patients. This technique is safe and efficient, minimizes painful and costly dressing changes, avoids the complications associated with autologous skin grafting, and eliminates the unpredictability of burns wound conversion. We believe this method expands the indications for Biobrane TM usage, accelerates wound healing, and provides better aesthetic outcomes.

show abstract

Molecular immunological mechanisms of impaired wound healing in diabetic foot ulcers (DFU), current therapeutic strategies and future directions

Mohsin,

Javaid,

Tariq

et al. 2024

International Immunopharmacology

View full text Add to dashboard Cite

Early definitive treatment of partial-thickness alkali burns with tangential excision and biobrane

Cited by 5 publications

References 4 publications

Bioengineering Skin Substitutes for Wound Management—Perspectives and Challenges

Bioengineering Skin Substitutes for Wound Management—Perspectives and Challenges

Early Experience with Biobranetm for Definitive Coverage of Tangentially Excised Partial-Thickness Thermal Burns

Molecular immunological mechanisms of impaired wound healing in diabetic foot ulcers (DFU), current therapeutic strategies and future directions

Contact Info

Product

Resources

About