Acceptability of intranasal live attenuated influenza vaccine, influenza knowledge and vaccine intent in The Gambia

Armitage, Edwin P.; Camara, Janko; Bah, Sulayman; Forster, Alice S.; Clarke, Ed; Kampmann, Beate; Silva, Thushan I. de

doi:10.1016/j.vaccine.2018.02.037

Cited by 16 publications

(18 citation statements)

References 42 publications

(47 reference statements)

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“…A variety of theoretical frameworks were used to inform the design of the questionnaires used in the studies. The most common was the Health Belief Model (HBM), which was explicitly stated as having been used to inform the questions in 25 (19.0%) studies [ 30 , 32 , 34 – 57 ], followed by the Theory of Planned Behaviour, which was used in 5 (4.3%) studies [ 58 – 63 ]. Other studies that were adapted from existing questionnaires may have implicitly been based on these or other theoretical frameworks as a consequence of having adapted from other questionnaires but did not explicitly claim the theoretical framework as a basis for their questions.…”

Section: Resultsmentioning

confidence: 99%

A systematic review of studies that measure parental vaccine attitudes and beliefs in childhood vaccination

et al. 2020

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Background: Acceptance of vaccines is an important predictor of vaccine uptake. This has public health implications as those who are not vaccinated are at a higher risk of infection from vaccine preventable diseases. We aimed to examine how parental attitudes and beliefs towards childhood vaccination were measured in questionnaires through a systematic review of the literature. Methods: We systematically reviewed the literature to identify primary research studies using tools to measure vaccine attitudes and beliefs, published between January 2012 and May 2018. Studies were included if they involved a quantitative survey of the attitudes and beliefs of parents about vaccinations recommended for children. We undertook a synthesis of the results with a focus on evaluating the tools used to measure hesitancy. Results: A total of 116 studies met the inclusion criteria, 99 used a cross sectional study design, 5 used a case control study design, 4 used a pre-post study design and 8 used mixed methods study designs. Sample sizes of included studies ranged from 49 to 12,259. The most commonly used tool was the Parent Attitudes about Childhood Vaccines (PACV) Survey (n = 7). The most common theoretical framework used was the Health Belief Model (n = 25). Questions eliciting vaccination attitudes and beliefs varied widely. Conclusions: There was heterogeneity in the types of questionnaires used in studies investigating attitudes and beliefs about vaccination in parents. Methods to measure parental attitudes and beliefs about vaccination could be improved with validated and standardised yet flexible instruments. The use of a standard set of questions should be encouraged in this area of study.

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Section: Resultsmentioning

confidence: 99%

A systematic review of studies that measure parental vaccine attitudes and beliefs in childhood vaccination

et al. 2020

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“…This attenuation is achieved either by continuous passage either in vitro or in vivo of the virulent agent by exposing it to unfavorable conditions or by means of genetic manipulation like mutagenesis (e.g., modifying the virus by deleting viral genes essential for replication, host-tropism, immune evasion or invasion or by codon de-optimization) [ 51 , 52 , 53 , 54 , 55 , 56 ]. Several successful human vaccines have been made using this live attenuated vaccine platform including the Bacillus Calmette-Guérin (BCG) vaccine for tuberculosis (TB), the Measles vaccine, oral polio vaccine (OPV), and live attenuated seasonal influenza vaccine [ 54 , 57 , 58 , 59 , 60 , 61 ]. Except for BCG and measles vaccines, an important feature of these live attenuated vaccines is that they can be administered by routes other than parenteral i.e., oral or intranasal routes.…”

Section: Covid-19 (Sars-cov-2) Vaccine Platformsmentioning

confidence: 99%

COVID-19 Vaccines (Revisited) and Oral-Mucosal Vector System as a Potential Vaccine Platform

et al. 2021

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There are several emerging strategies for the vaccination of COVID-19 (SARS-CoV-2) however, only a few have yet shown promising effects. Thus, choosing the right pathway and the best prophylactic options in preventing COVID-19 is still challenging at best. Approximately, more than two-hundred vaccines are being tested in different countries, and more than fifty clinical trials are currently undergoing. In this review, we have summarized the immune-based strategies for the development of COVID-19 vaccines and the different vaccine candidate platforms that are in clinical stages of evaluation, and up to the recently licensed mRNA-based COVID-19 vaccines of Pfizer-BioNtech and Moderna’s. Lastly, we have briefly included the potentials of using the ‘RPS-CTP vector system’ for the development of a safe and effective oral mucosal COVID-19 vaccine as another vaccine platform.

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“…Model have largely informed past assessments of vaccination attitudes, intentions and behaviours. [18][19][20][21][22][23][24][25][26] These expectancy-value theories do not adequately account for the dynamic role of caregivers' repeated experiences in shaping their vaccination behaviours. Recognising these limitations, various international partner organisations, under the leadership of UNICEF, developed the Immunisation Caregiver Journey Framework 27 as a novel way to contextualise and understand how caregivers and families navigate childhood immunisation services, especially in LMIC settings.…”

Section: Towards An Experience-driven Approach Expectancy-value Theories Such As the Health Beliefmentioning

confidence: 99%

Using immunisation caregiver journey interviews to understand and optimise vaccination uptake: lessons from Sierra Leone

et al. 2021

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Quantitative and qualitative assessments have revealed diverse factors that influence the uptake of childhood immunisation services and shed light on reasons for vaccination delays and refusals. UNICEF and partner organisations developed the Immunisation Caregiver Journey Framework as a novel way to understand caregiver experiences in accessing and receiving immunisation services for children. This framework aims to help immunisation programmes identify vaccination barriers and opportunities to improve vaccination uptake by enhancing the overall caregiver journey in a systems-focused manner, using human-centred design principles. In this paper, we adapt the framework into a flexible qualitative inquiry approach with theoretical guidance from interpretative phenomenology. We draw from the implementation experiences in Sierra Leone to inform methodological guidance on how to design and implement the Immunisation Caregiver Journey Interviews (ICJI) to understand the lived experiences of caregivers as they navigate immunisation services for their children. Practical guidance is provided on sampling techniques, conducting interviews, data management, data analysis and the use of data to inform programmatic actions. When properly implemented, the ICJI approach generates a rich qualitative understanding of how caregivers navigate household and community dynamics, as well as primary healthcare delivery systems. We argue that understanding and improving the caregiver journey will enhance essential immunisation outcomes, such as the completion of the recommended vaccination schedule, timeliness of vaccination visits and reduction in dropouts between vaccine doses.

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Acceptability of intranasal live attenuated influenza vaccine, influenza knowledge and vaccine intent in The Gambia

Cited by 16 publications

References 42 publications

A systematic review of studies that measure parental vaccine attitudes and beliefs in childhood vaccination

A systematic review of studies that measure parental vaccine attitudes and beliefs in childhood vaccination

COVID-19 Vaccines (Revisited) and Oral-Mucosal Vector System as a Potential Vaccine Platform

Using immunisation caregiver journey interviews to understand and optimise vaccination uptake: lessons from Sierra Leone

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