Early-life nutritional status and metabolic syndrome: gender-specific associations from a cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

Briskiewicz, Bruna Lucas; Barreto, Sandhi Maria; Amaral, Joana Ferreira do; Diniz, Maria de Fátima Haueisen Sander; Molina, Maria del Carmen Bisi; Matos, Sheila Maria Alvim; Cardoso, Letícia de Oliveira; Velásquez-Meléndez, Gustavo; Schmidt, María Inês; Giatti, Luana

doi:10.1017/s1368980017004256

Cited by 6 publications

(7 citation statements)

References 64 publications

(81 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Finally, 15 published articles with 16 studies were included in this meta-analysis ( 13 – 27 ). All but two studies ( 20 , 27 ) scored 7 points, and the remaining studies scored 5 or 6 points ( Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

“…After reviewing full-text articles, seven articles without OR and/or 95% CI, four articles without relevant outcome, and three reviews were excluded. Finally, 15 published articles with 16 studies were included in this meta-analysis (13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27). All but two studies (20, 27) scored 7 points, and the remaining studies scored 5 or 6 points ( Table 1).…”

Section: Literature Search and Study Characteristicsmentioning

confidence: 99%

“…Seven studies focused on women and men, two only on men, and two only on women. For the association between premature birth and the risk of metabolic syndrome, five articles (19,20,23,24,27) with five studies (four cohort studies and one cross-sectional study) were included, involving 7,295 participants. Among these studies, one was conducted in Europe, two in South America, one in North America, and one in Oceania.…”

Section: Characteristics Of Studiesmentioning

confidence: 99%

“…Many dietary, behavioral, and psychological factors have been confirmed to be associated with metabolic syndrome, such as sugar-sweetened and artificially sweetened beverage intake (10), low levels of physical activity and sedentary behavior (11), and anxiety (12). In recent years, many studies found an association of several perinatal risk factors, such as low birth weight (LBW) and premature birth, with the increased risk of metabolic syndrome, but some others showed contradictory results (13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27). Therefore, this meta-analysis was conducted to evaluate the association of LBW and premature birth with metabolic syndrome.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Association of Low Birth Weight and Premature Birth With the Risk of Metabolic Syndrome: A Meta-Analysis

2020

View full text Add to dashboard Cite

The association of preterm or low birth weight (LBW) with the risk of metabolic syndrome is still unclear. This study aimed to assess the association between preterm or LBW and metabolic syndrome risk according to study or participants' characteristics. PubMed, Web of Science, and EMBASE were searched for epidemiologic studies on the association published up to April 30, 2020. Pooled odds ratio (ORs) and weighted mean differences (WMDs) with 95% confidence intervals (CIs) were calculated using the random-effects model. Low birth weight was associated with an increased risk of metabolic syndrome (OR, 1.37; 95% CI, 1.17-1.61). In the subgroup analysis by study design, the pooled ORs for LBW and metabolic syndrome in the cohort and cross-sectional studies were 1.79 and 1.22. In the subgroup analysis by sex, LBW was found to be associated with an increased risk of metabolic syndrome in pooled studies including both men and women or studies including only women. The association between premature birth and risk of metabolic syndrome was significant in cohort studies (OR, 1.72; 95% CI, 1.12-2.65). Also, LBW or preterm was significantly associated with a higher Homeostasis Model Assessment of Insulin Resistance (WMD, 0.28; 95% CI, 0.19-0.36). Low birth weight and preterm might be risk factors for metabolic syndrome.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Literature Search and Study Characteristicsmentioning

confidence: 99%

Section: Characteristics Of Studiesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Association of Low Birth Weight and Premature Birth With the Risk of Metabolic Syndrome: A Meta-Analysis

2020

View full text Add to dashboard Cite

show abstract

“…Open access some inconsistent findings. 14 15 Moreover, many studies have examined the relationship between birth weight and metabolic syndrome with inconsistent results, [16][17][18] but no studies have investigated the association of LBW with the risk of CMDs. CMDs are complex genetic and lifestyle-related disorders, [19][20][21] and birth weight may also be affected by genetic factors and intrauterine environment.…”

Section: Strengths and Limitations Of This Studymentioning

confidence: 99%

Association of low birth weight with cardiometabolic diseases in Swedish twins: a population-based cohort study

Yang

et al. 2021

BMJ Open

View full text Add to dashboard Cite

ObjectivesTo examine the association between low birth weight (LBW) and cardiometabolic diseases (CMDs, including heart disease, stroke and type 2 diabetes mellitus) in adulthood, and to explore whether genetic, early-life environmental and healthy lifestyle factors play a role in this association.DesignA population-based twin study.SettingTwins from the Swedish Twin Registry who were born in 1958 or earlier participated in the Screening Across the Lifespan Twin (SALT) study for a full-scale screening during 1998–2002 and were followed up until 2014.Participants19 779 twin individuals in Sweden with birthweight data available (mean age: 55.45 years).Primary and secondary outcome measuresCMDs were assessed based on self-reported medical records, medication use and records from the National Patient Registry. A lifestyle index encompassing smoking status, alcohol consumption, exercise levels and Body Mass Index was derived from the SALT survey and categorised as unfavourable, intermediate or favourable. Data were analysed using generalised estimating equation (GEE) models and conditional logistic regression models.ResultsOf all participants, 3998 (20.2%) had LBW and 5335 (27.0%) had incident CMDs (mean age at onset: 63.64±13.26 years). In GEE models, the OR of any CMD was 1.39 (95% CI 1.27 to 1.52) for LBW. In conditional logistic regression models, the LBW–CMD association became non-significant (OR=1.21, 95% CI 0.94 to 1.56). The difference in ORs from the two models was statistically significant (p<0.001). In the joint effect analysis, the multiadjusted OR of CMDs was 3.47 (95% CI 2.72 to 4.43) for participants with LBW plus an unfavourable lifestyle and 1.25 (95% CI 0.96 to 1.62) for those with LBW plus a favourable lifestyle.ConclusionLBW is associated with an increased risk of adult CMDs, and genetic and early-life environmental factors may account for this association. However, a favourable lifestyle profile may modify this risk.

show abstract

Early Life Nutrition and Non Communicable Disease

Heidari‐Beni

2019

Advances in Experimental Medicine and Biology

View full text Add to dashboard Cite

Early-life nutritional status and metabolic syndrome: gender-specific associations from a cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

Abstract: Poor nutritional status as estimated by LBW and lower leg length in childhood was associated with a higher prevalence of MetS, although LBW was a significant factor only among women.

Cited by 6 publications

References 64 publications

Association of Low Birth Weight and Premature Birth With the Risk of Metabolic Syndrome: A Meta-Analysis

Association of Low Birth Weight and Premature Birth With the Risk of Metabolic Syndrome: A Meta-Analysis

Association of low birth weight with cardiometabolic diseases in Swedish twins: a population-based cohort study

Early Life Nutrition and Non Communicable Disease

Contact Info

Product

Resources

About