Predicting falls in multiple sclerosis: Do electrophysiological measures have a better predictive accuracy compared to clinical measures?

Cardiovascular Autonomic Dysfunction and Falls in People With Multiple Sclerosis: Is There a Link? An Opinion Article

“…Furthermore, the importance of recording fall-related circumstances has been emphasized (Hauer et al, 2006;Coote et al, 2014). In this regard, prospective cohort studies conducted in MS populations have often failed to report perceived causes of falling (Chinnadurai et al, 2018;Tajali et al, 2019), which limits the ability to identify precipitating factors. An observational study by Gunn et al (2014) revealed that only 1.8% of recorded falls were directly attributed to dizziness/fainting, as opposed to a much greater proportion of falls that were precipitated by a loss of balance (19.4%) or legs giving way (8.7%).…”

Neurophysiologische Defizite und deren Therapie bei Multipler Sklerose

“…Die pathologischen SEP haben zudem durchaus einen prognostischen Wert: Pathologische SEPs zum Zeitpunkt der Diagnosestellung sind mit einem größeren Risiko verbunden, auch nach 15 Jahren ein höheres Maß an Behinderung und einen rascher progredienten Verlauf zu erleiden [13]. Daneben waren pathologische SEP der unteren Extremität auch mit einer erhöhten Wahrscheinlichkeit assoziiert, in der Zukunft zu stürzen [4]. nur in der Dokumentation von bestehenden Hirnstammschädigungen [12].…”

Protocol for an exploratory, randomised, single-blind clinical trial of aerobic exercise to promote remyelination in multiple sclerosis

“… 20–22 While studies have correlated SSEP latencies to imbalance and fall frequency in pwMS, this will be the first study to examine the associations between SSEP latencies and a panel of mobility metrics in pwMS to inform clinical outcomes for future remyelination clinical trials in pwMS. 23 24 …”