Role of depression in secondary prevention of Chinese coronary heart disease patients receiving percutaneous coronary intervention

Abstract

IntroductionCoronary heart disease (CHD) patients who have undergone percutaneous coronary intervention (PCI) have higher rates of depression than the general population. However, few researchers have assessed the impact of depression on the secondary prevention of CHD in China.ObjectiveThe main purpose of this investigation was to explore the relationship between depression and secondary prevention of CHD in Chinese patients after PCI.MethodsThis descriptive, cross-sectional one-site study recruited both elective and emergency PCI patients one year after discharge. Data from 1934 patients were collected in the clinic using questionnaires and medical history records between August 2013 and September 2015. Depression was evaluated by the 9-item Patient Health Questionnaire. Secondary prevention of CHD was compared between depression and non-depression groups.ResultsWe found that depression affected secondary prevention of CHD in the following aspects: lipid levels, blood glucose levels, smoking status, physical activity, BMI, and rates of medication use.ConclusionsDepressive patients with CHD are at increased risk of not achieving the lifestyle and risk factor control goals recommended in the 2006 AHA guidelines. Screening should focus on patients after PCI because treating depression can improve outcomes by improving secondary prevention of CHD.

Tai Chi Ameliorates Coronary Heart Disease by Affecting Serum Levels of miR-24 and miR-155

“…CHD patients undergoing percutaneous coronary intervention have a higher rate of depression than the general population. Treating depression has proven to be effective in improving outcomes of CHD patients (Feng et al, 2017).…”

The association of depression following percutanous coronary intervention with adverse cardiovascular events

“…Currently, although not all the mechanisms have been recognized, several reasons for the prognostic value of depression in patients undergoing PCI were established. First, depression is closely related to unhealthy lifestyles [24] and compromised adherence to medication for coronary heart disease, [25] which, consequently, contributes to the adverse cardiac events following PCI. Second, from pathophysiological perspective, depression is associated with neuroendocrine dysfunction, inflammation, impaired endothelial function, and nutritional deficiencies.…”

Chinese patients’ clinical and psychosocial outcomes in the 6 months following percutaneous coronary intervention

“…One of the most common acute CVD treatment modalities is percutaneous coronary intervention (PCI). Indeed, an estimated 400,000 PCI procedures are now conducted every year in China, despite their lower resources [ 3 ] (versus ~ 600,000 in the United States for example) [ 4 ]. The high rate [ 3 ] of PCIs performed has led to concerns about the appropriateness, risks and benefits of these procedures in patients who undergo them [ 5 ].…”

“…Indeed, an estimated 400,000 PCI procedures are now conducted every year in China, despite their lower resources [ 3 ] (versus ~ 600,000 in the United States for example) [ 4 ]. The high rate [ 3 ] of PCIs performed has led to concerns about the appropriateness, risks and benefits of these procedures in patients who undergo them [ 5 ]. Indeed, in one study which tracked 1600 Chinese patients who underwent PCI for stable coronary artery disease, they found that 26% of the patients had no pre-procedural angina symptoms [ 6 ].…”