292 Erosive Versus Non Erosive Hand Oa: Prospective Cross-Sectional Comparison of Clinical Data

Maheu, E.; Michon, Mathilde; Carrat, Fabrice; Bérenbaum, Francis

doi:10.1016/s1063-4584(08)60336-2

Cited by 13 publications

(15 citation statements)

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“…Erosive HOA is frequently seen in postmenopausal women visiting rheumatology clinics 25. However, few studies have described the prevalence of erosive HOA in the general population,26 27 and no population-based studies have described its incidence.…”

Section: Introductionmentioning

confidence: 99%

Prevalence, incidence and progression of hand osteoarthritis in the general population: the Framingham Osteoarthritis Study

Haugen

Englund²,

Aliabadi³

et al. 2011

Annals of the Rheumatic Diseases

407

316

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Objectives To describe the prevalence and longitudinal course of radiographic, erosive and symptomatic hand osteoarthritis (HOA) in the general population. Methods Framingham osteoarthritis (OA) study participants obtained bilateral hand radiographs at baseline and 9-year follow-up. The authors defined radiographic HOA at joint level as Kellgren–Lawrence grade (KLG)≥2, erosive HOA as KLG≥2 plus erosion and symptomatic HOA as KLG≥2 plus pain/aching/stiffness. Presence of HOA at individual level was defined as ≥1 affected joint. The prevalence was age-standardised (US 2000 Population 40–84 years). Results Mean (SD) baseline age was 58.9 (9.9) years (56.5% women). The age-standardised prevalence of HOA was only modestly higher in women (44.2%) than men (37.7%), whereas the age-standardised prevalence of erosive and symptomatic OA was much higher in women (9.9% vs 3.3%, and 15.9% vs 8.2%). The crude incidence of HOA over 9-year follow-up was similar in women (34.6%) and men (33.7%), whereas the majority of those women (96.4%) and men (91.4%) with HOA at baseline showed progression during follow-up. Incident metacarpophalangeal and wrist OA were rare, but occurred more frequently and from an earlier age in men than women. Development of erosive disease occurred mainly in those with non-erosive HOA at baseline (as opposed to those without HOA), and was more frequent in women (17.3%) than men (9.6%). Conclusions The usual female predominance of prevalent and incident HOA was less clear for radiographic HOA than for symptomatic and erosive HOA. With an ageing population, the impact of HOA will further increase.

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Section: Introductionmentioning

confidence: 99%

Prevalence, incidence and progression of hand osteoarthritis in the general population: the Framingham Osteoarthritis Study

Haugen

Englund²,

Aliabadi³

et al. 2011

Annals of the Rheumatic Diseases

407

316

View full text Add to dashboard Cite

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“…Maheu et al 8 showed that patients with EOA reported more functional limitations, more aesthetic damage, similar HRQL and similar pain levels compared with those with non-EOA. This last finding is in contrast with our results, which may be due to a difference in outcome measures.…”

Section: Discussionmentioning

confidence: 99%

“…EOA is a radiographic subset based on the presence of subchondral erosions which lead to deformities and sometimes to bony ankylosis 7. Although it is assumed that EOA has a higher clinical burden and worse outcome than non-EOA, there are very few studies on this topic 8 9. In addition, the relationship between EOA and the presence of nodes is unclear.…”

Section: Introductionmentioning

confidence: 99%

Clinical burden of erosive hand osteoarthritis and its relationship to nodes

Bijsterbosch

Watt

Meulenbelt

et al. 2010

Annals of the Rheumatic Diseases

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“…12 We also noted that esthetic damage was much higher in patients with at least two erosive joints on radiography versus those with none. 13 In a particular study or trial, the clinical instru ment that might best reflect a patient's status (from the patient's perspective) and disease activity or severity has not yet been determined, and will probably depend upon the goal of the study and the patient population. In a rando mized, placebocontrolled trial of a symptom modifying drug by Kvien and colleagues, 14 the most responsive outcomes were the patient global assessment and pain evaluation on a VAS.…”

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confidence: 99%