Características de los pacientes con derrame pleural mielomatoso. Revisión sistemática

Riveiro, Vanessa; Ferreiro, Lucía; Toubes, María E.; Lama, Adriana; Álvarez-Dobaño, José Manuel; Valdés, Luís

doi:10.1016/j.rce.2017.11.001

Cited by 14 publications

(4 citation statements)

References 66 publications

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“…A systemic review in characteristics of 153 patients with MPE was reported in 2018 by Riveiro et al [4]. The median age was 62 years and male predominant (1.7:1).…”

Section: Discussionmentioning

confidence: 99%

“…In most cases of MPE, the pleural fluid profile is lymphocytic (78.6%) exudate (97.4%) [4]. The most common subtype in a study of 23 patients with MPE by Zhong et al was IgA- Kappa (39%), followed by Lambda-light chain (26%), IgG- Kappa (13%), non-secrete (13%) and Kappa-light chain MM (9%) [5].…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, MPE is associated with poorer treatment response. Bortezomib-based therapy combines with local therapy (thoracentesis, chest drainage or pleurodesis) can achieved the best response in MPE patients [4,9,10]. In a study of HJ Kim et al (based on Vincristine, Adriamycin, Dexamethasone regimen), MPE disappeared in a 58% of patient who received chemotherapy, which median response duration (defined as days from disappearance to relapse of MPE) was 123 days, compared with 5.7 month in a study of Zhong et al (based on Bortezomib regimen) [5,11].…”

Section: Discussionmentioning

confidence: 99%

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Massive pleural effusion due to IgG-Kappa subtype multiple myeloma: A case report

Arunsurat

Reechaipichitkul

So-ngern

et al. 2020

Respiratory Medicine Case Reports

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Multiple myeloma (MM) is a hematologic malignancy of plasma cell origin. Incidence of pleural effusion in multiple myeloma patients is approximately 6%. Myelomatous pleural effusions (MPE) are rare and occur in less than 1% of all MM cases. MPE is associated with advanced diseases, decreased survival time, and poor treatment response.In our case report, we describe a 59-year old man who presented with MPE at the initial diagnosis of MM. A diagnosis of MPE was reach through pleural fluid cytology and pleural tissue histology. The MPE had good response to initial dexamethasone without local therapy.

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“…A systemic review in characteristics of 153 patients with MPE was reported in 2018 by Riveiro et al [4]. The median age was 62 years and male predominant (1.7:1).…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Massive pleural effusion due to IgG-Kappa subtype multiple myeloma: A case report

Arunsurat

Reechaipichitkul

So-ngern

et al. 2020

Respiratory Medicine Case Reports

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“…MPE was predominantly unilateral (63.9%) and usually involved more than two-third of hemithorax (54.5%). In most cases of MPE, the pleural fluid profile is lymphocytic (78.6%) and exudate (97.4%) [ 11 , 12 ]. Upon literature review of English case reports about pleural effusion and MM, there were 17 cases of MPE as initial presentation of MM.…”

Section: Discussionmentioning

confidence: 99%

Transient Pleural Fluid Infiltration by Clonal Plasma Cells Associated with Pulmonary Tuberculosis

et al. 2020

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Pleural effusion is a rare presentation of plasma cell myeloma, occurring in around 6% of patients during the course of their disease, most commonly as a consequence of a concurrent disease process like heart failure secondary to amyloid deposition. Direct infiltration of the pleural fluid by malignant cells leading to myelomatous pleural effusion is a rare mechanism occurring in less than 1% of patients with plasma cell myeloma, and it is associated with a worse prognosis. There are few case reports of myelomatous pleural effusion as an initial presentation of multiple myeloma. Pleural fluid infiltration by monoclonal plasma cells in the absence of an underlying plasma cell myeloma was not reported before in the literature. Tuberculosis is a known cause of polyclonal gammaglobulinemia, however few case reports described the coexistence of monoclonal gammopathy of undetermined significance and tuberculosis. Here we present an interesting case of pleural fluid infiltration by an abnormal looking clonal plasma cells associated with active pulmonary tuberculosis and parapneumonic effusion in a patient with a background of acute myeloid leukemia. Interestingly, the clonal plasma cell proliferation was confined to the pleural fluid without any evidence of an underlying plasma cell neoplasms (including monoclonal gammopathy of undetermined significance and plasmacytomas). Since our patient had an underlying meyloid neoplasm, we though about the possibility of secondary malignancy. However, in almost all patients with coexisting

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Extramedullary Multiple Myeloma With Pleural Involvement: A Rare Clinical Entity

Velasco-Álvarez

Gorospe‐Sarasúa

Fra-Fernández

et al. 2019

Archivos de Bronconeumología (English Edition)

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Características de los pacientes con derrame pleural mielomatoso. Revisión sistemática

Cited by 14 publications

References 66 publications

Massive pleural effusion due to IgG-Kappa subtype multiple myeloma: A case report

Massive pleural effusion due to IgG-Kappa subtype multiple myeloma: A case report

Transient Pleural Fluid Infiltration by Clonal Plasma Cells Associated with Pulmonary Tuberculosis

Extramedullary Multiple Myeloma With Pleural Involvement: A Rare Clinical Entity

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