Novel Parameter to Predict Left Ventricular Filling Pressure: Product of Log B-Type Natriuretic Peptide and Ratio of Mitral Inflow Early and Late Diastolic Filling Velocities

Oikawa, Masayoshi; Kobayashi, Atsushi; Wada, Kento; Sato, Toshio; Suzuki, Satoshi; Yoshihisa, Akiomi; Nakazato, Kazuhiko; Suzuki, Hitoshi; Saitoh, Shu‐ichi; Ishida, Takafumi; Takeishi, Yasuchika

doi:10.1016/j.cardfail.2017.10.008

Cited by 4 publications

(2 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Oikawa et al. 26 reported that multiplying lnBNP and the ratio of the mitral inflow early- and late-diastolic filling velocities is a useful parameter for detecting elevated pulmonary capillary wedge pressure regardless of the left ventricular ejection fraction. Zhou et al.…”

Section: Discussionmentioning

confidence: 99%

“…Mentias et al 25 reported that a higher lnBNP level was significantly associated with increased mortality in asymptomatic patients with mitral regurgitation and a preserved left ventricular ejection fraction. Oikawa et al 26 reported that multiplying lnBNP and the ratio of the mitral inflow early-and late-diastolic filling velocities is a useful parameter for detecting elevated pulmonary capillary wedge pressure regardless of the left ventricular ejection fraction. Zhou et al 27 reported that lnBNP is an independent risk factor for contrastinduced acute kidney injury in patients with acute myocardial infarction.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Log-transformed B-type natriuretic peptide as a prognostic predictor in patients undergoing cardiovascular surgery

et al. 2018

View full text Add to dashboard Cite

ObjectiveThis study was performed to explore the association between circulating B-type natriuretic peptide (BNP) and other mortality-related factors in patients undergoing cardiovascular surgery.MethodsIn this observational study, multilevel linear regression analysis and multilevel survival analysis were performed to measure the log-transformed BNP (lnBNP) value at four time points in 197 patients with 788 repeated data measurements. Effects of the interaction between the time points and the two intervention groups (cardiac surgery and vascular surgery) were also investigated. Six models were evaluated to identify the best fit for the data. Stata/MP® version 14.2 (Stata Corp., College Station, TX, USA) was used to analyze the two-level variance component model fitting.ResultsThere were significant differences in the fixed-effect parameters of lnBNP, such as the time point, age, body mass index, emergency operation, prognostic nutritional index, and estimated glomerular filtration rate. According to the multilevel survival analysis for all-cause death and vascular death, lnBNP significantly differed and was a common prognostic marker.ConclusionAs lnBNP increased by 1 point, all-cause death increased 2.07 times and vascular death increased 3.10 times. lnBNP is an important prognostic predictor and quantitative biochemical marker in patients undergoing cardiovascular surgery.

show abstract

Section: Discussionmentioning

confidence: 99%