Negative Affect Is Associated With Higher Risk of Incident Cognitive Impairment in Nondepressed Postmenopausal Women

Korthauer, Laura E.; Goveas, Joseph S.; Espeland, Mark A.; Shumaker, Sally A.; Garcia, Katelyn; Tindle, Hilary A.; Salmoirago‐Blotcher, Elena; Sink, Kaycee M.; Vaughan, L. C.; Rapp, Stéphen R.; Resnick, Susan M.; Driscoll, Ira

doi:10.1093/gerona/glx175

Cited by 19 publications

(21 citation statements)

References 45 publications

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“…Many studies have shown a relationship between cognitive errors and negative emotions, such as depression, and the cognitive behavioral therapy for treating negative emotions has also been recognized as effective [46,47,48]. In addition, the relationship between cognitive deficit and negative affect, such as depression, has been confirmed [49]. Patients with depression are unable to appropriately appreciate the future because they have rigid thoughts, which has been shown to affect emotional acceptance [48,50].…”

Section: Discussionmentioning

confidence: 99%

The Mediating Effects of Affect on Associations between Impulsivity or Resilience and Internet Gaming Disorder

Shin

Choi

Lee

et al. 2019

JCM

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Internet gaming disorder (IGD) is a new disease proposed by the Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition (DSM-5), and has been studied extensively in relation to depression and impulsivity. The relationship between resilience and disease has been found in a variety of addictive disorders, but studies on IGD are lacking. In this study, 71 IGD patients and 78 healthy controls (HCs) were recruited. Impulsivity, resilience, affects, and the degree of internet game addiction were measured using formal tools. The measured values were analyzed by mediation analysis to evaluate the mediating role of affects on resilience and impulsivity related to IGD symptoms. The IGD group showed higher impulsivity, lower resilience, lower positive affect, and higher negative affect than the HC group. The mediation analysis showed that a positive affect was a mediator between impulsivity and the severity of addiction in both groups. Negative affect mediated impulsivity/resilience and the severity of addiction only in the IGD group. Although the results of this study are based on a narrow category of subjects, who are young male adults around 25 years of age, the results suggest that positive affect can be strengthened to prevent the IGD illness, and that illness symptoms may be alleviated by reducing negative affect.

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Section: Discussionmentioning

confidence: 99%

The Mediating Effects of Affect on Associations between Impulsivity or Resilience and Internet Gaming Disorder

Shin

Choi

Lee

et al. 2019

JCM

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“…Conscientiousness, in contrast, while not an emotional trait by definition, is associated consistently with lower negative affect, particularly less stress (Ebstrup, Eplov, Pisinger, & Jørgensen, 2011), lower stressor-related negative affect (Leger, Charles, Turiano, & Almeida, 2016), and faster recovery from stress (Javaras et al, 2012). Negative affect, in turn, increases dementia risk (Korthauer et al, 2018).…”

Section: Negative Affectmentioning

confidence: 99%

“…These studies are limited by their cross-sectional design or sole focus on Neuroticism. Parallel literatures have documented the predictive power of cognitive engagement (Wang, MacDonald, Dekhtyar, & Fratiglioni, 2017), negative affect (Korthauer et al, 2018), subjective health (Montlahuc et al, 2011), and social integration (Wilson, Krueger, et al, 2007) on cognitive outcomes. As described in the following, these potential mechanisms have been associated with personality and may be additional pathways that help explain the association with cognition.…”

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confidence: 99%

Evaluations of a Previous Day as a Pathway Between Personality and Healthy Cognitive Aging

et al. 2019

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Objective: To examine the association between Five-Factor Model personality traits and how individuals evaluate a recent day in their lives (yesterday) and whether these evaluations mediate personality and cognitive function over time. Methods: Participants were a subsample from the Health and Retirement Study who completed personality measures in 2008/2010, the day evaluation in 2011, and cognitive tasks in 2012 ( N = 3,454). Results: Lower Neuroticism and Higher Extraversion, Openness, Agreeableness, and Conscientiousness were associated with a more engaging day, fewer negative feelings, better subjective health, and less time spent alone. Active engagement and subjective health were associated with cognitive function and mediated the prospective associations between Neuroticism, Openness, and Conscientiousness and cognitive function. Discussion: Personality is associated with how individuals evaluated their previous day, which contributes to cognition over time. The present research contributes to a mechanistic model that aims to identify pathways through which personality contributes to cognitive aging.

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“…Life satisfaction predicted dementia in a sample of 1.751 elderly people without cognitive impairment at baseline who were followed for 5 years (adjusted OR = 0.70, CI = 0.51–0.96; Peitsch et al, 2016 ). This dementia risk is also related to negative affects according to a study conducted by Korthauer et al (2017) . The authors assessed affects in 2,137 elderly women without depressive symptoms who were followed for 11 years and concluded that negative affects were associated with greater cognitive decline, even when adjusting for the covariates of age, education, lifestyle, sociodemographic factors, global cognition, cardiovascular risk, and hormone therapy.…”

Section: Introductionmentioning

confidence: 95%

Association of Lower Spiritual Well-Being, Social Support, Self-Esteem, Subjective Well-Being, Optimism and Hope Scores With Mild Cognitive Impairment and Mild Dementia

et al. 2018

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Introduction: Positive psychology (PP) constructs contribute significantly to a better quality of life for people with various diseases. There are still few studies that have evaluated the evolution of these aspects during the progression of dementia.Objective: To compare the scores for self-esteem, life satisfaction, affect, spirituality, hope, optimism and perceived support network between elderly people with mild cognitive impairment (MCI), mild dementia and moderate dementia and control group.Methods: Cross-sectional study. The sample consisted of 66 healthy controls, 15 elderly people with MCI, 25 with mild dementia and 22 with moderate dementia matched by age, gender, and schooling. The instruments used were: Spirituality Self Rating Scale (SSRS), Rosenberg Self-Esteem Scale, Medical Outcomes Study’s Social Support Scale, Life Satisfaction Scale (LSS), Positive and Negative Affect Schedule (PANAS), Revised Life Orientation Test (LOT-R), and Adult Dispositional Hope Scale (ADHS).Results: The scores for spiritual well-being, social support, self-esteem, life satisfaction, positive affect, optimism, negative affect, and hope differed significantly between the groups (p < 0.05). The individuals with MCI and mild dementia had lower spiritual well-being, social support, self-esteem, life satisfaction, positive affect, optimism and hope scores, and higher negative affect scores compared with the controls. The scores for PP constructs did not differ between the group of people with moderate dementia and the control group.Conclusion: Dementia was found to impact several PP constructs in the early stages of the disease. For individuals with greater cognitive impairment, anosognosia appears to suppress the disease’s impact on these constructs.

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Negative Affect Is Associated With Higher Risk of Incident Cognitive Impairment in Nondepressed Postmenopausal Women

Abstract: We present the first evidence to date that greater NA, even in the absence of elevated depressive symptoms, is associated with higher risk of MCI and dementia. This suggests that NA may be an important, measureable and potentially modifiable risk factor for age-related cognitive decline.

Cited by 19 publications

References 45 publications

The Mediating Effects of Affect on Associations between Impulsivity or Resilience and Internet Gaming Disorder

The Mediating Effects of Affect on Associations between Impulsivity or Resilience and Internet Gaming Disorder

Evaluations of a Previous Day as a Pathway Between Personality and Healthy Cognitive Aging

Association of Lower Spiritual Well-Being, Social Support, Self-Esteem, Subjective Well-Being, Optimism and Hope Scores With Mild Cognitive Impairment and Mild Dementia

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