Feline sarcoid in a 1-year-old domestic short-haired cat caused by bovine papillomavirus type 14 in Switzerland

Abstract

A 1-year-old domestic short haired cat, living on a farm in Switzerland, was presented to the veterinarian with a 5 cm in diameter mass, bulging from her left nostril. The mass was only incompletely removed because of its unfavourable location. Histologically, the lesion consisted of an infiltrative growing spindeloid proliferation in close approximation to the epidermis and was diagnosed as a feline sarcoid tumour. The presence of Bovine Papillomavirus type 14 (BPV-14) specific DNA could be identified in the tissue by using two PCR assays. The amplified sequences of 194 and 549 base pairs (bp) were 99% and 100% identical with a virus isolated after autopsy, from a cat with feline sarcoid in the USA. The cat recovered completely after an even incomplete surgical excision and no recurrence could be observed 10 months later. SummaryA 1year old domestic short haired cat, living on a farm in Switzerland, was presented to the veterinarian with a 5 cm in diameter mass, bulging from her left nostril. The mass was only incompletely removed because of its unfavourable location. Histologically, the lesion con sisted of an infiltrative growing spindeloid proliferation in close approximation to the epidermis and was diag nosed as a feline sarcoid tumour. The presence of Bovine Papillomavirus type 14 (BPV14) specific DNA could be identified in the tissue by using two PCR assays. The amplified sequences of 194 and 549 base pairs (bp) were 99% and 100% identical with a virus isolated after aut opsy, from a cat with feline sarcoid in the USA. The cat recovered completely after an even incomplete surgical excision and no recurrence could be observed 10 months later.

Feline sarcoid: case report

“…The macroscopic description of the tumor of this case corroborates with the characterizations from other studies of sarcoid in cats (GREENWOOD; CAMPBELL; MOVASSEGHI, 2019; HANNA; DUNN, 2003;KIEFER et al, 2017;MACEDO et al, 2012;TEIFKE et al, 2003).…”

“…Metastatic processes were not identified and the surgical excision of the nodule was efficient for the treatment of the reported cat, without relapses over the course of 11 months after the procedure, as stated by other authors (HANNA;DUNN, 2003;KIEFER et al, 2017;MACEDO et al, 2012;TEIFKE et al, 2003). However, despite the feline sarcoid being described as non-metastatic, cases of relapses after the surgical excision of this neoplasia in cats have been reported (BRANDES; LENDL; TEIFKE, 2014; GREENWOOD; CAMPBELL; MOVASSEGHI, 2019; KIEFER et al, 2017; MUNDAY et al, 2015b).…”

“…Indeed, the cat of the present report lived and had access to surrounding areas inhabited by cattle and horses, being, supposedly, susceptible to the infection by the BPV. Although it was not carried out in this study, it would be fundamental the confirmation of the involvement of this virus through the identification of its DNA by means of the Polymerase Chain Reaction (PCR), as carried out in studies of sarcoid in cats and lions in other countries (GREENWOOD;CAMPBELL;MOVASSEGHI, 2019;KIEFER et al, 2017;MUNDAY et al, 2015b;ORBELL;YOUNG;MUNDAY, 2011).…”

“…It is believed that the direct contact with cattle and horses, infected by the papillomavirus (PV), is the main risk factor involved in the development of the sarcoid in felines (SCHULMAN; KRAFFT;JANCZEWSHI, 2001;TEIFKE et al, 2003), considering that this neoplasia is reported, mainly, in cats which reside in the rural area (GROSS et al, 2009;KIEFER et al, 2017;MUNDAY et al, 2015b).…”

Bilateral mastocytic and fibroblastic nodular proliferative dermatosis affecting ear margins in three domestic cats

“…Although the lesions macroscopically resembled sarcoids, histopathological results were incompatible with that diagnosis. 1 Tissue PCR analysis for papillomavirus was performed for all cases, which unlike immunohistochemical analysis is independent of virus replication. 2 Results were negative, so a viral papillomatosis was considered unlikely.…”