In vivo safety evaluation of antibacterial silver chloride nanoparticles from Streptomyces exfoliatus ICN25 in zebrafish embryos

Anti-cancer, Anti-invasiveness & Anti-metastasis of Green Engineered Bioorganic-Capped Silver Nanoparticles Fabricated from Juniperus chinensis Extract and Comparison to Cisplatin in Lung Cancer Cells (A549): In Vitro Assessment of Cellular and Molecular Pathways

“…Various in vitro reports indicates that biogenic AgNPs decreased the mRNA and protein expression of MMP-2 and MMP-9 in wounded granulation tissues [27]. A huge amount of studies show treating MCF-7 cancer cells with AgNPs induces apoptosis by inducing the release of cytochrome c, production of reactive oxygen species [1], and activation of the caspase-3 pathway [28].…”

“…The synthesis of AgNPs was measured using a UV-1800UV-spectrophotometer (Shimadzu, Japan). The particles size, morphology and distribution were detected using scanning electron microscopy [1] (LEO SEM 1450VP, UK) and transmission electron microscopy [8] (FEI 5022/22 Tecnai G2 20 STwin, CR) and Energy Dispersive Spectroscopy (EDS).…”

“…[2]. Recently AgNPs thanks to their marvelous and unparalleled nano-related features, have been applied extensively in different elds of science especially in biomedical eld and have also been studied for their antimicrobial effects [1], wound healing [3] and anticancer [4] activity. A variety of procurement techniques are utilized for the synthesis of silver nanoparticles, among these methods, the usage of plant extracts are more attractive due to the availability of more biological entities, eco-friendly procedures, cost-effective, abundantly renewable, and safe nature for human therapeutic use [5].…”

Green synthesis of silver chloride nanoparticles using Rhodotorula Mucilaginosa

“…Green synthesis of silver chloride nanoparticles has been reported to be mediated by different kinds of organisms, from bacteria to plant extracts. Cell-free culture supernatant of Streptomyces strain, Klebsiella planticola, biomass of Bacillus subtilis, leaf extract of Cissus quadrangularis, aqueous extract of Sargassum plagiophyllum, extract from needles of Pinus densiflora, Prunus persica L. outer peel extract are just a few examples of organisms able to synthesize AgCl NPs [2]- [8].…”

“…The antibacterial effect of biosynthesized AgCl NPs investigated against Escherichia coli was found to be dose-dependent [6]. The biosynthesized silver chloride nanoparticles exhibited besides the antimicrobial activity, cytotoxicity activity against HeLa and SiHa cancer cell lines [2]. M. Sophocleous and J. K. Atkinson have described in their review the significant development of Ag/AgCl screen printed sensors [10].…”