Abstract:Aim: This 3-year report of a prospective long-term cohort investigation aimed to evaluate the clinical and radiographic outcomes of a one-piece zirconia oral implant for single-tooth replacement.
Materials and Methods:Sixty-five patients received a 1-stage implant surgery with immediate temporization. Standardized radiographs were taken at implant insertion, after 1 year, and after 3 years to monitor peri-implant bone levels. A univariate analysis of the association of different baseline parameters on marginal… Show more
“…34 In the peri-implant mucosa of zirconia ceramic implants, zirconia elements have been detected as well, however the origin and influence of metal or ceramic ions or particles on peri-implantitis remains unclear. 17 Furthermore, the host-response and interaction between lymphocyte-and monocyte-macrophage lineage as well as the influence of nano-and microparticles on the microbial biofilm and cytokine release in peri-implant inflammation is not elucidated and future studies could shed more light on the etiological discussion. 9 Within this study, the first histological comparison of human peri-implantitis lesions around ceramic and titanium implants was performed.…”
Section: Discussionmentioning
confidence: 99%
“…Influence of metal particles and ions on peri‐implant biofilm and their possible role in the development, formation and production of extracellular polysaccharides is discussed in current research 34 . In the peri‐implant mucosa of zirconia ceramic implants, zirconia elements have been detected as well, however the origin and influence of metal or ceramic ions or particles on peri‐implantitis remains unclear 17 . Furthermore, the host‐response and interaction between lymphocyte‐ and monocyte‐macrophage lineage as well as the influence of nano‐ and microparticles on the microbial biofilm and cytokine release in peri‐implant inflammation is not elucidated and future studies could shed more light on the etiological discussion 9 …”
Section: Discussionmentioning
confidence: 99%
“…15 Currently, there are mainly one-piece implants on the dental market, however more and more two-piece ceramic implants are available. [16][17][18] To produce a roughened zirco-nia surface, sintering particles onto the implant surface, nanotechnology, laser technology, sandblasting, or sandblasting and acid etching with a mixture of hydrofluoric and sulfuric acid have been used leading to different manufacturer dependent microtopographys. 19 Y-TZP has been described to exhibit various benefits including excellent biocompatibility.…”
Section: Introductionmentioning
confidence: 99%
“…Three zirconia‐containing ceramic systems are established in implant dentistry: yttrium‐stabilized tetragonal zirconia polycrystals (Y‐TZP), alumina‐toughened zirconia (ATZ) and zirconia‐toughened alumina (ZTA) 15 . Currently, there are mainly one‐piece implants on the dental market, however more and more two‐piece ceramic implants are available 16–18 . To produce a roughened zirconia surface, sintering particles onto the implant surface, nanotechnology, laser technology, sandblasting, or sandblasting and acid etching with a mixture of hydrofluoric and sulfuric acid have been used leading to different manufacturer dependent microtopographys 19 .…”
Background: Aim of the pilot study was the histologic classification of the inflamed peri-implant soft tissue around ceramic implants (CI) in comparison with titanium implants (TI). Methods: Peri-implant tissue were retrieved from 15 patients (aged 34 to 88 years, seven males/eight females) with severe peri-implantitis (eight CI, seven TI). The peri-implant soft tissue samples were retrieved from the sites during scheduled removal of the implant and prepared for immunohistochemical analysis. Monoclonal antibodies (targeting CD3, CD20, CD138, and CD68) were used to identify T-and B-cells, plasma cells and macrophages. Quantitative assessment was performed by one histologically trained investigator. Linear mixed regression models were used. Results: A similar numerical distribution of the cell population was found in peri-implantitis around CI compared with TI. CD3 (TI, 17% to 85% versus CI, 20% to 70% of total cell number) and CD138 (TI, 1% to 73% versus CI, 12% to 69% of total cell number) were predominantly expressed. Notably, patient-individual differences of numerical cell distribution were detected. Co-localization of Band T-lymphocytes was observed. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
“…34 In the peri-implant mucosa of zirconia ceramic implants, zirconia elements have been detected as well, however the origin and influence of metal or ceramic ions or particles on peri-implantitis remains unclear. 17 Furthermore, the host-response and interaction between lymphocyte-and monocyte-macrophage lineage as well as the influence of nano-and microparticles on the microbial biofilm and cytokine release in peri-implant inflammation is not elucidated and future studies could shed more light on the etiological discussion. 9 Within this study, the first histological comparison of human peri-implantitis lesions around ceramic and titanium implants was performed.…”
Section: Discussionmentioning
confidence: 99%
“…Influence of metal particles and ions on peri‐implant biofilm and their possible role in the development, formation and production of extracellular polysaccharides is discussed in current research 34 . In the peri‐implant mucosa of zirconia ceramic implants, zirconia elements have been detected as well, however the origin and influence of metal or ceramic ions or particles on peri‐implantitis remains unclear 17 . Furthermore, the host‐response and interaction between lymphocyte‐ and monocyte‐macrophage lineage as well as the influence of nano‐ and microparticles on the microbial biofilm and cytokine release in peri‐implant inflammation is not elucidated and future studies could shed more light on the etiological discussion 9 …”
Section: Discussionmentioning
confidence: 99%
“…15 Currently, there are mainly one-piece implants on the dental market, however more and more two-piece ceramic implants are available. [16][17][18] To produce a roughened zirco-nia surface, sintering particles onto the implant surface, nanotechnology, laser technology, sandblasting, or sandblasting and acid etching with a mixture of hydrofluoric and sulfuric acid have been used leading to different manufacturer dependent microtopographys. 19 Y-TZP has been described to exhibit various benefits including excellent biocompatibility.…”
Section: Introductionmentioning
confidence: 99%
“…Three zirconia‐containing ceramic systems are established in implant dentistry: yttrium‐stabilized tetragonal zirconia polycrystals (Y‐TZP), alumina‐toughened zirconia (ATZ) and zirconia‐toughened alumina (ZTA) 15 . Currently, there are mainly one‐piece implants on the dental market, however more and more two‐piece ceramic implants are available 16–18 . To produce a roughened zirconia surface, sintering particles onto the implant surface, nanotechnology, laser technology, sandblasting, or sandblasting and acid etching with a mixture of hydrofluoric and sulfuric acid have been used leading to different manufacturer dependent microtopographys 19 .…”
Background: Aim of the pilot study was the histologic classification of the inflamed peri-implant soft tissue around ceramic implants (CI) in comparison with titanium implants (TI). Methods: Peri-implant tissue were retrieved from 15 patients (aged 34 to 88 years, seven males/eight females) with severe peri-implantitis (eight CI, seven TI). The peri-implant soft tissue samples were retrieved from the sites during scheduled removal of the implant and prepared for immunohistochemical analysis. Monoclonal antibodies (targeting CD3, CD20, CD138, and CD68) were used to identify T-and B-cells, plasma cells and macrophages. Quantitative assessment was performed by one histologically trained investigator. Linear mixed regression models were used. Results: A similar numerical distribution of the cell population was found in peri-implantitis around CI compared with TI. CD3 (TI, 17% to 85% versus CI, 20% to 70% of total cell number) and CD138 (TI, 1% to 73% versus CI, 12% to 69% of total cell number) were predominantly expressed. Notably, patient-individual differences of numerical cell distribution were detected. Co-localization of Band T-lymphocytes was observed. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
“…Several studies have confirmed stable peri‐implant bone levels around zirconia implants (Kniha et al, ; Pieralli, Kohal, Jung, et al, ). For specific zirconia implants, however, marginal bone loss was remarkably high (Kohal, Schwindling, Bächle, & Spies, ; Kohal, Spies, Bauer, & Butz, ). Early detection of bone lesions around implants is, therefore, as important for zirconia implants as it is for titanium implants.…”
Within the limitations of an in vitro study, IR can be recommended as the initial imaging method for evaluating peri-implant bone defects at zirconia implants. CBCT provides higher diagnostic accuracy of defect classification at the expense of higher cost and radiation dose. Dental MRI may be a promising imaging method for evaluating peri-implant bone defects at zirconia implants in the future.
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