Aim: This 3-year report of a prospective long-term cohort investigation aimed to evaluate the clinical and radiographic outcomes of a one-piece zirconia oral implant for single-tooth replacement. Materials and Methods:Sixty-five patients received a 1-stage implant surgery with immediate temporization. Standardized radiographs were taken at implant insertion, after 1 year, and after 3 years to monitor peri-implant bone levels. A univariate analysis of the association of different baseline parameters on marginal bone loss from implant insertion to 36 months was performed. Soft-tissue parameters were evaluated at prosthesis insertion, after 6 months, after 1 year, and at the 3-year follow-up. Results:After 3 years, six posterior site implants were lost, giving a cumulative survival rate of 90.8%. The mean marginal bone loss was 1.45 mm; 35% of the implants lost at least 2 mm bone, and 22% more than 3 mm. The univariate analysis did not identify any parameter associated with marginal bone loss. Probing depth, clinical attachment level, and bleeding index increased over 3 years, and plaque index decreased. Conclusions:The low survival rate of the presented ceramic implant and especially the high frequency of advanced bone loss are noticeable but remain unexplained. K E Y W O R D Sclinical investigation, oral implants, prospective, zirconia
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