Presentation, clinical features, and results of intervention in upper extremity fibromuscular dysplasia

Abstract

Presenting symptoms for patients with UE FMD vary in severity from asymptomatic disease to digital ischemia. More than half of symptomatic limbs eventually require at least one invasive intervention for complete relief of symptoms.

First International Consensus on the diagnosis and management of fibromuscular dysplasia

“…4,91 It is most commonly of the multifocal type with the majority of patients having both asymptomatic and bilateral involvement. 91 Symptoms of upper extremity FMD may include finger or hand ischemia (rest pain, discoloration, ulceration or gangrene) from thromboembolism or dissection and hand or arm claudication. [91][92][93][94] Other manifestations include Raynaud's phenomenon, paresthesia, and rarely aneurysms.…”

“…91 Symptoms of upper extremity FMD may include finger or hand ischemia (rest pain, discoloration, ulceration or gangrene) from thromboembolism or dissection and hand or arm claudication. [91][92][93][94] Other manifestations include Raynaud's phenomenon, paresthesia, and rarely aneurysms. [91][92][93][94] Brachial bruit and discrepant arm blood pressures are frequently identified on physical exam when brachial FMD is present.…”

“…[91][92][93][94] Other manifestations include Raynaud's phenomenon, paresthesia, and rarely aneurysms. [91][92][93][94] Brachial bruit and discrepant arm blood pressures are frequently identified on physical exam when brachial FMD is present. 91 Diagnostic approach and imaging for FMD at other locations.…”

“…[91][92][93][94] Brachial bruit and discrepant arm blood pressures are frequently identified on physical exam when brachial FMD is present. 91 Diagnostic approach and imaging for FMD at other locations. To date, no studies have compared the accuracy of diagnostic imaging modalities for visceral, lower, or upper extremity FMD.…”

Hemorrhagic Retinopathy and Optic Nerve Sheath Hemorrhage Associated With Fatal Subarachnoid Hemorrhage from a Ruptured Intracranial Aneurysm Due to Segmental Fibromuscular Dysplasia

“…Fibromuscular dysplasia (FMD)—an obscure, rare, segmental, nonatheromatous, and noninflammatory arterial disease—commonly affects women and causes stenosis of medium‐sized arteries . Typically, FMD involves the renal artery followed by the extracranial segments of the internal carotid and vertebral arteries, but it also has been reported in other arteries . The pathogenesis of FMD is unknown.…”