Comparative Analysis of Retinal Reattachment Surgery With or Without Internal Limiting Membrane Peeling to Prevent Postoperative Macular Pucker

Forlini, Matteo; Date, Purva; Ferrari, Luisa Micelli; Lorusso, Massimo; Lecce, Gabriella; Verdina, Tommaso; Neri, Giovanni; Benatti, Caterina; Rossini, Paolo Maria; Bratu, Adriana; DʼEliseo, Domenico; Ferrari, Tommaso Micelli; Cavallini, Gian Maria

doi:10.1097/iae.0000000000001775

Cited by 38 publications

(53 citation statements)

References 18 publications

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“…Similarly, Garweg et al [ 8 ], Foveau et al [ 10 ], Blanco-Teijeiro et al [ 11 ] and Aras et al [ 9 ] included only macula off RD. The rate of macula off RD recorded by Rao et al [ 7 ], Nam et al [ 3 ], Akiyama et al [ 5 ] and Forlini et al [ 4 ] was 74%, 44%, 42% and 68%, respectively. Eissa et al [ 6 ], Garweg et al [ 8 ] and Aras et al [ 9 ] used silicone oil as endotamponade in all cases, while Foveau et al [ 10 ], Blanco-Teijeiro et al [ 11 ], Rao et al [ 7 ] and Nam et al [ 3 ] performed vitrectomy with gas in each case.…”

Section: Resultsmentioning

confidence: 98%

Internal limiting membrane peeling versus no peeling during primary vitrectomy for rhegmatogenous retinal detachment: A systematic review and meta-analysis

et al. 2018

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BackgroundInternal limiting membrane (ILM) peeling during primary vitrectomy for rhegmatogenous retinal detachment (RRD) prevents the formation of postoperative macular epiretinal membrane (ERM). However, studies that compared vitrectomy with and without ILM peeling for RRD, have reported controversial outcomes.ObjectiveTo assess the efficacy of ILM peeling versus non-ILM peeling during vitrectomy for RRD by a systematic review and meta-analysis of published studies.MethodsPubMed, Medline, Web of Science, Embase databases, and the Cochrane Library were searched up to April 2018 to identify studies that compared primary vitrectomy with and without ILM peeling for RRD with at least six months follow-up. Primary outcomes were the rate of postoperative ERM formation and mean best corrected visual acuity (BCVA) change after vitrectomy. Rate of recurrence of retinal detachment (RD) was assessed as secondary outcome. Risk ratios (RRs) with 95% confidence intervals (CIs) expressed pooled results for rate of ERM formation and rate of RD recurrence in ILM peeling and non-ILM peeling groups. Pooled results for BCVA change in the two groups were expressed as Weighted Mean Difference (WMD) with 95% CIs.ResultsNine studies, one of which was a randomized controlled trial (RCT), with a total number of 404 eyes in the ILM peeling group and 365 eyes in the non-ILM peeling group, were included. The analysis from pooled data indicated a significant lower rate of postoperative ERM formation in the ILM peeling group compared to the non-ILM peeling group (9 studies, 769 eyes, RR = 0.14; CI: 0.07 to 0.28; P < 0.001). There was no statistical difference in mean BCVA change (9 studies, 769 eyes, WMD = 0.02; CI: -0.11 to 0.16; P = 0.75). Rate of recurrence of RD was lower in the ILM peeling group (6 studies, 603 eyes, RR = 0.32; CI = 0.17 to 0.61; P< 0.001).ConclusionILM peeling during vitrectomy for RRD prevents the formation of macular epiretinal membrane postoperatively and reduces the incidence of RD recurrence, but better visual outcome was not found compared to non-ILM peeling vitrectomy.

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Section: Resultsmentioning

confidence: 98%

Internal limiting membrane peeling versus no peeling during primary vitrectomy for rhegmatogenous retinal detachment: A systematic review and meta-analysis

et al. 2018

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“…A successful surgery results in recovery of the finger function. Success in replantation is assessed by the ability to rebuild the vascular circulatory system [1][2][3]. The success rate is still low, in spite of the improvements in microsurgical techniques and the development of several new technologies [4].…”

Section: Introductionmentioning

confidence: 99%

Anti-thrombotic effect of combination of low molecular heparin and Xueshuantong after replantation of amputated finger

Huanwei¹,

Yang²,

Zhang³

et al. 2019

Trop. J. Pharm Res

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Purpose: To study the effects of low molecular heparin combined with Xueshuantong in preventing thrombosis after replantation of amputated finger. Methods: The treatment group (38 patients) was given 4500 IU of low molecular heparin sodium i.h. (hypodermic injection), q.d.(once daily), with 200 mL of 150 mg Xueshuantong injection and 5 % glucose injection, i.v.d. (intravenous drip), b.i.d. (twice daily). The control group received low molecular heparin sodium at 4500 IU i.h., q.d. alone. Treatment was for 3 days. Thereafter, D-dimer, fibrinogen, hemoglobin, platelets, prothrombin time (PT) and blood coagulation of patients in the 2 groups before and after treatment were compared. Differences in vasospasm, vascular thrombosis, finger necrosis, therapeutic effects and adverse reactions in patients in the 2 groups after treatment were recorded. Results: There were significant improvements in fibrinogen, platelet, PT levels, and blood coagulation time after treatment, with improvements better in the treatment group than in the control group (p < 0.05). Vasospasm cases (3) were lower in the treatment group than in the control group (8, p < 0.05), while vascular thrombosis and finger necrosis in both groups were comparable. Therapeutic effects and recovery were better in the treatment group than in the control group (p < 0.05). Conclusion: Combined injection of Xueshuantong and low molecular heparin exerts antithrombotic effects after replantation of amputated finger, improves coagulation function, and reduces incidence of vasospasm. It has better therapeutic effects than low molecular heparin, and it seems safe.

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“…On the contrary, MH and MH-retinal detachment (MHRD) necessitate the ILM peeling in order to release the tractional forces and may have greater benefit from surgical variants, such as the inverted ILM flap technique [ 35 , 42 ]. In the case of rhegmatogenous retinal detachment, ILM peeling seems to reduce the incidence of epiretinal membrane occurrence [ 43 ]; however, more studies are warranted to provide the indication to peel in this specific setting.…”

Section: Introductionmentioning

confidence: 99%

Vitrectomy in high myopia: a narrative review

et al. 2017

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Pathologic myopia is associated with degenerative changes of the globe, especially at the posterior pole. Eyes affected by pathologic myopia have higher odds to undergo posterior segment surgery and, in those eyes, vitreoretinal surgery is challenging. Many practical tips and tricks can make the surgical procedures simpler, significantly preventing sight-threatening intra- and post-operative complications. Moreover, novel surgical techniques and technological advancements (i.e. ad-hoc instrumentation, minimally invasive vitreoretinal surgery, filters, dye staining, intraoperative optical coherence tomography and 3-dimensional surgery) may play role in highly myopic eyes. The aim of the present work is to review practical tips and tricks, novel surgical techniques and technological advancements.Electronic supplementary materialThe online version of this article (doi:10.1186/s40942-017-0090-y) contains supplementary material, which is available to authorized users.

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Comparative Analysis of Retinal Reattachment Surgery With or Without Internal Limiting Membrane Peeling to Prevent Postoperative Macular Pucker

Abstract: Internal limiting membrane peeling during pars plana vitrectomy for rhegmatogenous retinal detachment significantly reduces ERM formation in the postoperative period and is associated with better visual and anatomical outcomes.

Cited by 38 publications

References 18 publications

Internal limiting membrane peeling versus no peeling during primary vitrectomy for rhegmatogenous retinal detachment: A systematic review and meta-analysis

Internal limiting membrane peeling versus no peeling during primary vitrectomy for rhegmatogenous retinal detachment: A systematic review and meta-analysis

Anti-thrombotic effect of combination of low molecular heparin and Xueshuantong after replantation of amputated finger

Vitrectomy in high myopia: a narrative review

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