Crossover clinical trial of pain relief in cataract surgery

Choi, Suvin; Park, Sang-Gue; Bellan, Lorne; Lee, Hyung-Hwan; Chung, Sung Kun

doi:10.1007/s10792-017-0554-y

Cited by 20 publications

(29 citation statements)

References 23 publications

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“…Prior studies have observed significant differences in pain relief between music and non-music conditions [ 11 , 37 , 38 ]. Differences have also been observed between music and other auditory conditions (i.e., white noise) [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

“…Music has been investigated as a potentially viable non-pharmacological treatment for alleviating pain [ 7 – 9 ]. Additionally, listening to music along with taking oral sedatives during cataract surgery reduced anxiety and enhanced comfort [ 10 ], diminishing the experience of pain during the surgery [ 11 ]. Recent research has revealed that music plays a critical role in dispersing harmful stimulants in order to transform cognitive faculties and emotions as an “audio analgesic” [ 9 , 12 – 14 ].…”

Section: Introductionmentioning

confidence: 99%

“…Crossover designs are useful for avoiding the influence of confounding factors while enhancing efficiency, controlling for individual differences by assigning each participant to all treatment conditions [ 23 , 24 ]. A previous study by Choi et al [ 11 ] utilized a 2x2 crossover design to show that music has an analgesic effect during cataract surgery. Following a similar design, we employed a 3x3 crossover design to compare music-listening, news-listening, and no-sound control conditions in relation to cold pressor pain (CPT) responses.…”

Section: Introductionmentioning

confidence: 99%

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The analgesic effect of music on cold pressor pain responses: The influence of anxiety and attitude toward pain

2018

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ObjectiveThe analgesic effect of music has been recognized for pain relief, but individual differences and adjuvant methods are poorly understood. This study employed a cold-pressor task (CPT) to observe the effects of music (without considering personal preferences) on pain experience and how this is affected by individuals’ general (and pain-specific) anxiety symptomology.MethodsFifty participants were each presented with three conditions (randomized into different orders): music-listening, news-listening, and no sound (control). Pain responses, including pain tolerance time (PT), pain intensity (PI), and pain unpleasantness (PU), were assessed using CPT and compared with a 3x3 crossover design. Participants also completed the anxiety sensitivity index (ASI-16) and pain anxiety symptom scale (PASS-20).ResultsCPT pain responses during the music intervention were significantly different from responses during the news intervention and control conditions, respectively. Among participants with normal anxiety levels, pain responses during the music condition differed significantly from the news and control groups; this was not the case for the anxiety risk group. Pain responses during the music condition for those with normal levels of pain-specific anxiety differed significantly from the control, but this was not the case for the risk group.ConclusionsMusic appears to influence diminished pain responses relative to the absence of an intervention. However, this was not the case when individuals listened to news stories. These effects were more robust for individuals experiencing normal levels of general and pain-specific anxiety. Thus, music (even outside one’s own preferences) was an effective adjuvant method for managing pain, especially among those without significant anxiety symptomology.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The analgesic effect of music on cold pressor pain responses: The influence of anxiety and attitude toward pain

2018

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“…A study of 121 randomly selected elderly patients [ 4 ] found that relaxing music during surgery led to a more satisfying experience. While several studies have shown similar results for cataract surgery [ 5 – 7 ], the benefits of music for intravitreal injection have not been well studied. Currently, there is only one randomized clinical trial conducted by Chen which suggested music could play a significant role in reducing anxiety during intravitreal injections, as reflected from the decrease in the anxiety level as measured by the state anxiety portion of the Spielberger State-Trait Anxiety Inventory (STAI-S) [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

“…Various types of music have been used in previous studies of their effect on patient experience in cataract surgery, including “classical music accompanied by soothing sounds of nature”, meditation music, and Korean traditional instrumental music [ 4 , 6 , 7 ]. The Korean study highlighted a possible cultural factor on the type of music in different populations [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Effect of Music on Patient Experience during Intravitreal Injection

Chan

Yeung

et al. 2020

Journal of Ophthalmology

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Introduction. Many patients remain anxious during intravitreal injections, despite its increasing use. As music can alleviate anxiety for other procedures, we wanted to evaluate its effect during intravitreal injection. Methods. Patients undergoing routine intravitreal injection were recruited for a randomized controlled trial. Subjects complete a State-Trait Anxiety Inventory (STAI-S) questionnaire before and after undergoing injection with or without background music. They were also assessed for subjective satisfaction, anxiety, pain, and future preferences after the injection. Results. There were 39 and 37 Chinese subjects in the music (age 68.08 ± 13.67) and control (age 73.24 ± 11.17) groups, respectively. The music group reported lower anxiety and pain, and a greater reduction in STAI-S score, but the differences were not statistically significant (P=0.830, 0.655, 0.199, respectively). More subjects in the music group (92.3%, control group 64.9%) preferred music for future injections (P=0.003). Age, but not the number of previous injections, was negatively correlated with reported anxiety (r = −0.27, P=0.021). Conclusion. Most subjects preferred music during future injections. Although music reduced anxiety, the effect was not statistically significant and may be masked by the higher age of our control group, as increasing age was correlated with lower anxiety.

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Efficacy of a Web App–Based Music Intervention During Cataract Surgery

Guerrier

Abdoul²,

Jilet³

et al. 2021

JAMA Ophthalmol

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IMPORTANCEHypertensive events during cataract surgery may induce complications. Information and communication technologies applied to health are popular, but clinical evidence of its usefulness is rare and limited to treating anxiety without specific analysis.Recent publications have described the potential effects of personalized music choices as mobile-based intervention on pain but not on anxiety.OBJECTIVE To demonstrate the effects of a web app-based music intervention on the incidence of hypertension in participants during cataract surgery performed under local anesthesia. DESIGN, SETTING, AND PARTICIPANTSThis randomized, single masked, controlled clinical trial was composed of 2 arms and took place at a single center at Cochin Hospital in Paris, France. A total of 313 participants were screened between February 2017 and July 2018. Among these, 311 participants undergoing a phacoemulsification procedure for elective surgery for their first eye cataract under local anesthesia were enrolled. Analysis was intention to treat and began in September 2018 and ended November 2018.INTERVENTIONS Participants requiring cataract surgery were assigned randomly to either the experimental arm (web app-based music listening intervention delivered via headphones) or control arm (noise-canceling headphones without music) for 20 minutes before surgery. MAIN OUTCOMES AND MEASURESThe occurrence of at least 1 hypertensive event during surgery.RESULTS A total of 310 participants were randomized in the study (155 to each arm) and 309 were analyzed (1 participant in the music arm had already undergone cataract surgery to the other eye). The mean (SD) age of the participants was 68.9 (10.8) years, and there were 176 female individuals (57%). On the primary end point, the incidence of hypertension was significantly lower in the music arm (21 [13.6%]) than in the control arm (82 [52.9%]), with a difference between the 2 arms of 39.3% (95% CI, 21.4%-48.9%; P < .001). Regarding the secondary end points, the mean (SD) visual measure of anxiety was lower in the music arm (1.4 [2.0]) than in the control arm (3.1 [2.4]), with a difference of 1.5 (95% CI, 1.0-2.1; P = .005). The mean (SD) number of sedative drug injections required during surgery was 0.04 (0.24) vs 0.54 (0.74) in the music vs control arms, respectively, with a difference of 0.50 (95% CI, 0.43-0.57; P < .001). CONCLUSIONS AND RELEVANCEFor participants similar to those enrolled in this study, the trial suggests that a web app-based personalized music intervention before cataract surgery may be considered to lower anxiety levels and hypertension or reduce the need for sedative medication.

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Crossover clinical trial of pain relief in cataract surgery

Cited by 20 publications

References 23 publications

The analgesic effect of music on cold pressor pain responses: The influence of anxiety and attitude toward pain

The analgesic effect of music on cold pressor pain responses: The influence of anxiety and attitude toward pain

Effect of Music on Patient Experience during Intravitreal Injection

Efficacy of a Web App–Based Music Intervention During Cataract Surgery

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