Anti-inflammatory activities of compounds from twigs of Morus alba

Tran, Huynh Nguyen Khanh; Nguyen, Van Thu; Kim, Jeong Ah.; Rho, Seong Soo; Woo, Mi Hee; Choi, Jae Sui; Lee, Jeong‐Hyung; Min, Byung Sun

doi:10.1016/j.fitote.2017.05.004

Cited by 31 publications

(13 citation statements)

References 29 publications

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“…Moreover this plant has been subject to numerous scientific investigations reporting analgesic [ 9 ], anti-inflammatory [ 8 , 9 ], and antioxidant [ 10 ] properties. Apigenin, a flavonoid isolated from the roots of Entada africana [ 11 ], was reported to display antioxidant activity [ 12 ], to inhibit cell proliferation [ 13 , 14 ], and to have anti-inflammatory activity [ 15 ]. The presence of this compound in Entada africana roots may account for its scientific proven properties [ 8 – 10 ].…”

Section: Introductionmentioning

confidence: 99%

The Root Aqueous Extract of Entada africana Guill. et Perr. (Mimosaceae) Inhibits Implant Growth, Alleviates Dysmenorrhea, and Restores Ovarian Dynamic in a Rat Model of Endometriosis

Mvondo

Essono

Tatsinkou

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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Entada africana (Mimosaceae) was reported to have analgesic and antioxidant properties. The present study is aimed at investigating the effects of the root aqueous extract of Entada africana (EA) on an experimental model of endometriosis. The study was performed in rats orally treated with EA at doses of 127.5, 255, and 510 mg/kg. Microgynon® 30 served as the reference substance. Estradiol valerate and oxytocin were used to induce dysmenorrhea. Endometrial implant levels of catalase and malondialdehyde (MDA) allowed estimating tissue oxidative status. Ovarian dynamic and rat sexual behavior were assessed through histological analysis of ovaries, uterus, and vagina. EA decreased dysmenorrhea at tested doses following a 7-day treatment (p < 0.001). Endometrial implant volume decreased following the three treatment periods (p < 0.05). Catalase activity (p < 0.001) and MDA level (p < 0.01) increased only following a 3-day treatment. EA also increased antral follicles, reduced luteinized unruptured follicle number (p < 0.001), and induced animals to be in the estrus phase. In conclusion, EA prevented the progress of endometriosis, reduced dysmenorrhea, promoted ovarian follicle growth, prevented anovulation, and stimulated the special period of rat sexual desire. These results suggest that Entada africana could be a promising alternative option for the treatment of endometriosis.

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Section: Introductionmentioning

confidence: 99%

The Root Aqueous Extract of Entada africana Guill. et Perr. (Mimosaceae) Inhibits Implant Growth, Alleviates Dysmenorrhea, and Restores Ovarian Dynamic in a Rat Model of Endometriosis

Mvondo

Essono

Tatsinkou

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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“…It has a vital function in the immune response to combat foreign invaders of the body (1,2). Under inflammatory condition, mast cells secrete chemokines and pro-inflammatory cytokines that cause angiectasis, increase permeability, and subsequently recruit leukocytes, macrophages and a wide range of immune cells to invade the affected area.…”

Section: Introductionmentioning

confidence: 99%

Punicalagin isolated from Punica granatum husk can decrease the inflammatory response in RAW 264.7 macrophages

Berköz¹,

Allahverdiyev²

2017

Eastern J Med

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“…During their perennial growth habit, trees have integrated multiple unique traits. In mulberry, unique traits such as rapid growth and biomass production, 31,32 leaf quality traits,- 13,33,34 plant insect/microbe interacting traits, [35][36][37][38][39][40][41] abiotic stress tolerance traits 42,43 and the traits associated with nutritional and medicinal values [44][45][46][47][48][49][50] have been studied. Mulberrysilkworm food chain also exhibits phytoremediation potential.…”

Section: Concept Of Model Systems and The Rise Of Perennial Systemsmentioning

confidence: 99%

Mulberry (Morus spp.) has the features to treat as a potential perennial model system

Dhanyalakshmi

Nataraja

2018

Plant Signaling & Behavior

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Mulberry (Morus spp.), a commercially exploited tree species as the host of monophagous pest silk worm (Bombyx mori), belongs to the family Moraceae. The domesticated tree has diverse beneficial characters such as traits associated with rapid growth and biomass production, plant insect/microbe interaction, abiotic stress tolerance and the traits associated with nutritional and medicinal values; some of which have been exploited. Draft genome of Morus notabilis has been sequenced and a large volume of transcriptome and genomic resources have been generated. In this review an attempt has been made to examine the options for considering mulberry as another tree model system to study unique traits associated with perennial systems. The diverse traits and features in mulberry suggest that the system can be a "comprehensive trait integrated tree system" quite different from other model tree systems.

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Anti-inflammatory activities of compounds from twigs of Morus alba

Cited by 31 publications

References 29 publications

The Root Aqueous Extract of Entada africana Guill. et Perr. (Mimosaceae) Inhibits Implant Growth, Alleviates Dysmenorrhea, and Restores Ovarian Dynamic in a Rat Model of Endometriosis

The Root Aqueous Extract of Entada africana Guill. et Perr. (Mimosaceae) Inhibits Implant Growth, Alleviates Dysmenorrhea, and Restores Ovarian Dynamic in a Rat Model of Endometriosis

Punicalagin isolated from Punica granatum husk can decrease the inflammatory response in RAW 264.7 macrophages

Mulberry (Morus spp.) has the features to treat as a potential perennial model system

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