285: Hypercalcemia Associated With Gluteal Silicone Injections: A Case Report

Singapuri, Salman; Patel, Daniel; Rahbari-Oskoui, Frederic

doi:10.1053/j.ajkd.2010.02.292

Cited by 4 publications

(2 citation statements)

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“…Also reported was the use of silicone with the help of transdermal ultrasound to remove wrinkles from the face and neck in one of the cases [5]. Hydration and steroids, with or without bisphosphonates, were the mainstay of treatment, but with improvement in only five cases [3, 5, 6, 12, 13]. Surgical excision of silicone granulomas helped normalize serum calcium in two of the reported cases, [9] and removal of breast implants resulted in improvement in one case [10].…”

Section: Discussionmentioning

confidence: 99%

Silicone-Induced Granulomatous Reaction Causing Severe Hypercalcemia: Case Report and Literature Review

Dangol

Negrete

2019

Case Reports in Nephrology

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A 67-year-old woman presented to the hospital with complaints of abdominal pain. Physical exam was significant for signs of severe dehydration, mild epigastric tenderness and multiple non-tender hard nodules over her arms and thighs. Incidental finding of severe hypercalcemia led to negative workups for hyperparathyroidism, vitamin D intoxication, and malignancy. However, elevated levels of 1,25-hydroxy vitamin D raised the possibility of granulomatous diseases. Imaging and patient report revealed silicone-induced foreign body granulomatous reaction as the cause of hypercalcemia. Use of silicone for cosmetic enhancement of body contours can result in siliconomas, severe hypercalcemia, and complications. Treatment is unestablished for this condition. Increasing prevalence of cosmetic enhancement should prompt vigilance for this rare disease entity. Providers should counsel and educate individuals undergoing such procedures.

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Section: Discussionmentioning

confidence: 99%

Silicone-Induced Granulomatous Reaction Causing Severe Hypercalcemia: Case Report and Literature Review

Dangol

Negrete

2019

Case Reports in Nephrology

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“…В настоящее время на рынке представлено более 50 марок, выпускающих свыше 160 инъекционных косметических составов для контурной пластики [10]. [17,18]. Тем не менее уровень кальцитриола может не повышаться, в отличие от увеличения активности фермента, особенно при дефиците 25-гидроксихолекальциферола [19].…”

Section: эпидемия косметических процедурunclassified

From the Desire to Change Appearance to Parathyroid Hormone-Independent Hypercalcemia: Complications of Cosmetic Injections

Egshatyan¹,

Voznyak²,

Yevloyeva³

et al. 2020

EPh

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Plastic surgery and cosmetic procedures, the number of which has been increasing exponentially in recent years, as well as related complications, have added to the list of parathyroid hormone-independent hypercalcemia causes. So, one of the delayed complications of silicone, paraffin oil, and polymethymethacrylate injections is hypercalcemia. Severe and sometimes life-threatening hypercalcemia can develop several years after cosmetic procedures. It is the result of granulomatous inflammation and most often extrarenal calcitriol synthesis by activated macrophages. Therefore, cosmetic post-injection granuloma should be considered as a cause of hypercalcemia, especially in middle-aged women who do not have parathyroid-mediated hypercalcemia or hypercalcemia in the outcome of paraneoplastic processes.

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Severe Granulomatous Reaction Associated With Hypercalcemia Occurring After Silicone Soft Tissue Augmentation of the Buttocks: A Case Report

et al. 2013

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285: Hypercalcemia Associated With Gluteal Silicone Injections: A Case Report

Cited by 4 publications

References 0 publications

Silicone-Induced Granulomatous Reaction Causing Severe Hypercalcemia: Case Report and Literature Review

Silicone-Induced Granulomatous Reaction Causing Severe Hypercalcemia: Case Report and Literature Review

From the Desire to Change Appearance to Parathyroid Hormone-Independent Hypercalcemia: Complications of Cosmetic Injections

Severe Granulomatous Reaction Associated With Hypercalcemia Occurring After Silicone Soft Tissue Augmentation of the Buttocks: A Case Report

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