Evaluation of <scp>OSMOCELLS</scp>, a new semi‐automatic device for osmotic fragility assessment

Gerard, Dava F.; Aj, Fattet; Brakta, C; Phulpin, Aurélie; Steschenko, Dominique; Jf, Lesesve; Perrin, Julien

doi:10.1111/ijlh.12683

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2022

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Cited by 2 publications

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References 22 publications

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“…Osmotic fragility was assessed using Osmocell device (SD Medical) as previously described 25 . Briefly, blood samples were diluted (1/40) in 0.9% NaCl isotonic saline solution and analyzed using osmocell system.…”

Section: Methodsmentioning

confidence: 99%

Multiparametric characterization of red blood cell physiology after hypotonic dialysis based drug encapsulation process

Robert

Laperrousaz

Piedrahita

et al. 2022

Acta Pharmaceutica Sinica B

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Section: Methodsmentioning

confidence: 99%

Multiparametric characterization of red blood cell physiology after hypotonic dialysis based drug encapsulation process

Robert

Laperrousaz

Piedrahita

et al. 2022

Acta Pharmaceutica Sinica B

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“…OFT di dalam laboratorium hematologi ditegakkan untuk membantu diagnosis beberapa jenis anemia. Prinsip pemeriksaan OFT adalah menilai kekuatan membrane sel eritrosit menggunakan larutan salin yang diencerkan bertingkat (Gérard et al, 2017). Batas normal OFT adalah pada konsentrasi 0,32%-0,44%.…”

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Konfirmasi Hasil Osmotic Fragility Test (Oft) Berdasarkan Kadar Hemoglobin

Maggyasari

Santosa²

2022

MAK

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Erythrocyte fragility is the reaction of the erythrocyte membrane to oppose the osmotic pressure of the surrounding solution. Several influencing factors are haemoglobin levels, erythrocyte shape, erythrocyte lifespan, and lipoprotein content of the erythrocyte membrane. The purpose of the study was to determine the results of the osmotic fragility test (OFT) based on haemoglobin levels. The research method was descriptive with a population of Unimus MLT students. A sample of 20 people and specimens in the form of venous blood was checked for Hb levels using a haematology analyser and OFT levels using a series of test tube dilutions. The results showed that the average OFT levels were 0.37±1.67 and Hb levels were 13.39±0.01. Complete lysis occurred with OFT level 0.46% at Hb level ≥15 g/dl. In conclusion, OFT levels and average Hb levels are still within normal limits, there are 4 Hb levels below normal or mild anemia with normal OFT levels, while Hb levels ≥15 g/dl have OFT levels above normal.

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Evaluation of OSMOCELLS, a new semi‐automatic device for osmotic fragility assessment

Abstract: The device offers a substantial improvement in terms of standardization and consistency of the results and may offer a considerable gain for general laboratories.

Cited by 2 publications

References 22 publications

Multiparametric characterization of red blood cell physiology after hypotonic dialysis based drug encapsulation process

Multiparametric characterization of red blood cell physiology after hypotonic dialysis based drug encapsulation process

Konfirmasi Hasil Osmotic Fragility Test (Oft) Berdasarkan Kadar Hemoglobin

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