Nutritional Deficiency and Acquired Ichthyosis

Holzman, Samuel; Durso, Samuel C.

doi:10.1007/s11606-017-4070-6

Cited by 4 publications

(3 citation statements)

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“…Similarly, AI has been seldomly reported with vitamin-deficient states and in malabsorptive disease. 7,8 The mechanism for nutritional dermatoses is unknown, but essential fatty acid deficiency and free radical production have been suggested (Table 1). 4,9…”

Section: N U Tr Itiona L Defici E Nci E Smentioning

confidence: 99%

“…Despite the prevalence of ISC in this study, only lichenoid skin changes were shown to be a significant predictor of death. Similarly, AI has been seldomly reported with vitamin‐deficient states and in malabsorptive disease 7,8 . The mechanism for nutritional dermatoses is unknown, but essential fatty acid deficiency and free radical production have been suggested (Table 1).…”

Section: Nutritional Deficienciesmentioning

confidence: 99%

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Acquired ichthyosis, asteatotic dermatitis or xerosis? An update on pathoetiology and drug‐induced associations

Park

Saeidian

Youssefian

et al. 2022

Acad Dermatol Venereol

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Acquired ichthyosis (AI) or conditions mimicking ichthyosis have been documented for well over a century. AI is limited to the skin, but can be the first presenting sign of an underlying disease or an adverse effect of select medications or environmental exposures. 1,2 Most heritable ichthyoses, with the exceptions of late-onset ichthyosis vulgaris (IV) and Refsum disease, typically manifest between the immediate postnatal period and 5 years of age. 2 AI, however, does not follow an obvious age distribution; rather, the appearance and disappearance of AI tend to coincide with onset and resolution of an inciting factor. Clinically, AI closely resembles IV with diffuse, symmetrically distributed, white-to-brown scales which can be confused with severe cases of xerosis or eczema (Figure 1a-c). 1 Histopathology of AI usually shows varying degrees of orthohyperkeratosis, a uniformly diminished or absent granular layer, and lack of dermal inflammation. 1,3 In patients with suspected AI, a detailed investigation into the clinical course typically does not yield personal or family history of ichthyosis, atopy, keratosis pilaris or other keratodermaassociated phenotypes seen with the heritable ichthyoses. 1,2 In this article, we provide an up-to-date overview of AI and the pathomechanisms suggested in the literature. While the associated clinical features in many cases of AI are unknown, detailed examples are provided for the medical conditions, medications and exposures with clinical importance. In

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Section: N U Tr Itiona L Defici E Nci E Smentioning

confidence: 99%

Section: Nutritional Deficienciesmentioning

confidence: 99%

Acquired ichthyosis, asteatotic dermatitis or xerosis? An update on pathoetiology and drug‐induced associations

Park

Saeidian

Youssefian

et al. 2022

Acad Dermatol Venereol

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“…В работах отечественных и зарубежных авторов приводятся многочисленные причины приобретенного ихтиоза: чрезмерный уход за кожей (встречается в основном у лиц зрелого возраста); злокачественные опухоли [29-32]; почечная недостаточность; аутоиммунные заболевания; инфекционные заболевания (как правило, ВИЧ инфекция и туберкулез); употребление определенных препаратов (гиполипидемические, психотропные, циметидин, клофазимин) [33]; недостаточно сбалансированное питание (недостаточность витамина А, кахексия) [34]; расстройства гормонального характера (гипотиреоз, гиперпаратиреоз, пангипопитуитаризм) [35,36]; хронические воспалительные заболевания кишечника (неспецифический язвенный колит, болезнь Крона). Патогенез приобретенного ихтиоза до настоящего времени недостаточно изучен.…”

Section: разделunclassified

Ichthyosis (concept, pathohistology, clinical picture, treatment)

Takhtarova

Геннадьевна²,

Хисматуллина

et al. 2021

Vestnik dermatologii i venerologii

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Ichthyosis is a skin disease that is hereditary, has pronounced symptoms in the form of a violation of the skin, and the presence of formations resembling fish scales. It is possible to distinguish different approaches to the definition of ichthyosis, based on the modern study of this issue. Ichthyosis is classified by type: congenital and acquired. Congenital ichthyosis has its own classification depending on the manifestation of changes in the skin, the course of the disease, concomitant pathologies. Congenital ichthyosis is divided into ordinary (vulgar autosomal dominant, simple) ichthyosis, lamellar ichthyosis (dry ichthyosiform erythroderma, "collodion child", lamellar ichthyosis), X-linked ichthyosis (ichthyosis associated with the X chromosome, blackening ichthyosis), congenital bullous ichthyosiform erythroderma (erythroderma Broca's disease, ichthyosiform epidermolytic hyperkeratosis), fetal ichthyosis (intrauterine ichthyosis, universal hyperkeratosis, "Harlequin fetus", congenital keratosis), other congenital ichthyosis. Ichthyosiform conditions (the so-called acquired ichthyosis) are divided into symptomatic, age-related (senile), discoid ichthyosis. The causes of acquired ichthyosis can be various diseases, taking medications, improper skin care, unbalanced nutrition. Each form of ichthyosis differs by the type of inheritance, prevalence in the population, clinical picture, verified by histological examination of skin biopsies and electron microscopic examination of the skin. It may be accompanied by seasonality of exacerbation of the clinical picture, association with other diseases (allergic, diseases of the gastrointestinal tract, congenital malformations). There is no specific treatment for ichthyosis. In systemic therapy, derivatives of vitamin A are used, keratolytics, as well as moisturizing and emollient agents are used for external treatment. The use of therapeutic baths, general ultraviolet irradiation is effective.

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